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Protein

Phosphodiesterase

Gene

PDE4D

Organism
Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Protein inferred from homologyi

Functioni

Cofactori

a divalent metal cationUniRule annotationNote: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseUniRule annotationSAAS annotation
LigandMetal-bindingUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
PhosphodiesteraseUniRule annotation (EC:3.1.4.-UniRule annotation)
Gene namesi
Name:PDE4DImported
OrganismiChlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus)Imported
Taxonomic identifieri60711 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeChlorocebus
Proteomesi
  • UP000029965 Componenti: Chromosome 4

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini293 – 534PDEase_IInterPro annotationAdd BLAST242

Sequence similaritiesi

Belongs to the cyclic nucleotide phosphodiesterase family.UniRule annotationSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00760000118889.
OMAiQHEVEMP.

Family and domain databases

CDDicd00077. HDc. 1 hit.
Gene3Di1.10.1300.10. 1 hit.
InterProiView protein in InterPro
IPR003607. HD/PDEase_dom.
IPR023088. PDEase.
IPR002073. PDEase_catalytic_dom.
IPR036971. PDEase_catalytic_dom_sf.
IPR023174. PDEase_CS.
PfamiView protein in Pfam
PF00233. PDEase_I. 1 hit.
PRINTSiPR00387. PDIESTERASE1.
PROSITEiView protein in PROSITE
PS00126. PDEASE_I. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A0D9RUC1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTSPGSGLIL QANFVHSQRR ESFLYRSDSD YDLSPKSMSR NSSIASDIHG
60 70 80 90 100
DDLIVTPFAQ VLASLRTVRN NFAALTNLQD RAPSKRSPMC NQPSINKATI
110 120 130 140 150
TEEAYQKLAS ETLEELDWCL DQLETLQTRH SVSEMASNKF KRMLNRELTH
160 170 180 190 200
LSEMSRSGNQ VSEFISNTFL DKQHEVEIPS PTQKEKEKKK RPMSQISGVK
210 220 230 240 250
KLMHSSSLTN SSIPRFGVKT EQEDVLAKEL EDVNKWGLHV FRIAELSGNR
260 270 280 290 300
PLTVIMHTIF QERDLLKTFK IPVDTLITYL MTLEDHYHAD VAYHNNIHAA
310 320 330 340 350
DVVQSTHVLL STPALEAVFT DLEILAAIFA SAIHDVDHPG VSNQFLINTN
360 370 380 390 400
SELALMYNDS SVLENHHLAV GFKLLQEENC DIFQNLTKKQ RQSLRKMVID
410 420 430 440 450
IVLATDMSKH MNLLADLKTM VETKKVTSSG VLLLDNYSDR IQVLQNMVHC
460 470 480 490 500
ADLSNPTKPL QLYRQWTDRI MEEFFRQGDR ERERGMEISP MCDKHNASVE
510 520 530 540 550
KSQVGFIDYI VHPLWETWAD LVHPDAQDIL DTLEDNREWY QSTIPQSPSP
560 570 580 590 600
APDDPEEGRQ GQTEKFQFEL TLEEDGESDT EKDSGSQVEE DTSCSDSKTL
610 620 630 640
CTQDSESTEI PLDEQVEEEA VGEEEESQSE ACVIDDRSPD T
Length:641
Mass (Da):72,769
Last modified:May 27, 2015 - v1
Checksum:i06D9CEAECDBF8D3E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AQIB01086488 Genomic DNA. No translation available.
AQIB01086489 Genomic DNA. No translation available.
AQIB01086490 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSCSAT00000014232; ENSCSAP00000012210; ENSCSAG00000016138.

Similar proteinsi

Entry informationi

Entry nameiA0A0D9RUC1_CHLSB
AccessioniPrimary (citable) accession number: A0A0D9RUC1
Entry historyiIntegrated into UniProtKB/TrEMBL: May 27, 2015
Last sequence update: May 27, 2015
Last modified: October 25, 2017
This is version 14 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported