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Protein

Phosphoglycerate kinase

Gene

pgk

Organism
Neisseria sp. HMSC06F02
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotationSAAS annotation

Pathwayi: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes pyruvate from D-glyceraldehyde 3-phosphate.UniRule annotationSAAS annotation
Proteins known to be involved in the 5 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Phosphoglycerate kinase (pgk)
  3. 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase (gpmA)
  4. Enolase (eno)
  5. Pyruvate kinase (HMPREF3156_02597)
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes pyruvate from D-glyceraldehyde 3-phosphate, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei105SubstrateUniRule annotation1
Binding sitei183SubstrateUniRule annotation1
Binding sitei216SubstrateUniRule annotation1
Binding sitei267ATPUniRule annotation1
Binding sitei389ATPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi415 – 418ATPUniRule annotation4

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseUniRule annotationSAAS annotationImported, Transferase
Biological processGlycolysisUniRule annotationSAAS annotation
LigandATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

UniPathwayiUPA00109; UER00185.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinaseUniRule annotationSAAS annotation (EC:2.7.2.3UniRule annotationSAAS annotation)
Gene namesi
Name:pgkUniRule annotation
ORF Names:HMPREF3156_01564Imported
OrganismiNeisseria sp. HMSC06F02Imported
Taxonomic identifieri1581124 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNeisserialesNeisseriaceaeNeisseria
Proteomesi
  • UP000032443 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Monomer.UniRule annotationSAAS annotation

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni90 – 92Substrate bindingUniRule annotation3
Regioni128 – 131Substrate bindingUniRule annotation4

Sequence similaritiesi

Belongs to the phosphoglycerate kinase family.UniRule annotationSAAS annotation

Family and domain databases

Gene3Di3.40.50.1260. 3 hits.
HAMAPiMF_00145. Phosphoglyc_kinase. 1 hit.
InterProiView protein in InterPro
IPR001576. Phosphoglycerate_kinase.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
IPR036043. Phosphoglycerate_kinase_sf.
PANTHERiPTHR11406. PTHR11406. 1 hit.
PfamiView protein in Pfam
PF00162. PGK. 1 hit.
PIRSFiPIRSF000724. Pgk. 1 hit.
PRINTSiPR00477. PHGLYCKINASE.
SUPFAMiSSF53748. SSF53748. 1 hit.
PROSITEiView protein in PROSITE
PS00111. PGLYCERATE_KINASE. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A0D9LP27-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGNYTVNRAG ETGERSSEKR DLRFQTTFYI DAAADANQAQ ANPAFTDAPR
60 70 80 90 100
SRIIENIPIS VSNLHKGYIM AFLKLTEQNV QGKTVLIRAD MNVPFKDGKI
110 120 130 140 150
SDDTRIRASL ASIKYCLDNG ASVIVMTHLG RPTEGEFHPE DDVAPVAAHL
160 170 180 190 200
GGLLGKDVKV LNDWRENKPA LKAGDVVMLQ NVRINKGEKK NDLELGKAYA
210 220 230 240 250
ALCDVFVNDA FGTAHRAQAS TEAVAQAAPV ACAGVLMAGE LDALGKALKQ
260 270 280 290 300
PARPMVAIVA GSKVSTKLTI LESLADKVDQ LIVGGGIANT FLLAEGKAIG
310 320 330 340 350
KSLAEHDLVE ESKKIMAKMA AKGGSVPLPT DVVVAKAFAA DAEAVVKDIA
360 370 380 390 400
DVAEDDMILD IGPKSAAALA ELLKAAGTVV WNGPVGVFEF DQFAGGTKAL
410 420 430 440 450
AEAIAQSKAF SIAGGGDTLA AIAKFGVTDQ IGYISTGGGA FLEFLEGKEL
460
PAVAALEKRG A
Length:461
Mass (Da):48,242
Last modified:May 27, 2015 - v1
Checksum:i7278C420A6A7E57C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JZWO01000157 Genomic DNA. Translation: KJJ16233.1.

Genome annotation databases

EnsemblBacteriaiKJJ16233; KJJ16233; HMPREF3156_01564.
PATRICifig|1581124.3.peg.1504.

Similar proteinsi

Entry informationi

Entry nameiA0A0D9LP27_9NEIS
AccessioniPrimary (citable) accession number: A0A0D9LP27
Entry historyiIntegrated into UniProtKB/TrEMBL: May 27, 2015
Last sequence update: May 27, 2015
Last modified: March 28, 2018
This is version 19 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteomeImported