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Protein
Submitted name:

Aryl hydrocarbon receptor nuclear translocator 2

Gene

ARNT2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingSAAS annotation
Biological processTranscription, Transcription regulationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Aryl hydrocarbon receptor nuclear translocator 2Imported
Gene namesi
Name:ARNT2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 15

Organism-specific databases

EuPathDBiHostDB:ENSG00000172379.18.
HGNCiHGNC:16876. ARNT2.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusSAAS annotation

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000172379.

PTM / Processingi

Proteomic databases

PaxDbiA0A087WVE9.

Expressioni

Gene expression databases

BgeeiENSG00000172379.
ExpressionAtlasiA0A087WVE9. baseline and differential.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

IntActiA0A087WVE9. 11 interactors.

Structurei

3D structure databases

ProteinModelPortaliA0A087WVE9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini63 – 116BHLHInterPro annotationAdd BLAST54
Domaini134 – 209PASInterPro annotationAdd BLAST76
Domaini342 – 393PASInterPro annotationAdd BLAST52

Keywords - Domaini

RepeatSAAS annotation

Phylogenomic databases

eggNOGiENOG410IQ5Q. Eukaryota.
ENOG410XS5S. LUCA.
GeneTreeiENSGT00760000118788.

Family and domain databases

CDDicd00083. HLH. 1 hit.
cd00130. PAS. 2 hits.
Gene3Di4.10.280.10. 1 hit.
InterProiView protein in InterPro
IPR011598. bHLH_dom.
IPR036638. HLH_DNA-bd_sf.
IPR001067. Nuc_translocat.
IPR001610. PAC.
IPR000014. PAS.
IPR035965. PAS-like_dom_sf.
IPR013767. PAS_fold.
IPR013655. PAS_fold_3.
PfamiView protein in Pfam
PF00010. HLH. 1 hit.
PF00989. PAS. 1 hit.
PF08447. PAS_3. 1 hit.
PRINTSiPR00785. NCTRNSLOCATR.
SMARTiView protein in SMART
SM00353. HLH. 1 hit.
SM00086. PAC. 1 hit.
SM00091. PAS. 2 hits.
SUPFAMiSSF47459. SSF47459. 1 hit.
SSF55785. SSF55785. 4 hits.
TIGRFAMsiTIGR00229. sensory_box. 1 hit.
PROSITEiView protein in PROSITE
PS50888. BHLH. 1 hit.
PS50112. PAS. 2 hits.

Sequencei

Sequence statusi: Complete.

A0A087WVE9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATPAAVNPP EMASDIPGSV TLPVAPMAAT GQVRMAGAMP ARGGKRRSGM
60 70 80 90 100
DFDDEDGEGP SKFSRENHSE IERRRRNKMT QYITELSDMV PTCSALARKP
110 120 130 140 150
DKLTILRMAV SHMKSMRGTG NKSTDGAYKP SFLTEQELKH LILEAADGFL
160 170 180 190 200
FVVAAETGRV IYVSDSVTPV LNQPQSEWFG STLYEQVHPD DVEKLREQLC
210 220 230 240 250
TSENSMTGRI LDLKTGTVKK EGQQSSMRMC MGSRRSFICR MRCGNAPLDH
260 270 280 290 300
LPLNRITTMR KRFRNGLGPV KEGEAQYAVV HCTGYIKAWP PAGMTIPEED
310 320 330 340 350
ADVGQGSKYC LVAIGRLQVT SSPVCMDMNG MSVPTEFLSR HNSDGIITFV
360 370 380 390 400
DPRCISVIGY QPQDLLGKDI LEFCHPEDQS HLRESFQQVV KLKGQVLSVM
410 420 430 440 450
YRFRTKNREW MLIRTSSFTF QNPYSDEIEY IICTNTNVKQ LQQQQAELEV
460 470 480 490 500
HQRDGLSSYD LSQVPVPNLP AGVHEAGKSV EKADAIFSQE RDPRFAEMFA
510 520 530 540 550
GISASEKKMM SSASAAGTQQ IYSQGSPFPS GHSGKAFSSS VVHVPGVNDI
560 570 580 590 600
QSSSSTGQNM SQISRQLNQS QVAWTGSRPP FPGQQIPSQS SKTQSSPFGI
610 620 630 640 650
GTSHTYPADP SSYSPLSSPA TSSPSGNAYS SLANRTPGFA ESGQSSGQFQ
660 670 680 690 700
GRPSEVWSQW QSQHHGQQSG EQHSHQQPGQ TEVFQDMLPM PGDPRNEWWS
710
PHSRQHFRQP ISYARM
Length:716
Mass (Da):79,011
Last modified:October 29, 2014 - v1
Checksum:iC9E6600B6E1B7323
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC016705 Genomic DNA. No translation available.
AC108451 Genomic DNA. No translation available.
KF511219 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000622346; ENSP00000479393; ENSG00000172379.
UCSCiuc059mjr.1. human.

Similar proteinsi

Entry informationi

Entry nameiA0A087WVE9_HUMAN
AccessioniPrimary (citable) accession number: A0A087WVE9
Entry historyiIntegrated into UniProtKB/TrEMBL: October 29, 2014
Last sequence update: October 29, 2014
Last modified: October 25, 2017
This is version 28 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported