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Protein
Submitted name:

Potassium voltage-gated channel subfamily Q member 4

Gene

KCNQ4

Organism
Papio anubis (Olive baboon)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIon channel, Potassium channelSAAS annotation
Biological processIon transport, Potassium transport, Transport
LigandPotassium

Names & Taxonomyi

Protein namesi
Submitted name:
Potassium voltage-gated channel subfamily Q member 4Imported
Gene namesi
Name:KCNQ4Imported
OrganismiPapio anubis (Olive baboon)Imported
Taxonomic identifieri9555 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaePapio
Proteomesi
  • UP000028761 Componenti: Chromosome 1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei99 – 121HelicalSequence analysisAdd BLAST23
Transmembranei133 – 152HelicalSequence analysisAdd BLAST20
Transmembranei173 – 191HelicalSequence analysisAdd BLAST19
Transmembranei242 – 260HelicalSequence analysisAdd BLAST19
Transmembranei299 – 325HelicalSequence analysisAdd BLAST27

Keywords - Cellular componenti

Membrane

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini100 – 325Ion_transInterPro annotationAdd BLAST226
Domaini465 – 647KCNQ_channelInterPro annotationAdd BLAST183

Sequence similaritiesi

Belongs to the potassium channel family.SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00550000074513.
OMAiWAFVYHV.
OrthoDBiEOG091G02ZT.

Family and domain databases

InterProiView protein in InterPro
IPR005821. Ion_trans_dom.
IPR003937. K_chnl_volt-dep_KCNQ.
IPR013821. K_chnl_volt-dep_KCNQ_C.
IPR015573. KCQN4.
IPR028325. VG_K_chnl.
PANTHERiPTHR11537. PTHR11537. 1 hit.
PTHR11537:SF4. PTHR11537:SF4. 1 hit.
PfamiView protein in Pfam
PF00520. Ion_trans. 1 hit.
PF03520. KCNQ_channel. 1 hit.
PRINTSiPR00169. KCHANNEL.
PR01459. KCNQCHANNEL.

Sequencei

Sequence statusi: Complete.

A0A096NYR8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
QPQSPGKRAG LGPSPGDAPR AELVALTAVQ SEQGEAGGGG SPRRLGLLGS
60 70 80 90 100
PLPPGAPLPG LGSGSGSACG QRSSAAHKRY RRLQNWVYNV LERPRGWAFV
110 120 130 140 150
YHVFIFLLVF SCLVLSVLST IQEHQELANE CLLILEFVMI VVFGLEYIVR
160 170 180 190 200
VWSAGCCCRY RGWQGRFRFA RKPFCVIDFI VFVASVAVIA AGTQGNIFAT
210 220 230 240 250
SALRSMRFLQ ILRMVRMDRR GGTWKLLGSV VYAHSKRGRI TAWYIGFLVL
260 270 280 290 300
IFASFLVYLA EKDANSDFSS YADSLWWGTI TLTTIGYGDK TPHTWLGRVL
310 320 330 340 350
AAGFALLGIS FFALPAGILG SGFALKVQEQ HRQKHFEKRR MPAANLIQAA
360 370 380 390 400
WRLYSTDMSR AYLTATWYYY DSILPSFREL ALLFEHVQRA RNGGLRPLEV
410 420 430 440 450
RRAPVPDGAP SRYPPVATCH RPGSTSFCPG ESSRMGIKDR IRMGSSQRRT
460 470 480 490 500
GPSKQHLAPP TMPTSPSSEQ AGEAGSPTKV QKSWSFNDRT RFRASLRLKP
510 520 530 540 550
RTSAEEAPSE EVAEEKGYQC ELTVDDVMPA VKTVIRSVRI LKFLVAKRKF
560 570 580 590 600
KETLRPYDVK DVIEQYSAGH LDMLGRIKSL QTRVDQIVGR GPGDRKAREK
610 620 630 640 650
GDKGPSDAEV VDEISMMGRV VKVEKQVQSI EHKLDLLLGF YSRCLRSGTS
660 670 680 690
ASLGTVQVPL FDSDITSDYH SPVDHEDISV SAQTLSISRS VSTNVD
Length:696
Mass (Da):77,034
Last modified:November 26, 2014 - v1
Checksum:i9C0A4955F6E34C41
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AHZZ01050840 Genomic DNA. No translation available.
AHZZ01050841 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSPANT00000005047; ENSPANP00000018233; ENSPANG00000006225.

Similar proteinsi

Entry informationi

Entry nameiA0A096NYR8_PAPAN
AccessioniPrimary (citable) accession number: A0A096NYR8
Entry historyiIntegrated into UniProtKB/TrEMBL: November 26, 2014
Last sequence update: November 26, 2014
Last modified: October 25, 2017
This is version 19 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported