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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Prochlorococcus sp. MIT 0801
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotationSAAS annotation

Pathwayi: gluconeogenesis

This protein is involved in the pathway gluconeogenesis, which is part of Carbohydrate biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway gluconeogenesis and in Carbohydrate biosynthesis.

Pathwayi: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose.UniRule annotationSAAS annotation
Proteins known to be involved in the 4 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Glucose-6-phosphate isomerase (pgi)
  3. no protein annotated in this organism
  4. no protein annotated in this organism
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei351UniRule annotation1
Active sitei453UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomeraseUniRule annotationSAAS annotationImported
Biological processGluconeogenesisUniRule annotationSAAS annotation, GlycolysisUniRule annotationSAAS annotation

Enzyme and pathway databases

UniPathwayiUPA00109; UER00181.
UPA00138.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
ORF Names:EW15_1009Imported
OrganismiProchlorococcus sp. MIT 0801Imported
Taxonomic identifieri1501269 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaSynechococcalesProchloraceaeProchlorococcus
Proteomesi
  • UP000029485 Componenti: Chromosome

Subcellular locationi

A0A089PAB9:
  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotationSAAS annotation

Phylogenomic databases

KOiK01810.

Family and domain databases

CDDicd05015. SIS_PGI_1. 1 hit.
cd05016. SIS_PGI_2. 1 hit.
HAMAPiMF_00473. G6P_isomerase. 1 hit.
InterProiView protein in InterPro
IPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
IPR035476. SIS_PGI_1.
IPR035482. SIS_PGI_2.
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiView protein in Pfam
PF00342. PGI. 2 hits.
PRINTSiPR00662. G6PISOMERASE.
PROSITEiView protein in PROSITE
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A089PAB9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNNKDKWRRY CDLLYSNDSL GFWLDISRMD VETTDFEDFN EMYSKAFDAL
60 70 80 90 100
ESLENGSIAN IDESRQVGHY WLRNPKVAPS PDISDSITKE IQDISKFGAS
110 120 130 140 150
ILNGEITNSD GKKYTDVFWI GIGGSGLGPL LIKESFKRET IGLDLHFLDN
160 170 180 190 200
VDPEGISHKL NSILPNLDST LFVVVSKSGG TPEPLIGMEQ AMKFVRDNNQ
210 220 230 240 250
NWSSRAIAIT SKGSKLDVLA DNENWLDIFD LPDWVGGRTS ITGAVGLLPA
260 270 280 290 300
ALIGADIDKF LNGASQMDAL TRVKDIKNNP AALLSLAWFK SGNGKGLRDM
310 320 330 340 350
VVLPYRDRLE VFSRYLQQLV MESLGKKYDR DEIQVNQGIA VYGNKGSTDQ
360 370 380 390 400
HAYVQQLRDG IDNFFVNFIE ILHDPLEIVE VKNKRPGDYL SGFLQGTRSA
410 420 430 440 450
LTEGGRQNLT ITFKSFDESS LGALIALFER AVSLYAELIN VNAYNQPGVE
460 470 480 490 500
AGKKAATKII KLQKEIEELL ADGKQRTLNE INDELSSEST ESIYLILRKL
510 520
SENSEHYSMI GNQSNPDKLI ILKT
Length:524
Mass (Da):58,444
Last modified:November 26, 2014 - v1
Checksum:i5CD4EE9F734B42C8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP007754 Genomic DNA. Translation: AIQ97101.1.

Genome annotation databases

EnsemblBacteriaiAIQ97101; AIQ97101; EW15_1009.
KEGGiprm:EW15_1009.

Similar proteinsi

Entry informationi

Entry nameiA0A089PAB9_9PROC
AccessioniPrimary (citable) accession number: A0A089PAB9
Entry historyiIntegrated into UniProtKB/TrEMBL: November 26, 2014
Last sequence update: November 26, 2014
Last modified: September 27, 2017
This is version 24 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported