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Protein
Submitted name:

Paired box protein Pax-2

Gene

PAX2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDevelopmental proteinSAAS annotation, DNA-bindingPROSITE-ProRule annotationSAAS annotation
Biological processTranscription, Transcription regulationPROSITE-ProRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Paired box protein Pax-2Imported
Gene namesi
Name:PAX2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 10

Organism-specific databases

EuPathDBiHostDB:ENSG00000075891.21.
HGNCiHGNC:8616. PAX2.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000075891.

Expressioni

Gene expression databases

BgeeiENSG00000075891.
ExpressionAtlasiA0A0A0MRH7. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliA0A0A0MRH7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini15 – 141PairedInterPro annotationAdd BLAST127

Keywords - Domaini

Paired boxPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00680000099553.

Family and domain databases

CDDicd00131. PAX. 1 hit.
Gene3Di1.10.10.10. 2 hits.
InterProiView protein in InterPro
IPR009057. Homeobox-like_sf.
IPR001523. Paired_dom.
IPR022130. Pax2_C.
IPR036388. WH-like_DNA-bd_sf.
PfamiView protein in Pfam
PF00292. PAX. 1 hit.
PF12403. Pax2_C. 1 hit.
PRINTSiPR00027. PAIREDBOX.
SMARTiView protein in SMART
SM00351. PAX. 1 hit.
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiView protein in PROSITE
PS00034. PAIRED_1. 1 hit.
PS51057. PAIRED_2. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A0A0MRH7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDMHCKADPF SAMHRHGGVN QLGGVFVNGR PLPDVVRQRI VELAHQGVRP
60 70 80 90 100
CDISRQLRVS HGCVSKILGR YYETGSIKPG VIGGSKPKVA TPKVVDKIAE
110 120 130 140 150
YKRQNPTMFA WEIRDRLLAE GICDNDTVPS VSSINRIIRT KVQQPFHPTP
160 170 180 190 200
DGAGTGVTAP GHTIVPSTAS PPVSSASNDP VGSYSINGIL GIPRSNGEKR
210 220 230 240 250
KRDEDVSEGS VPNGDSQSGV DSLRKHLRAD TFTQQQLEAL DRVFERPSYP
260 270 280 290 300
DVFQASEHIK SEQGNEYSLP ALTPGLDEVK SSLSASTNPE LGSNVSGTQT
310 320 330 340 350
YPVVTGRDMA STTLPGYPPH VPPTGQGSYP TSTLAGMVPG SEFSGNPYSH
360 370 380 390
PQYTAYNEAW RFSNPALLSS PYYYSAAPRG SAPAAAAAAY DRH
Length:393
Mass (Da):42,179
Last modified:January 7, 2015 - v1
Checksum:i4D57753399454C05
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL138762 Genomic DNA. No translation available.
AL589862 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000361791; ENSP00000355069; ENSG00000075891.
UCSCiuc010qps.3. human.

Similar proteinsi

Entry informationi

Entry nameiA0A0A0MRH7_HUMAN
AccessioniPrimary (citable) accession number: A0A0A0MRH7
Entry historyiIntegrated into UniProtKB/TrEMBL: January 7, 2015
Last sequence update: January 7, 2015
Last modified: November 22, 2017
This is version 22 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported