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Protein
Submitted name:

Glutamate receptor ionotropic, NMDA 3A

Gene

Grin3a

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIon channel, Ligand-gated ion channelSAAS annotation, ReceptorSAAS annotation
Biological processIon transport, Transport

Names & Taxonomyi

Protein namesi
Submitted name:
Glutamate receptor ionotropic, NMDA 3AImported
Gene namesi
Name:Grin3aImported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 5

Organism-specific databases

RGDi621704. Grin3a.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei443 – 463HelicalSequence analysisAdd BLAST21
Transmembranei484 – 502HelicalSequence analysisAdd BLAST19
Transmembranei514 – 537HelicalSequence analysisAdd BLAST24
Transmembranei702 – 723HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Cell membraneSAAS annotation, Membrane

Expressioni

Gene expression databases

BgeeiENSRNOG00000005723.

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini324 – 678PBPeInterPro annotationAdd BLAST355
Domaini325 – 390Lig_chan-Glu_bdInterPro annotationAdd BLAST66

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili853 – 887Sequence analysisAdd BLAST35

Sequence similaritiesi

Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. [View classification]SAAS annotation

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG1053. Eukaryota.
ENOG410XNUR. LUCA.
GeneTreeiENSGT00760000119186.
OMAiTQFGVMP.
OrthoDBiEOG091G00PT.

Family and domain databases

InterProiView protein in InterPro
IPR019594. Glu/Gly-bd.
IPR001508. Iono_rcpt_met.
IPR001320. Iontro_rcpt.
IPR028082. Peripla_BP_I.
PfamiView protein in Pfam
PF00060. Lig_chan. 1 hit.
PF10613. Lig_chan-Glu_bd. 1 hit.
PRINTSiPR00177. NMDARECEPTOR.
SMARTiView protein in SMART
SM00918. Lig_chan-Glu_bd. 1 hit.
SM00079. PBPe. 1 hit.
SUPFAMiSSF53822. SSF53822. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A096MIS4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
QNPLHLQLSL ENSLSSDADV TVSILTMNNW YNFSLLLCQE DWNITDFLLL
60 70 80 90 100
TENNSKFHLE SVINITANLS STKDLLSFLQ VQMDNIRNST PTMVMFGCDM
110 120 130 140 150
DSIRQIFEMS TQFGLSPPEL HWVLGDSQNV EELRTEGLPL GLIAHGKTTQ
160 170 180 190 200
SVFEYYVQDA MELVARAVAT ATMIQPELAL LPSTMNCMDV KTTNLTSGQY
210 220 230 240 250
LSRFLANTTF RGLSGSIKVK GSTIISSENN FFIWNLQHDP MGKPMWTRLG
260 270 280 290 300
SWQGGRIVMD SGIWPEQAQR HKTHFQHPNK LHLRVVTLIE HPFVFTREVD
310 320 330 340 350
DEGLCPAGQL CLDPMTNDSS MLDRLFSSLH SSNDTVPIKF KKCCYGYCID
360 370 380 390 400
LLEQLAEDMN FDFDLYIVGD GKYGAWKNGH WTGLVGDLLS GTANMAVTSF
410 420 430 440 450
SINTARSQVI DFTSPFFSTS LGILVRTRDT AAPIGAFMWP LHWTMWLGIF
460 470 480 490 500
VALHITAIFL TLYEWKSPFG MTPKGRNRNK VFSFSSALNV CYALLFGRTA
510 520 530 540 550
AIKPPKCWTG RFLMNLWAIF CMFCLSTYTA NLAAVMVGEK IYEELSGIHD
560 570 580 590 600
PKLHHPSQGF RFGTVRESSA EDYVRQSFPE MHEYMRRYNV PATPDGVQYL
610 620 630 640 650
KNDPEKLDAF IMDKALLDYE VSIDADCKLL TVGKPFAIEG YGIGLPPNSP
660 670 680 690 700
LTSNISELIS QYKSHGFMDV LHDKWYKVVP CGKRSFAVTE TLQMGIKHFS
710 720 730 740 750
GLFVLLCIGF GLSILTTIGE HIVHRLLLPR IKNKSKLQYW LHTSQRFHRA
760 770 780 790 800
LNTSFVEEKQ PRSKTKRVEK SRWRRWTCKT EGDSELSLFP RSNLGPQQLM
810 820 830 840 850
VWNTSNLSHD NQRKYIFNDE EGQNQLGTQA HQDIPLPQRR RELPASLTTN
860 870 880 890 900
GKADSLNVTR SSVIQELSEL EKQIQVIRQE LQLAVSRKTE LEEYQKTNRT

CES
Length:903
Mass (Da):102,650
Last modified:July 22, 2015 - v2
Checksum:i50AE58817213B1F9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07048153 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSRNOT00000007957; ENSRNOP00000007957; ENSRNOG00000005723.

Similar proteinsi

Entry informationi

Entry nameiA0A096MIS4_RAT
AccessioniPrimary (citable) accession number: A0A096MIS4
Entry historyiIntegrated into UniProtKB/TrEMBL: November 26, 2014
Last sequence update: July 22, 2015
Last modified: January 31, 2018
This is version 24 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported