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Protein
Submitted name:

Degringolade, isoform D

Gene

dgrn

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

  • RNA polymerase II repressing transcription factor binding Source: FlyBase
  • SUMO binding Source: FlyBase
  • ubiquitin protein ligase activity Source: FlyBase
  • zinc ion binding Source: FlyBase

GO - Biological processi

  • double-strand break repair via homologous recombination Source: FlyBase
  • neurogenesis Source: FlyBase
  • positive regulation of transcription, DNA-templated Source: FlyBase
  • protein ubiquitination Source: FlyBase
  • regulation of embryonic development Source: FlyBase
  • regulation of establishment of protein localization Source: FlyBase
  • regulation of protein binding Source: FlyBase
  • sex determination Source: FlyBase

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Degringolade, isoform DImported
Gene namesi
Name:dgrnImported
Synonyms:DgrnImported, Dmel\CG10981Imported, STUbLImported
ORF Names:CG10981Imported, Dmel_CG10981Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 3R

Organism-specific databases

FlyBaseiFBgn0037384 dgrn

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

ExpressionAtlasiA0A0B4LHT4 baseline and differential

Interactioni

GO - Molecular functioni

  • RNA polymerase II repressing transcription factor binding Source: FlyBase
  • SUMO binding Source: FlyBase

Structurei

3D structure databases

SMRiA0A0B4LHT4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini152 – 192RING-typeInterPro annotationAdd BLAST41

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili15 – 35Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis, Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0320 Eukaryota
ENOG410XV78 LUCA
GeneTreeiENSGT00730000112978
OrthoDBiEOG091G0AKN

Family and domain databases

Gene3Di3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR001841 Znf_RING
IPR013083 Znf_RING/FYVE/PHD
IPR017907 Znf_RING_CS
PfamiView protein in Pfam
PF13639 zf-RING_2, 1 hit
SMARTiView protein in SMART
SM00184 RING, 1 hit
PROSITEiView protein in PROSITE
PS00518 ZF_RING_1, 1 hit
PS50089 ZF_RING_2, 1 hit

Sequencei

Sequence statusi: Complete.

A0A0B4LHT4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MANLSVSTED AHSQIRSLTQ DVIQMEAELD RMNRYCEEVV AQIDTFATRT
60 70 80 90 100
STPTTRRIRR RTSPVEVIDL SHLDRAPPVR SARNRDPDAF IDLCTPEGPR
110 120 130 140 150
SRTVNLHSND SLTILPRRSA ENDPVVDLDV ASPPKRVNRD IDESQKEELY
160 170 180 190 200
KCPICMDSVS KREPVSTKCG HVFCRECIET AIRATHKCPI CNKKLTARQF

FRIYL
Length:205
Mass (Da):23,412
Last modified:April 1, 2015 - v1
Checksum:i863A852000127DD8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014297 Genomic DNA Translation: AHN57187.1
RefSeqiNP_001287188.1, NM_001300259.1
UniGeneiDm.1077

Genome annotation databases

EnsemblMetazoaiFBtr0344116; FBpp0310533; FBgn0037384
GeneIDi40725
KEGGidme:Dmel_CG10981

Similar proteinsi

Entry informationi

Entry nameiA0A0B4LHT4_DROME
AccessioniPrimary (citable) accession number: A0A0B4LHT4
Entry historyiIntegrated into UniProtKB/TrEMBL: April 1, 2015
Last sequence update: April 1, 2015
Last modified: June 20, 2018
This is version 32 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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