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Protein

Protein kinase C

Gene

PRKCI

Organism
Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.SAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Serine/threonine-protein kinaseUniRule annotationSAAS annotation, Transferase
LigandATP-bindingUniRule annotationSAAS annotation, Metal-binding, Nucleotide-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Protein kinase CSAAS annotation (EC:2.7.11.13SAAS annotation)
Gene namesi
Name:PRKCIImported
OrganismiChlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus)Imported
Taxonomic identifieri60711 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeChlorocebus
Proteomesi
  • UP000029965 Componenti: Chromosome 15

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini26 – 76Phorbol-ester/DAG-typeInterPro annotationAdd BLAST51
Domaini140 – 408Protein kinaseInterPro annotationAdd BLAST269
Domaini409 – 480AGC-kinase C-terminalInterPro annotationAdd BLAST72

Sequence similaritiesi

Belongs to the protein kinase superfamily.UniRule annotation

Keywords - Domaini

Zinc-fingerSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00820000126964.
OMAiKGDIMIT.

Family and domain databases

CDDicd00029. C1. 1 hit.
cd05618. STKc_aPKC_iota. 1 hit.
InterProiView protein in InterPro
IPR000961. AGC-kinase_C.
IPR034661. aPKC_iota.
IPR020454. DAG/PE-bd.
IPR011009. Kinase-like_dom_sf.
IPR002219. PE/DAG-bd.
IPR017892. Pkinase_C.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
PfamiView protein in Pfam
PF00130. C1_1. 1 hit.
PF00069. Pkinase. 1 hit.
PF00433. Pkinase_C. 1 hit.
PRINTSiPR00008. DAGPEDOMAIN.
SMARTiView protein in SMART
SM00109. C1. 1 hit.
SM00133. S_TK_X. 1 hit.
SM00220. S_TKc. 1 hit.
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiView protein in PROSITE
PS51285. AGC_KINASE_CTER. 1 hit.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
PS00479. ZF_DAG_PE_1. 1 hit.
PS50081. ZF_DAG_PE_2. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A0D9RJT0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPCPGEDKSI YRRGARRWRK LYCANGHTFQ AKRFNRRAHC AICTDRIWGL
60 70 80 90 100
GRQGYKCINC KLLVHKKCHK LVTIECGRHS LPPEPVMPMD QSSMHSDHAQ
110 120 130 140 150
TVIPYNPSSH ESLDQVGEEK EAMNTRESGK ASSSLGLQDF DLLRVIGRGS
160 170 180 190 200
YAKVLLVRLK KTDRIYAMKV VKKELVNDDE DIDWVQTEKH VFEQASNHPF
210 220 230 240 250
LVGLHSCFQT ESRLFFVIEY VNGGDLMFHM QRQRKLPEEH ARFYSAEISL
260 270 280 290 300
ALNYLHERGI IYRDLKLDNV LLDSEGHIKL TDYGMCKEGL RPGDTTSTFC
310 320 330 340 350
GTPNYIAPEI LRGEDYGFSV DWWALGVLMF EMMAGRSPFD IVGSSDNPDQ
360 370 380 390 400
NTEDYLFQVI LEKQIRIPRS LSVKAASVLK SFLNKDPKER LGCHPQTGFA
410 420 430 440 450
DIQGHPFFRN VDWDMMEQKQ VVPPFKPNIS GEFGLDNFDS QFTNEPVQLT
460 470 480
PDDDDIVRKI DQSEFEGFEY INPLLMSAEE CV
Length:482
Mass (Da):55,290
Last modified:May 27, 2015 - v1
Checksum:i859DDCF368B84C9A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AQIB01118964 Genomic DNA. No translation available.
AQIB01118965 Genomic DNA. No translation available.
AQIB01118966 Genomic DNA. No translation available.
AQIB01118967 Genomic DNA. No translation available.
AQIB01118968 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSCSAT00000010781; ENSCSAP00000008869; ENSCSAG00000012687.

Similar proteinsi

Entry informationi

Entry nameiA0A0D9RJT0_CHLSB
AccessioniPrimary (citable) accession number: A0A0D9RJT0
Entry historyiIntegrated into UniProtKB/TrEMBL: May 27, 2015
Last sequence update: May 27, 2015
Last modified: November 22, 2017
This is version 16 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported