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Protein

Transcription termination/antitermination protein NusG

Gene

nusG

Organism
Yersinia intermedia
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the RNA polymerase (RNAP), probably by partially suppressing pausing. In the presence of Rho, modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho. May be required to overcome a kinetic limitation of Rho to function at certain terminators. Also involved in ribosomal RNA transcriptional antitermination.UniRule annotation

GO - Biological processi

Keywordsi

Biological processTranscription, Transcription antiterminationUniRule annotationSAAS annotation, Transcription regulation, Transcription terminationUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Transcription termination/antitermination protein NusGUniRule annotationSAAS annotation
Gene namesi
Name:nusGUniRule annotationImported
Synonyms:nusG_2Imported
ORF Names:CBW57_20965Imported, ERS008449_04143Imported, ERS008476_04205Imported, ERS008530_04739Imported, ERS008547_04129Imported
OrganismiYersinia intermediaImported
Taxonomic identifieri631 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesYersiniaceaeYersinia
Proteomesi
  • UP000043316 Componenti: Unassembled WGS sequence
  • UP000042195 Componenti: Unassembled WGS sequence
  • UP000196440 Componenti: Unassembled WGS sequence
  • UP000045423 Componenti: Unassembled WGS sequence
  • UP000038750 Componenti: Unassembled WGS sequence

Interactioni

Subunit structurei

Monomer. Interacts with the transcription termination factor Rho and with RNA polymerase.UniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini6 – 115NGNInterPro annotationAdd BLAST110
Domaini127 – 154KOWInterPro annotationAdd BLAST28

Sequence similaritiesi

Belongs to the NusG family.UniRule annotationSAAS annotation

Phylogenomic databases

KOiK02601.

Family and domain databases

Gene3Di2.30.30.30. 1 hit.
3.30.70.940. 1 hit.
HAMAPiMF_00948. NusG. 1 hit.
InterProiView protein in InterPro
IPR005824. KOW.
IPR006645. NGN_dom.
IPR036735. NGN_dom_sf.
IPR014722. Rib_L2_dom2.
IPR001062. Transcrpt_antiterm_NusG.
IPR015869. Transcrpt_antiterm_NusG_bac_CS.
IPR008991. Translation_prot_SH3-like_sf.
PANTHERiPTHR30265:SF2. PTHR30265:SF2. 1 hit.
PfamiView protein in Pfam
PF00467. KOW. 1 hit.
PF02357. NusG. 1 hit.
PRINTSiPR00338. NUSGTNSCPFCT.
SMARTiView protein in SMART
SM00739. KOW. 1 hit.
SM00738. NGN. 1 hit.
SUPFAMiSSF50104. SSF50104. 1 hit.
SSF82679. SSF82679. 1 hit.
TIGRFAMsiTIGR00922. nusG. 1 hit.
PROSITEiView protein in PROSITE
PS01014. NUSG. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A0B6I9A9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEAPKKRWY VVQAFSGFEG RVAQSLREHI KLHDMEELFG EVMVPTEEVV
60 70 80 90 100
EIRGGQRRKS ERKFFPGYVL VQMVMNDASW HLVRSVPRVM GFIGGTSDRP
110 120 130 140 150
APISDKEVDA IMNRLQQVGD KPRPKTLFEP GELVRVSDGP FADFNGVVEE
160 170 180
VDYEKSRLKV SVSIFGRATP VELDFSQVEK G
Length:181
Mass (Da):20,514
Last modified:April 1, 2015 - v1
Checksum:iC078FF359DFE1826
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CPZJ01000040 Genomic DNA. Translation: CNG79487.1.
CQER01000022 Genomic DNA. Translation: CNL99368.1.
CTFA01000081 Genomic DNA. Translation: CQD59200.1.
CWJI01000024 Genomic DNA. Translation: CRY57154.1.
NHOI01000038 Genomic DNA. Translation: OVZ82132.1.
RefSeqiWP_002210671.1. NZ_NHOI01000038.1.

Genome annotation databases

EnsemblBacteriaiCNG79487; CNG79487; ERS008530_04739.
CNL99368; CNL99368; ERS008547_04129.
CQD59200; CQD59200; ERS008449_04143.
CRY57154; CRY57154; ERS008476_04205.
GeneIDi31914128.
KEGGiyin:CH53_2090.

Similar proteinsi

Entry informationi

Entry nameiA0A0B6I9A9_YERIN
AccessioniPrimary (citable) accession number: A0A0B6I9A9
Entry historyiIntegrated into UniProtKB/TrEMBL: April 1, 2015
Last sequence update: April 1, 2015
Last modified: December 20, 2017
This is version 30 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported