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Protein
Submitted name:

Glutamate--cysteine ligase catalytic subunit

Gene

GCLC

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Glutamate--cysteine ligase catalytic subunitImported
Gene namesi
Name:GCLCImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 6

Organism-specific databases

EuPathDBiHostDB:ENSG00000001084.10
HGNCiHGNC:4311 GCLC

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000001084

PTM / Processingi

Proteomic databases

PeptideAtlasiA0A0C4DGB2

Expressioni

Gene expression databases

BgeeiENSG00000001084
ExpressionAtlasiA0A0C4DGB2 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliA0A0C4DGB2
SMRiA0A0C4DGB2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiKOG3754 Eukaryota
ENOG410XQIG LUCA
GeneTreeiENSGT00390000011908

Family and domain databases

InterProiView protein in InterPro
IPR004308 GCS
IPR014746 Gln_synth/guanido_kin_cat_dom
PANTHERiPTHR11164 PTHR11164, 1 hit
SUPFAMiSSF55931 SSF55931, 2 hits

Sequencei

Sequence statusi: Complete.

A0A0C4DGB2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGLLSQGSPL SWEETKRHAD HVRRHGILQF LHIYHAVKDR HKDVLKWGDE
60 70 80 90 100
VEYMLVSFDH ENKKVRLVLS GEKVLETLQE KGERTNPNHP TLWRPEYGSY
110 120 130 140 150
MIEGTPGQPY GGTMSEFNTV EANMRKRRKE ATSILEENQA LCTITSFPRL
160 170 180 190 200
GCPGFTLPEV KPNPVEGGAS KSLFFPDEAI NKHPRFSTLT RNIRHRRGEK
210 220 230 240 250
VVINVPIFKD KNTPSPFIET FTEDDEASRA SKPDHIYMDA MGFGMGNCCL

QV
Length:252
Mass (Da):28,752
Last modified:April 1, 2015 - v1
Checksum:iFFE1AF8A2C3BB1B3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL033397 Genomic DNA No translation available.
UniGeneiHs.654465

Genome annotation databases

EnsembliENST00000514004; ENSP00000421908; ENSG00000001084

Similar proteinsi

Entry informationi

Entry nameiA0A0C4DGB2_HUMAN
AccessioniPrimary (citable) accession number: A0A0C4DGB2
Entry historyiIntegrated into UniProtKB/TrEMBL: April 1, 2015
Last sequence update: April 1, 2015
Last modified: June 20, 2018
This is version 31 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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