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Protein

Cytochrome P450

Gene

CYP1A2

Organism
Papio anubis (Olive baboon)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Cytochromes P450 are a group of heme-thiolate monooxygenases.UniRule annotation

Catalytic activityi

RH + [reduced NADPH--hemoprotein reductase] + O2 = ROH + [oxidized NADPH--hemoprotein reductase] + H2O.UniRule annotation

Cofactori

hemeUniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMonooxygenaseUniRule annotation, Oxidoreductase
LigandHemeUniRule annotation, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome P450UniRule annotation (EC:1.14.14.1UniRule annotation)
Gene namesi
Name:CYP1A2Imported
OrganismiPapio anubis (Olive baboon)Imported
Taxonomic identifieri9555 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaePapio
Proteomesi
  • UP000028761 Componenti: Chromosome 7

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Endoplasmic reticulum, MicrosomeUniRule annotation

Interactioni

GO - Molecular functioni

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome P450 family.UniRule annotation

Phylogenomic databases

GeneTreeiENSGT00900000140831.
OMAiLHEMTKV.
OrthoDBiEOG091G0BT8.

Family and domain databases

Gene3Di1.10.630.10. 1 hit.
InterProiView protein in InterPro
IPR001128. Cyt_P450.
IPR017972. Cyt_P450_CS.
IPR002401. Cyt_P450_E_grp-I.
IPR008066. Cyt_P450_E_grp-I_CYP1.
IPR036396. Cyt_P450_sf.
PfamiView protein in Pfam
PF00067. p450. 1 hit.
PRINTSiPR00463. EP450I.
PR01683. EP450ICYP1A.
PR00385. P450.
SUPFAMiSSF48264. SSF48264. 1 hit.
PROSITEiView protein in PROSITE
PS00086. CYTOCHROME_P450. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A096NMR5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALSQSVPFS ATELLLASAI FCLVFWVLRG SRPQVPKGLK SPPEPWGWPL
60 70 80 90 100
LGHVLTLGKN PHLALSRMSQ LYGDVLQIRI GSTPVLVLSG LDTIRQALVR
110 120 130 140 150
QGDDFKGRPD LYSFTFITDG QSMSFSPDSG PVWAARRRLA QNALNTFSIA
160 170 180 190 200
SDPASSSSCY LEEHVSKEAE ALSSRLQELM AGPGHFDPYN QVVVSVANVI
210 220 230 240 250
GAMCFGQHYP ESSDEMLSLV KNSHEFVESA SSGNPVDFFP ILRYLPNPAL
260 270 280 290 300
QRFKAFNQRF RQFLQKTVQE HYQDFDKNSV QDITGALFKH SKKGPRASGN
310 320 330 340 350
LIPQEKIVNL VNDIFGAGFD TIATAISWSL MYLVTKPEIQ RKIQKELDAV
360 370 380 390 400
IGRGRRPRLS DRLQLPYLEA FILETFRHSS FVPFTIPHST TRDTTLNGFY
410 420 430 440 450
IPRECCVFIN QWQVNHDPQL WGDPSEFRPE RFLTAEGTTI NKPLSEKIML
460 470 480 490 500
FGLGKRRCIG EVLGKWEVFL FLAILLQQLE FSVPPGVKVD LTPIYGLTMK
510
HARCEHFQAR LRFSIK
Length:516
Mass (Da):58,121
Last modified:February 28, 2018 - v2
Checksum:iF18CD3EA38C2084E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AHZZ02031286 Genomic DNA. No translation available.
RefSeqiXP_003901256.1. XM_003901207.3.

Genome annotation databases

EnsembliENSPANT00000004824; ENSPANP00000014274; ENSPANG00000015999.

Similar proteinsi

Entry informationi

Entry nameiA0A096NMR5_PAPAN
AccessioniPrimary (citable) accession number: A0A096NMR5
Entry historyiIntegrated into UniProtKB/TrEMBL: November 26, 2014
Last sequence update: February 28, 2018
Last modified: March 28, 2018
This is version 23 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported