UniProtKB - A0A087WWD4 (A0A087WWD4_HUMAN)
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Protein
Submitted name:
Neural cell adhesion molecule 1
Gene
NCAM1
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: Neural cell adhesion molecule 1Imported |
Gene namesi | Name:NCAM1Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000149294.16 |
HGNCi | HGNC:7656 NCAM1 |
Subcellular locationi
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 749 – 772 | HelicalSequence analysisAdd BLAST | 24 |
Keywords - Cellular componenti
MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 19 | Sequence analysisAdd BLAST | 19 | |
ChainiPRO_5001831984 | 20 – 884 | Sequence analysisAdd BLAST | 865 |
Proteomic databases
PeptideAtlasi | A0A087WWD4 |
PRIDEi | A0A087WWD4 |
Expressioni
Gene expression databases
Bgeei | ENSG00000149294 |
ExpressionAtlasi | A0A087WWD4 baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 20 – 111 | Ig-likeInterPro annotationAdd BLAST | 92 | |
Domaini | 116 – 189 | Ig-likeInterPro annotationAdd BLAST | 74 | |
Domaini | 212 – 301 | Ig-likeInterPro annotationAdd BLAST | 90 | |
Domaini | 308 – 439 | Ig-likeInterPro annotationAdd BLAST | 132 | |
Domaini | 442 – 527 | Ig-likeInterPro annotationAdd BLAST | 86 | |
Domaini | 535 – 634 | Fibronectin type-IIIInterPro annotationAdd BLAST | 100 | |
Domaini | 637 – 732 | Fibronectin type-IIIInterPro annotationAdd BLAST | 96 |
Keywords - Domaini
RepeatSAAS annotation, SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisPhylogenomic databases
eggNOGi | ENOG410IQJI Eukaryota ENOG410XTGB LUCA |
GeneTreei | ENSGT00910000144011 |
Family and domain databases
CDDi | cd00063 FN3, 2 hits |
Gene3Di | 2.60.40.106 hits |
InterProi | View protein in InterPro IPR003961 FN3_dom IPR036116 FN3_sf IPR007110 Ig-like_dom IPR036179 Ig-like_dom_sf IPR013783 Ig-like_fold IPR013098 Ig_I-set IPR003599 Ig_sub IPR003598 Ig_sub2 IPR033019 Ncam1 IPR009138 Neural_cell_adh |
PANTHERi | PTHR44059:SF2 PTHR44059:SF2, 2 hits |
Pfami | View protein in Pfam PF00041 fn3, 2 hits PF07679 I-set, 3 hits |
PRINTSi | PR01838 NCAMFAMILY |
SMARTi | View protein in SMART SM00060 FN3, 2 hits SM00409 IG, 5 hits SM00408 IGc2, 5 hits |
SUPFAMi | SSF48726 SSF48726, 6 hits SSF49265 SSF49265, 1 hit |
PROSITEi | View protein in PROSITE PS50853 FN3, 2 hits PS50835 IG_LIKE, 5 hits |
i Sequence
Sequence statusi: Complete.
A0A087WWD4-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLQTKDLIWT LFFLGTAVSL QVDIVPSQGE ISVGESKFFL CQVAGDAKDK
60 70 80 90 100
DISWFSPNGE KLTPNQQRIS VVWNDDSSST LTIYNANIDD AGIYKCVVTG
110 120 130 140 150
EDGSESEATV NVKIFQKLMF KNAPTPQEFR EGEDAVIVCD VVSSLPPTII
160 170 180 190 200
WKHKGRDVIL KKDVRFIVLS NNYLQIRGIK KTDEGTYRCE GRILARGEIN
210 220 230 240 250
FKDIQVIVNV PPTIQARQNI VNATANLGQS VTLVCDAEGF PEPTMSWTKD
260 270 280 290 300
GEQIEQEEDD EKYIFSDDSS QLTIKKVDKN DEAEYICIAE NKAGEQDATI
310 320 330 340 350
HLKVFAKPKI TYVENQTAME LEEQVTLTCE ASGDPIPSIT WRTSTRNISS
360 370 380 390 400
EEKASWTRPE KQEVHAPWNW QVGRQKGQAG SAGFPGSHET LDGHMVVRSH
410 420 430 440 450
ARVSSLTLKS IQYTDAGEYI CTASNTIGQD SQSMYLEVQY APKLQGPVAV
460 470 480 490 500
YTWEGNQVNI TCEVFAYPSA TISWFRDGQL LPSSNYSNIK IYNTPSASYL
510 520 530 540 550
EVTPDSENDF GNYNCTAVNR IGQESLEFIL VQADTPSSPS IDQVEPYSST
560 570 580 590 600
AQVQFDEPEA TGGVPILKYK AEWRAVGEEV WHSKWYDAKE ASMEGIVTIV
610 620 630 640 650
GLKPETTYAV RLAALNGKGL GEISAASEFK TQPVQGEPSA PKLEGQMGED
660 670 680 690 700
GNSIKVNLIK QDDGGSPIRH YLVRYRALSS EWKPEIRLPS GSDHVMLKSL
710 720 730 740 750
DWNAEYEVYV VAENQQGKSK AAHFVFRTSA QPTAIPANGS PTSGLSTGAI
760 770 780 790 800
VGILIVIFVL LLVVVDITCY FLNKCGLFMC IAVNLCGKAG PGAKGKDMEE
810 820 830 840 850
GKAAFSKDES KEPIVEVRTE EERTPNHDGG KHTEPNETTP LTEPEKGPVE
860 870 880
AKPECQETET KPAPAEVKTV PNDATQTKEN ESKA
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AP000802 Genomic DNA No translation available. AP000999 Genomic DNA No translation available. AP002853 Genomic DNA No translation available. FP884230 Genomic DNA No translation available. KF455513 Genomic DNA No translation available. KF455515 Genomic DNA No translation available. KF455518 Genomic DNA No translation available. KF511120 Genomic DNA No translation available. |
RefSeqi | NP_001229536.1, NM_001242607.1 |
UniGenei | Hs.503878 Hs.711235 Hs.733031 |
Genome annotation databases
Ensembli | ENST00000619839; ENSP00000480132; ENSG00000149294 |
GeneIDi | 4684 |
UCSCi | uc058hjr.1 human |
Similar proteinsi
Entry informationi
Entry namei | A0A087WWD4_HUMAN | |
Accessioni | A0A087WWD4Primary (citable) accession number: A0A087WWD4 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 29, 2014 |
Last sequence update: | October 29, 2014 | |
Last modified: | March 28, 2018 | |
This is version 31 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |