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Protein
Submitted name:

Forkhead box protein M1

Gene

FOXM1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi235 – 328Fork-headPROSITE-ProRule annotationAdd BLAST94

GO - Molecular functioni

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Forkhead box protein M1Imported
Gene namesi
Name:FOXM1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 12

Organism-specific databases

EuPathDBiHostDB:ENSG00000111206.12.
HGNCiHGNC:3818. FOXM1.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotation

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000111206.

PTM / Processingi

Proteomic databases

EPDiA0A0D9SFF0.
PeptideAtlasiA0A0D9SFF0.

Expressioni

Gene expression databases

BgeeiENSG00000111206.
ExpressionAtlasiA0A0D9SFF0. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliA0A0D9SFF0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini235 – 328Fork-headInterPro annotationAdd BLAST94

Phylogenomic databases

GeneTreeiENSGT00790000123003.

Family and domain databases

CDDicd00059. FH. 1 hit.
Gene3Di1.10.10.10. 1 hit.
InterProiView protein in InterPro
IPR001766. Fork_head_dom.
IPR018122. TF_fork_head_CS_1.
IPR030456. TF_fork_head_CS_2.
IPR036388. WH-like_DNA-bd_sf.
IPR036390. WH_DNA-bd_sf.
PfamiView protein in Pfam
PF00250. Forkhead. 1 hit.
PRINTSiPR00053. FORKHEAD.
SMARTiView protein in SMART
SM00339. FH. 1 hit.
SUPFAMiSSF46785. SSF46785. 1 hit.
PROSITEiView protein in PROSITE
PS00657. FORK_HEAD_1. 1 hit.
PS00658. FORK_HEAD_2. 1 hit.
PS50039. FORK_HEAD_3. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A0D9SFF0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKTSPRRPLI LKRRRLPLPV QNAPSETSEE EPKRSPAQQE SNQAEASKEV
60 70 80 90 100
AESNSCKFPA GIKIINHPTM PNTQVVAIPN NANIHSIITA LTAKGKESGS
110 120 130 140 150
SGPNKFILIS CGGAPTQPPG LRPQTQTSYD AKRTEVTLET LGPKPAARDV
160 170 180 190 200
NLPRPPGALC EQKRETCDGE AAGCTINNSL SNIQWLRKMS SDGLGSRSIK
210 220 230 240 250
QEMEEKENCH LEQRQVKVEE PSRPSASWQN SVSERPPYSY MAMIQFAINS
260 270 280 290 300
TERKRMTLKD IYTWIEDHFP YFKHIAKPGW KNSIRHNLSL HDMFVRETSA
310 320 330 340 350
NGKVSFWTIH PSANRYLTLD QVFKQQQKRP NPELRRNMTI KTELPLGARR
360 370 380 390 400
KMKPLLPRVS SYLVPIQFPV NQSLVLQPSV KVPLPLAASL MSSELARHSK
410 420 430 440 450
RVRIAPKVLL AEEGIAPLSS AGPGKEEKLL FGEGFSPLLP VQTIKEEEIQ
460 470 480 490 500
PGEEMPHLAR PIKVESPPLE EWPSPAPSFK EESSHSWEDS SQSPTPRPKK
510 520 530 540 550
SYSGLRSPTR CVSEMLVIQH RERRERSRSR RKQHLLPPCV DEPELLFSEG
560 570 580 590 600
PSTSRWAAEL PFPADSSDPA SQLSYSQEVG GPFKTPIKET LPISSTPSKS
610 620 630 640 650
VLPRTPESWR LTPPAKVGGL DFSPVQTSQG ASDPLPDPLG LMDLSTTPLQ
660 670 680 690 700
SAPPLESPQR LLSSEPLDLI SVPFGNSSPS DIDVPKPGSP EPQVSGLAAN
710 720 730 740
RSLTEGLVLD TMNDSLSKIL LDISFPGLDE DPLGPDNINW SQFIPELQ
Length:748
Mass (Da):82,742
Last modified:May 27, 2015 - v1
Checksum:i78E1F5F0EAA66F95
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC005841 Genomic DNA. No translation available.
AC005911 Genomic DNA. No translation available.
RefSeqiNP_001230017.1. NM_001243088.1.
UniGeneiHs.239.
Hs.735243.

Genome annotation databases

EnsembliENST00000627656; ENSP00000486536; ENSG00000111206.
GeneIDi2305.

Similar proteinsi

Entry informationi

Entry nameiA0A0D9SFF0_HUMAN
AccessioniPrimary (citable) accession number: A0A0D9SFF0
Entry historyiIntegrated into UniProtKB/TrEMBL: May 27, 2015
Last sequence update: May 27, 2015
Last modified: January 31, 2018
This is version 28 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported