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Protein
Submitted name:

PX domain-containing protein kinase-like protein

Gene

PXK

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
PX domain-containing protein kinase-like proteinImported
Gene namesi
Name:PXKImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 3

Organism-specific databases

EuPathDBiHostDB:ENSG00000168297.15
HGNCiHGNC:23326 PXK

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000168297

PTM / Processingi

Proteomic databases

EPDiA0A0C4DG95
MaxQBiA0A0C4DG95
PeptideAtlasiA0A0C4DG95

Expressioni

Gene expression databases

BgeeiENSG00000168297
ExpressionAtlasiA0A0C4DG95 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliA0A0C4DG95
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 109PXInterPro annotationAdd BLAST109
Domaini71 – 464Protein kinaseInterPro annotationAdd BLAST394

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili399 – 419Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG410IF7B Eukaryota
ENOG410Z20X LUCA
GeneTreeiENSGT00390000017669

Family and domain databases

Gene3Di3.30.1520.10, 1 hit
InterProiView protein in InterPro
IPR011009 Kinase-like_dom_sf
IPR001683 Phox
IPR000719 Prot_kinase_dom
IPR036871 PX_dom_sf
PfamiView protein in Pfam
PF00069 Pkinase, 1 hit
PF00787 PX, 1 hit
SMARTiView protein in SMART
SM00312 PX, 1 hit
SUPFAMiSSF56112 SSF56112, 1 hit
SSF64268 SSF64268, 1 hit
PROSITEiView protein in PROSITE
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS50195 PX, 1 hit

Sequencei

Sequence statusi: Complete.

A0A0C4DG95-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAFMEKPPAG KVLLDDTVPL TAAIEASQSL QSHTIVRRYS DFDLLNNSLQ
60 70 80 90 100
IAGLSLPLPP KKLIGNMDRE FIAERQKGLQ NYLNVITTNH ILSNCELVKK
110 120 130 140 150
FLDPNNYSAN YTEIALQQVS MFFRSEPKWE VVEPLKDIGW RIRKKYFLMK
160 170 180 190 200
IKNQPKERLV LSWADLGPDK YLSDKDFQCL IKLLPSCLHP YIYRVTFATA
210 220 230 240 250
NESSALLIRM FNEKGTLKDL IYKAKPKDPF LKKYCNPKKI QGLELQQIKT
260 270 280 290 300
YGRQILEVLK FLHDKGFPYG HLHASNVMLD GDTCRLLDLE NSLLGLPSFY
310 320 330 340 350
RSYFSQFRKI NTLESVDVHC FGHLLYEMTY GRPPDSVPVD SFPPAPSMAV
360 370 380 390 400
VAVLESTLSC EACKNGMPTI SRLLQMPLFS DVLLTTSEKP QFKIPTKLKE
410 420 430 440 450
ALRIAKECIE KRLIEEQKQI HQHRRLTRAQ SHHGSEEERK KRKILARKKS
460 470 480 490 500
KRSALENSEE HSAKYSNSNN SGSGASSPLT SPSSPTPPST SAALGLSKRC
510 520 530 540 550
KERDICITST SSTSTTTSSS LASCEHRGTC PALVSGCEWH EPRGLAQLHP
560
EFPKRNFEES QNL
Length:563
Mass (Da):63,752
Last modified:April 1, 2015 - v1
Checksum:i8391BE955CDC4540
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC098479 Genomic DNA No translation available.
AC135507 Genomic DNA No translation available.
RefSeqiNP_001276024.1, NM_001289095.1
UniGeneiHs.190544

Genome annotation databases

EnsembliENST00000479241; ENSP00000419049; ENSG00000168297
GeneIDi54899

Similar proteinsi

Entry informationi

Entry nameiA0A0C4DG95_HUMAN
AccessioniPrimary (citable) accession number: A0A0C4DG95
Entry historyiIntegrated into UniProtKB/TrEMBL: April 1, 2015
Last sequence update: April 1, 2015
Last modified: May 23, 2018
This is version 27 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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