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Protein
Submitted name:

Secretin receptor

Gene

SCTR

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionG-protein coupled receptorSAAS annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
Secretin receptorImported
Gene namesi
Name:SCTRImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiHostDB:ENSG00000080293.9.
HGNCiHGNC:10608. SCTR.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei169 – 189HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000080293.

Expressioni

Gene expression databases

BgeeiENSG00000080293.
ExpressionAtlasiA0A0D9SFY2. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliA0A0D9SFY2.
SMRiA0A0D9SFY2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini69 – 152G_PROTEIN_RECEP_F2_3InterPro annotationAdd BLAST84
Domaini167 – 243G_PROTEIN_RECEP_F2_4InterPro annotationAdd BLAST77

Sequence similaritiesi

Belongs to the G-protein coupled receptor 2 family.SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00760000118800.

Family and domain databases

Gene3Di4.10.1240.10. 1 hit.
InterProiView protein in InterPro
IPR017981. GPCR_2-like.
IPR036445. GPCR_2_extracell_dom_sf.
IPR001879. GPCR_2_extracellular_dom.
IPR000832. GPCR_2_secretin-like.
IPR017983. GPCR_2_secretin-like_CS.
IPR002144. GPCR_2_secretin_rcpt.
PANTHERiPTHR12011:SF29. PTHR12011:SF29. 1 hit.
PfamiView protein in Pfam
PF00002. 7tm_2. 1 hit.
PF02793. HRM. 1 hit.
PRINTSiPR00249. GPCRSECRETIN.
PR00490. SECRETINR.
SMARTiView protein in SMART
SM00008. HormR. 1 hit.
SUPFAMiSSF111418. SSF111418. 1 hit.
PROSITEiView protein in PROSITE
PS00649. G_PROTEIN_RECEP_F2_1. 1 hit.
PS50227. G_PROTEIN_RECEP_F2_3. 1 hit.
PS50261. G_PROTEIN_RECEP_F2_4. 1 hit.

Sequencei

Sequence statusi: Fragment.

A0A0D9SFY2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPVIPALWEA EVRGSLEPKS SRPAWATWVF SPCSIMLEFP ETMGFSKNQT
60 70 80 90 100
GALPRLCDVL QVLWEEQDQC LQELSREQTG DLGTEQPVPG CEGMWDNISC
110 120 130 140 150
WPSSVPGRMV EVECPRFLRM LTSRNGSLFR NCTQDGWSET FPRPNLACGV
160 170 180 190 200
NVNDSSNEKR HSYLLKLKVM YTVGYSSSLV MLLVALGILC AFRRLHCTRN
210 220 230 240
YIHMHLFVSF ILRALSNFIK DAVLFSSDDV TYCDAHRAGC KLV
Length:243
Mass (Da):27,481
Last modified:May 27, 2015 - v1
Checksum:i5596A8431B57BDC9
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei243Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC013275 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000627145; ENSP00000486987; ENSG00000080293.

Similar proteinsi

Entry informationi

Entry nameiA0A0D9SFY2_HUMAN
AccessioniPrimary (citable) accession number: A0A0D9SFY2
Entry historyiIntegrated into UniProtKB/TrEMBL: May 27, 2015
Last sequence update: May 27, 2015
Last modified: November 22, 2017
This is version 18 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported