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Protein
Submitted name:

DNA-binding protein Ikaros

Gene

IKZF1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
DNA-binding protein IkarosImported
Gene namesi
Name:IKZF1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 7

Organism-specific databases

EuPathDBiHostDB:ENSG00000185811.16
HGNCiHGNC:13176 IKZF1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000185811

PTM / Processingi

Proteomic databases

EPDiA0A0A0MRA0
PeptideAtlasiA0A0A0MRA0

Expressioni

Gene expression databases

BgeeiENSG00000185811
ExpressionAtlasiA0A0A0MRA0 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliA0A0A0MRA0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini194 – 214C2H2-typeInterPro annotationAdd BLAST21

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00550000074392

Family and domain databases

InterProiView protein in InterPro
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
SMARTiView protein in SMART
SM00355 ZnF_C2H2, 2 hits
SUPFAMiSSF57667 SSF57667, 1 hit
PROSITEiView protein in PROSITE
PS00028 ZINC_FINGER_C2H2_1, 1 hit

Sequencei

Sequence statusi: Complete.

A0A0A0MRA0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDADEGQDMS QVSGDKGLSD TPYDSSASYE KENEMMKSHV MDQAINNAIN
60 70 80 90 100
YLGAESLRPL VQTPPGGSEV VPVISPMYQL HKPLAEGTPR SNHSAQDSAV
110 120 130 140 150
ENLLLLSKAK LVPSEREASP SNSCQDSTDT ESNNEEQRSG LIYLTNHIAP
160 170 180 190 200
HARNGLSLKE EHRAYDLLRA ASENSQDALR VVSTSGEQMK VYKCEHCRVL
210 220 230 240
FLDHVMYTIH MGCHGFRDPF ECNMCGYHSQ DRYEFSSHIT RGEHRFHMS
Length:249
Mass (Da):27,850
Last modified:January 7, 2015 - v1
Checksum:i716989FF54D0D099
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC124014 Genomic DNA No translation available.
AC233268 Genomic DNA No translation available.
AUXG01000057 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000346667; ENSP00000340080; ENSG00000185811
UCSCiuc022acs.2 human

Similar proteinsi

Entry informationi

Entry nameiA0A0A0MRA0_HUMAN
AccessioniPrimary (citable) accession number: A0A0A0MRA0
Entry historyiIntegrated into UniProtKB/TrEMBL: January 7, 2015
Last sequence update: January 7, 2015
Last modified: June 20, 2018
This is version 34 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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