Uncharacterized protein

Functionⁱ

GO - Molecular functionⁱ

cysteine-type endopeptidase activity Source: InterPro

Complete GO annotation...

GO - Biological processⁱ

apoptotic process Source: Ensembl
cellular response to antibiotic Source: Ensembl
cellular response to retinoic acid Source: Ensembl
cellular response to xenobiotic stimulus Source: Ensembl
positive regulation of apoptotic process Source: Ensembl
regulation of collateral sprouting in absence of injury Source: Ensembl

Complete GO annotation...

Keywordsⁱ

Molecular function	Hydrolase, Protease, Thiol proteaseSAAS annotation

Molecular function

Hydrolase, Protease, Thiol proteaseSAAS annotation

Protein family/group databases

MEROPS protease database More...MEROPSⁱ	C14.003.

MEROPSⁱ

C14.003.

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: Uncharacterized proteinImported
Organismⁱ	Poecilia formosa (Amazon molly) (Limia formosa)Imported
Taxonomic identifierⁱ	48698 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Actinopterygii › Actinopteri › Neopterygii › Teleostei › Osteoglossocephalai › Clupeocephala › Euteleosteomorpha › Neoteleostei › Eurypterygia › Ctenosquamata › Acanthomorphata › Euacanthomorphacea › Percomorphaceae › Ovalentaria › Atherinomorphae › Cyprinodontiformes › Cyprinodontoidei › Poeciliidae › Poeciliinae › Poecilia
Proteomesⁱ	UP000028760 Componentⁱ: Unassembled WGS sequence

Subcellular locationⁱ

GO - Cellular componentⁱ

cytoplasm Source: InterPro

Complete GO annotation...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	52 – 176	CASPASE_P20InterPro annotationAdd BLAST		125
Domainⁱ	188 – 282	CASPASE_P10InterPro annotationAdd BLAST		95

Sequence similaritiesⁱ

Belongs to the peptidase C14A family.UniRule annotationSAAS annotation

Phylogenomic databases

Ensembl GeneTree More...GeneTreeⁱ	ENSGT00760000118912.
OMAⁱ	KPNGNKA.
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G05YD.

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd00032. CASc. 1 hit.
InterProⁱ	View protein in InterPro IPR029030. Caspase-like_dom. IPR015470. Caspase_3. IPR033139. Caspase_cys_AS. IPR016129. Caspase_his_AS. IPR002138. Pept_C14_p10. IPR001309. Pept_C14_p20. IPR015917. Pept_C14A.
PANTHERⁱ	PTHR10454:SF178. PTHR10454:SF178. 1 hit.
PRINTSⁱ	PR00376. IL1BCENZYME.
SMARTⁱ	View protein in SMART SM00115. CASc. 1 hit.
SUPFAMⁱ	SSF52129. SSF52129. 1 hit.
PROSITEⁱ	View protein in PROSITE PS01122. CASPASE_CYS. 1 hit. PS01121. CASPASE_HIS. 1 hit. PS50207. CASPASE_P10. 1 hit. PS50208. CASPASE_P20. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Complete.

A0A087XNM2-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MSARRPGPEG DTTDARQDNG KQPAGSLSAP SPMDVDAKPH SHSFRYSLRY 
        60         70         80         90        100
PSIGQCIIIN NKNFDRRTGM NQRNGTDVDA ANVCKVFTKL GYAVKIYNDQ 
       110        120        130        140        150
TTDQMMKILS ATSMHDHSNS ASFVCVLLSH GDEGVIFGTD GPVQLQSLTS 
       160        170        180        190        200
LYRGDRCKTL VGKPKLFFIQ ACRGTDLDPG VEADSADETA KIPVEADFLY 
       210        220        230        240        250
AFSTAPGYYS WRNTMTGSWF IQSLCDMISK YGRELELLHI MTRVNHKVAV 
       260        270        280 
EFESVSNSPG FNARKQIPCI VSMLTKEMYF CP

Length:282

Mass (Da):31,253

Last modified:November 26, 2014 - v2

Checksum:ⁱ1784A5DE1E364D13

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AYCK01003560 Genomic DNA. No translation available.
NCBI Reference Sequences More...RefSeqⁱ	XP_007549682.1. XM_007549620.2.

Genome annotation databases

Ensemblⁱ	ENSPFOT00000007387; ENSPFOP00000007375; ENSPFOG00000007411. ENSPFOT00000029246; ENSPFOP00000028761; ENSPFOG00000007411.
GeneIDⁱ	103136385.

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AYCK01003560 Genomic DNA. No translation available.
NCBI Reference Sequences More...RefSeqⁱ	XP_007549682.1. XM_007549620.2.

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein family/group databases

MEROPS protease database More...MEROPSⁱ	C14.003.

MEROPSⁱ

C14.003.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSPFOT00000007387; ENSPFOP00000007375; ENSPFOG00000007411. ENSPFOT00000029246; ENSPFOP00000028761; ENSPFOG00000007411.
GeneIDⁱ	103136385.

Organism-specific databases

CTDⁱ	836.

CTDⁱ

836.

Phylogenomic databases

Ensembl GeneTree More...GeneTreeⁱ	ENSGT00760000118912.
OMAⁱ	KPNGNKA.
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G05YD.

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd00032. CASc. 1 hit.
InterProⁱ	View protein in InterPro IPR029030. Caspase-like_dom. IPR015470. Caspase_3. IPR033139. Caspase_cys_AS. IPR016129. Caspase_his_AS. IPR002138. Pept_C14_p10. IPR001309. Pept_C14_p20. IPR015917. Pept_C14A.
PANTHERⁱ	PTHR10454:SF178. PTHR10454:SF178. 1 hit.
PRINTSⁱ	PR00376. IL1BCENZYME.
SMARTⁱ	View protein in SMART SM00115. CASc. 1 hit.
SUPFAMⁱ	SSF52129. SSF52129. 1 hit.
PROSITEⁱ	View protein in PROSITE PS01122. CASPASE_CYS. 1 hit. PS01121. CASPASE_HIS. 1 hit. PS50207. CASPASE_P10. 1 hit. PS50208. CASPASE_P20. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	A0A087XNM2_POEFO
Accessionⁱ	A0A087XNM2Primary (citable) accession number: A0A087XNM2
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	October 29, 2014
	Last sequence update:	November 26, 2014
	Last modified:	June 7, 2017
	This is version 20 of the entry and version 2 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termⁱ

Complete proteome, Reference proteomeImported

UniProtKB - A0A087XNM2 (A0A087XNM2_POEFO)

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Keywordsⁱ

Protein family/group databases

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

Family & Domainsⁱ

Domains and Repeats

Sequence similaritiesⁱ

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Sequence databases

Genome annotation databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Protein family/group databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Family and domain databases

Entry informationⁱ

Miscellaneousⁱ

Caution

Keywords - Technical termⁱ

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - A0A087XNM2 (A0A087XNM2_POEFO)

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Uncharacterized protein

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Protein family/group databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein family/group databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Caution

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ