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Protein
Submitted name:

Capping actin protein of muscle Z-line alpha subunit 1

Gene

CAPZA1

Organism
Papio anubis (Olive baboon)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

F-actin-capping proteins bind in a Ca2+-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.SAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionActin cappingSAAS annotation, Actin-bindingSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Capping actin protein of muscle Z-line alpha subunit 1Imported
Gene namesi
Name:CAPZA1Imported
OrganismiPapio anubis (Olive baboon)Imported
Taxonomic identifieri9555 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaePapio
Proteomesi
  • UP000028761 Componenti: Chromosome 1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

ExpressionAtlasiA0A096MX18. baseline.

Interactioni

Subunit structurei

Heterodimer of an alpha and a beta subunit.SAAS annotation

GO - Molecular functioni

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili219 – 246Sequence analysisAdd BLAST28

Sequence similaritiesi

Belongs to the F-actin-capping protein alpha subunit family.SAAS annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

GeneTreeiENSGT00390000006476.
OMAiACDSALR.
OrthoDBiEOG091G0KST.

Family and domain databases

InterProiView protein in InterPro
IPR002189. CapZ_alpha.
IPR037282. CapZ_alpha/beta.
IPR017865. F-actin_cap_asu_CS.
PANTHERiPTHR10653. PTHR10653. 1 hit.
PfamiView protein in Pfam
PF01267. F-actin_cap_A. 1 hit.
PRINTSiPR00191. FACTINCAPA.
SUPFAMiSSF90096. SSF90096. 1 hit.
PROSITEiView protein in PROSITE
PS00748. F_ACTIN_CAPPING_A_1. 1 hit.
PS00749. F_ACTIN_CAPPING_A_2. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A096MX18-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
KQDIFFKGCD ENFVRIAAKF ITHAPPGEFN EVFNDVRLLL NNDNLLREGA
60 70 80 90 100
AHAFAQYNMD QFTPVKIEGY EDQVLITEHG DLGNSRFLDP RNKISFKFDH
110 120 130 140 150
LRKEASDPQP EEVDGGLKSW RESCDSALRA YVKDHYSNGF CTGVYAKTID
160 170 180 190 200
GQQTIIACIE SHQFQPKNFW NGRWRSEWKF TITPPTAQVV GVLKIQVHYY
210 220 230 240 250
EDGNVQLVSH KDVQDSLTVS NEAQTAKEFI KIIENAENEY QTAISENYQT
260 270 280
MSDTTFKALR RQLPVTRTKI DWNKILSYKI GKEMQNA
Length:287
Mass (Da):33,042
Last modified:November 26, 2014 - v1
Checksum:i03F546F6DD820480
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AHZZ01021508 Genomic DNA. No translation available.
AHZZ01021509 Genomic DNA. No translation available.
AHZZ01021510 Genomic DNA. No translation available.
AHZZ01021511 Genomic DNA. No translation available.
AHZZ01021512 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSPANT00000022777; ENSPANP00000004428; ENSPANG00000016077.

Similar proteinsi

Entry informationi

Entry nameiA0A096MX18_PAPAN
AccessioniPrimary (citable) accession number: A0A096MX18
Entry historyiIntegrated into UniProtKB/TrEMBL: November 26, 2014
Last sequence update: November 26, 2014
Last modified: November 22, 2017
This is version 22 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported