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Protein
Submitted name:

Cytochrome P450 4A22

Gene

CYP4A22

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionMonooxygenaseUniRule annotation, Oxidoreductase
LigandHemeUniRule annotation, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Cytochrome P450 4A22Imported
Gene namesi
Name:CYP4A22Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

EuPathDBiHostDB:ENSG00000162365.11.
HGNCiHGNC:20575. CYP4A22.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei12 – 32HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000162365.

PTM / Processingi

Proteomic databases

PaxDbiA0A087WUY4.
PeptideAtlasiA0A087WUY4.

Expressioni

Gene expression databases

BgeeiENSG00000162365.
ExpressionAtlasiA0A087WUY4. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliA0A087WUY4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome P450 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG0157. Eukaryota.
COG2124. LUCA.
GeneTreeiENSGT00900000140829.
OMAiEVATECD.
OrthoDBiEOG091G06KN.

Family and domain databases

Gene3Di1.10.630.10. 1 hit.
InterProiView protein in InterPro
IPR001128. Cyt_P450.
IPR017972. Cyt_P450_CS.
IPR002401. Cyt_P450_E_grp-I.
IPR036396. Cyt_P450_sf.
PfamiView protein in Pfam
PF00067. p450. 1 hit.
PRINTSiPR00463. EP450I.
PR00385. P450.
SUPFAMiSSF48264. SSF48264. 1 hit.
PROSITEiView protein in PROSITE
PS00086. CYTOCHROME_P450. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A087WUY4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSVSVLSPSR RLGGVSGILQ VTSLLILLLL LIKAAQLYLH RQWLLKALQQ
60 70 80 90 100
FPCPPSHWLF GHIQEFQHDQ ELQRIQERVK TFPSACPYWI WGGKVRVQLY
110 120 130 140 150
DPDYMKVILG RSDPKSHGSY KFLAPRIGYG LLLLNGQTWF QHRRMLTPAF
160 170 180 190 200
HNDILKPYVG LMADSVRVML DKWEELLGQD SPLEVFQHVS LMTLDTIMKS
210 220 230 240 250
AFSHQGSIQV DRNSQSYIQA ISDLNSLVFC CMRNAFHEND TIYSLTSAGR
260 270 280 290 300
WTHRACQLAH QHTGDQVIQL RKAQLQKEGE LEKIKRKRHL DFLDILLLAK
310 320 330 340 350
MENGSILSDK DLRAEVDTFM FEGHDTTASG ISWILYALAT HPKHQERCRE
360 370 380 390 400
EIHGLLGDGA SITWNHLDQM PYTTMCIKEA LRLYPPVPGI GRELSTPVTF
410 420 430 440 450
PDGRSLPKGI MVLLSIYGLH HNPKVWPNLE VFDPSRFAPG SAQHSHAFLP
460 470 480 490 500
FSGGSRNCIG KQFAMNQLKV ARALTLLRFE LLPDPTRIPI PMARLVLKSK
510 520
NGIHLRLRRL PNPCEDKDQL
Length:520
Mass (Da):59,303
Last modified:October 29, 2014 - v1
Checksum:i908726791B607CAB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL135960 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000620131; ENSP00000479019; ENSG00000162365.
UCSCiuc057ghi.1. human.

Similar proteinsi

Entry informationi

Entry nameiA0A087WUY4_HUMAN
AccessioniPrimary (citable) accession number: A0A087WUY4
Entry historyiIntegrated into UniProtKB/TrEMBL: October 29, 2014
Last sequence update: October 29, 2014
Last modified: October 25, 2017
This is version 22 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported