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Protein
Submitted name:

Optineurin

Gene
N/A
Organism
Poecilia formosa (Amazon molly) (Limia formosa)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
OptineurinImported
OrganismiPoecilia formosa (Amazon molly) (Limia formosa)Imported
Taxonomic identifieri48698 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiNeoteleosteiAcanthomorphataOvalentariaAtherinomorphaeCyprinodontiformesPoeciliidaePoeciliinaePoecilia
Proteomesi
  • UP000028760 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliA0A087Y6I8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini494 – 524CCHC NOA-typeInterPro annotationAdd BLAST31

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili22 – 49Sequence analysisAdd BLAST28
Coiled coili61 – 95Sequence analysisAdd BLAST35
Coiled coili107 – 137Sequence analysisAdd BLAST31
Coiled coili186 – 220Sequence analysisAdd BLAST35
Coiled coili248 – 320Sequence analysisAdd BLAST73
Coiled coili335 – 403Sequence analysisAdd BLAST69
Coiled coili428 – 462Sequence analysisAdd BLAST35

Keywords - Domaini

Coiled coilSequence analysis, Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

GeneTreeiENSGT00530000063808
OMAiLQVTTLF
OrthoDBiEOG091G0576

Family and domain databases

InterProiView protein in InterPro
IPR032419 CC2-LZ_dom
IPR021063 NEMO_N
IPR034735 NEMO_ZF
IPR032939 Optineurin
PANTHERiPTHR31553:SF2 PTHR31553:SF2, 1 hit
PfamiView protein in Pfam
PF16516 CC2-LZ, 1 hit
PF11577 NEMO, 1 hit
PROSITEiView protein in PROSITE
PS51801 ZF_CCHC_NOA, 1 hit

Sequencei

Sequence statusi: Complete.

A0A087Y6I8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASGGPMVNG DVPRPPGQLG TLEETVQQMN ILIQENRDLK EALRQTNLTM
60 70 80 90 100
KERFEGLTVW KEKQRQEKDF LEKRLEEARR CIETLTVQNQ ELSKRPEAGG
110 120 130 140 150
GAQSAEVDAL RAQVARLQAE KNDLVALNSE LQLKAEQGAE EDSFIEIIRV
160 170 180 190 200
SDAGVEDVNQ TCGSERIRRP DLSMTTSRQE NEEATVSRLL QSLRNETQRC
210 220 230 240 250
EQLQSELQVC TARIQDLEKN YKVEKTMKTT QTEVKEDPAK EEKAASEVEN
260 270 280 290 300
LKSQVRTLFR DLQQAQSKLD EAEGMKKNLQ DRCREVEQDV ATLKAQLLEK
310 320 330 340 350
QAVQAENERL KLQLGSLQAQ GQLEQKKADD DRNNLAQLKD AYTKLFEDYN
360 370 380 390 400
ELKEEKKRKE SHMVERNLVE DLQQRLTAAE EALAVKQNKI DDMKQEMFQK
410 420 430 440 450
EKELETISVF QAQAEVYSSD FYAERAAREK LHEEKERLAA QLEFIKKQNT
460 470 480 490 500
QLQQDMDSLG RRSLNEMQRR HGSSVSGSHG PDASLVGRGT DWNQGNIPEH
510 520
ACPKCNEILP DLDSLQIHIM DCIN
Length:524
Mass (Da):59,907
Last modified:November 26, 2014 - v2
Checksum:i7805A70C974CFCBD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AYCK01014253 Genomic DNA No translation available.
RefSeqiXP_007571716.1, XM_007571654.2
XP_016537025.1, XM_016681539.1

Genome annotation databases

EnsembliENSPFOT00000013660; ENSPFOP00000013641; ENSPFOG00000013588
GeneIDi103151533

Similar proteinsi

Entry informationi

Entry nameiA0A087Y6I8_POEFO
AccessioniPrimary (citable) accession number: A0A087Y6I8
Entry historyiIntegrated into UniProtKB/TrEMBL: October 29, 2014
Last sequence update: November 26, 2014
Last modified: March 28, 2018
This is version 23 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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