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Protein
Submitted name:

Pyrroline-5-carboxylate reductase 2

Gene

PYCR2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Pyrroline-5-carboxylate reductase 2Imported
Gene namesi
Name:PYCR2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

EuPathDBiHostDB:ENSG00000143811.16.
HGNCiHGNC:30262. PYCR2.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000143811.

PTM / Processingi

Proteomic databases

PaxDbiA0A087WZF0.
PeptideAtlasiA0A087WZF0.

Expressioni

Gene expression databases

BgeeiENSG00000143811.
ExpressionAtlasiA0A087WZF0. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliA0A087WZF0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini9 – 62F420_oxidoredInterPro annotationAdd BLAST54
Domaini128 – 157P5CR_dimerInterPro annotationAdd BLAST30

Phylogenomic databases

eggNOGiKOG3124. Eukaryota.
COG0345. LUCA.
GeneTreeiENSGT00390000007443.

Family and domain databases

InterProiView protein in InterPro
IPR008927. 6-PGluconate_DH_C-like.
IPR016040. NAD(P)-bd_dom.
IPR028939. P5C_Rdtase_cat_N.
IPR029036. P5CR_dimer.
IPR000304. Pyrroline-COOH_reductase.
PANTHERiPTHR11645. PTHR11645. 1 hit.
PfamiView protein in Pfam
PF03807. F420_oxidored. 1 hit.
PF14748. P5CR_dimer. 1 hit.
SUPFAMiSSF48179. SSF48179. 1 hit.
SSF51735. SSF51735. 1 hit.

Sequencei

Sequence statusi: Fragment.

A0A087WZF0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNLPTVSALR KMGVNLTRSN KETVKHSDVL FLAVKPHIIP FILDEIGADV
60 70 80 90 100
QARHIVVSCA AGVTISSVEK KLMAFQPAPK VIRCMTNTPV VVQEGATVYA
110 120 130 140 150
TGTHALVEDG QLLEQLMSSV GFCTEVEEDL IDAVTGLSGS GPAYAFMALD

ALADGGV
Length:157
Mass (Da):16,568
Last modified:October 29, 2014 - v1
Checksum:i5ED42D85A4C5A1A5
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei157Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL117348 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000489681; ENSP00000482614; ENSG00000143811.
UCSCiuc057pxt.1. human.

Similar proteinsi

Entry informationi

Entry nameiA0A087WZF0_HUMAN
AccessioniPrimary (citable) accession number: A0A087WZF0
Entry historyiIntegrated into UniProtKB/TrEMBL: October 29, 2014
Last sequence update: October 29, 2014
Last modified: September 27, 2017
This is version 22 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported