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Protein

Transporter

Gene

SLC6A3

Organism
Papio anubis (Olive baboon)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processSymportUniRule annotationSAAS annotation, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
TransporterUniRule annotation
Gene namesi
Name:SLC6A3Imported
OrganismiPapio anubis (Olive baboon)Imported
Taxonomic identifieri9555 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaePapio
Proteomesi
  • UP000028761 Componenti: Chromosome 6

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei69 – 87HelicalSequence analysisAdd BLAST19
Transmembranei99 – 120HelicalSequence analysisAdd BLAST22
Transmembranei141 – 168HelicalSequence analysisAdd BLAST28
Transmembranei238 – 255HelicalSequence analysisAdd BLAST18
Transmembranei267 – 291HelicalSequence analysisAdd BLAST25
Transmembranei311 – 332HelicalSequence analysisAdd BLAST22
Transmembranei352 – 372HelicalSequence analysisAdd BLAST21
Transmembranei392 – 418HelicalSequence analysisAdd BLAST27
Transmembranei447 – 472HelicalSequence analysisAdd BLAST26
Transmembranei478 – 501HelicalSequence analysisAdd BLAST24
Transmembranei522 – 544HelicalSequence analysisAdd BLAST23
Transmembranei556 – 578HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Membrane

Interactioni

GO - Molecular functioni

Family & Domainsi

Sequence similaritiesi

Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00760000118857.
OMAiYAAYKFC.
OrthoDBiEOG091G08PX.

Family and domain databases

InterProiView protein in InterPro
IPR000175. Na/ntran_symport.
IPR002436. Na/ntran_symport_dopamine.
IPR037272. SNS_sf.
PANTHERiPTHR11616. PTHR11616. 1 hit.
PfamiView protein in Pfam
PF00209. SNF. 1 hit.
PRINTSiPR01202. DOPTRANSPORT.
PR00176. NANEUSMPORT.
SUPFAMiSSF161070. SSF161070. 1 hit.
PROSITEiView protein in PROSITE
PS00610. NA_NEUROTRAN_SYMP_1. 1 hit.
PS00754. NA_NEUROTRAN_SYMP_2. 1 hit.
PS50267. NA_NEUROTRAN_SYMP_3. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A096MN61-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKSKCSVGL MSSVVAPAKE PNAMGPKEVE LILVKEQNGV QLTSSTLTNP
60 70 80 90 100
RQSPVEAQDR ETWGKKIDFL LSVIGFAVDL ANVWRFPYLC YKNGGGAFLV
110 120 130 140 150
PYLLFMVIAG MPLFYMELAL GQFNREGAAG VWKICPVLKG VGFTVILISL
160 170 180 190 200
YVGFFYNVII AWALHYLFSS FTTELPWIHC NNSWNSPNCS DAHSGDSGGN
210 220 230 240 250
GSGLNDTFGT TPAAEYFERG VLHLHQSHGI DDLGPPRWQL TACLVLVIVL
260 270 280 290 300
LYFSLWKGVK TSGKVVWITA TMPYVVLTAL LLRGVTLPGA IDGIRAYLSV
310 320 330 340 350
DFYRLCEASV WIDAATQVCF SLGVGFGVLI AFSSYNKFTN NCYRDAIVTT
360 370 380 390 400
SINSLTSFSS GFVVFSFLGY MAQKHSVPIG DVAKDGPGLI FIIYPEAIAT
410 420 430 440 450
LPLSSAWAVV FFIMLLTLGI DSAMGGMESV ITGLIDEFQL LHRHRELFTL
460 470 480 490 500
FIVLATFLLS LFCVTNGGIY VFTLLDHFAA GTSILFGVLI EAIGVAWFYG
510 520 530 540 550
VGQFSDDIQQ MTGQRPSLYW RLCWKLVSPC FLLFVVVVSI VTFRPPHYGA
560 570 580 590 600
YIFPDWANAL GWVIATSSMA MVPIYAAYKF CSLPGSFREK LAYAIAPEKD
610 620
RELVDRGEVR QFTLRHWLKV
Length:620
Mass (Da):68,442
Last modified:November 26, 2014 - v1
Checksum:i34EFFD88C0BB83A5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AHZZ01191499 Genomic DNA. No translation available.
AHZZ01191500 Genomic DNA. No translation available.
AHZZ01191501 Genomic DNA. No translation available.
AHZZ01191502 Genomic DNA. No translation available.
AHZZ01191503 Genomic DNA. No translation available.
RefSeqiXP_003899511.1. XM_003899462.2.

Genome annotation databases

EnsembliENSPANT00000013370; ENSPANP00000001053; ENSPANG00000014160.
GeneIDi101022805.

Similar proteinsi

Entry informationi

Entry nameiA0A096MN61_PAPAN
AccessioniPrimary (citable) accession number: A0A096MN61
Entry historyiIntegrated into UniProtKB/TrEMBL: November 26, 2014
Last sequence update: November 26, 2014
Last modified: November 22, 2017
This is version 22 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported