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Protein

3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ

Gene

fabZ

Organism
Lysinibacillus manganicus DSM 26584
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.UniRule annotationSAAS annotation

Catalytic activityi

A (3R)-3-hydroxyacyl-[acyl-carrier protein] = a trans-2-enoyl-[acyl-carrier protein] + H2O.UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei48UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyaseUniRule annotationSAAS annotation
Biological processLipid A biosynthesisUniRule annotationSAAS annotation, Lipid biosynthesis, Lipid metabolism

Names & Taxonomyi

Protein namesi
Recommended name:
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZUniRule annotation (EC:4.2.1.59UniRule annotation)
Alternative name(s):
(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydrataseUniRule annotation
Short name:
(3R)-hydroxymyristoyl-ACP dehydraseUniRule annotation
Beta-hydroxyacyl-ACP dehydrataseUniRule annotation
Gene namesi
Name:fabZUniRule annotation
ORF Names:CD29_01955Imported
OrganismiLysinibacillus manganicus DSM 26584Imported
Taxonomic identifieri1384049 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeLysinibacillus
Proteomesi
  • UP000030416 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini11 – 133FabAInterPro annotationAdd BLAST123

Sequence similaritiesi

Belongs to the thioester dehydratase family. FabZ subfamily.UniRule annotationSAAS annotation

Family and domain databases

HAMAPiMF_00406. FabZ. 1 hit.
InterProiView protein in InterPro
IPR013114. FabA_FabZ.
IPR010084. FabZ.
IPR029069. HotDog_dom_sf.
PfamiView protein in Pfam
PF07977. FabA. 1 hit.
SUPFAMiSSF54637. SSF54637. 1 hit.
TIGRFAMsiTIGR01750. fabZ. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A0A3I5Y7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLHADQIQEI LPHRYPFLLV DRIIEVEEGK RAVGLKNVSI NEDFFNGHFP
60 70 80 90 100
GYPVMPGVLI IEALAQVGGV ALLKSEQFKG RLAFLTGIDN ARFKRQVVPG
110 120 130 140
DQLRLEVEFV RMRGQMGKGH AIATVDGELV CEADILFAIG PAQPK
Length:145
Mass (Da):16,048
Last modified:February 4, 2015 - v1
Checksum:i75ABB1E62D376493
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JPVN01000002 Genomic DNA. Translation: KGR80144.1.
RefSeqiWP_036182267.1. NZ_JPVN01000002.1.

Genome annotation databases

EnsemblBacteriaiKGR80144; KGR80144; CD29_01955.

Similar proteinsi

Entry informationi

Entry nameiA0A0A3I5Y7_9BACI
AccessioniPrimary (citable) accession number: A0A0A3I5Y7
Entry historyiIntegrated into UniProtKB/TrEMBL: February 4, 2015
Last sequence update: February 4, 2015
Last modified: November 22, 2017
This is version 16 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported