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Protein
Submitted name:

Mothers against decapentaplegic homolog 4

Gene

SMAD4

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Mothers against decapentaplegic homolog 4Imported
Gene namesi
Name:SMAD4Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 18

Organism-specific databases

EuPathDBiHostDB:ENSG00000141646.13.
HGNCiHGNC:6770. SMAD4.

Subcellular locationi

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000141646.

PTM / Processingi

Proteomic databases

PaxDbiA0A087WUF3.
PeptideAtlasiA0A087WUF3.

Expressioni

Gene expression databases

BgeeiENSG00000141646.
ExpressionAtlasiA0A087WUF3. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliA0A087WUF3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini57 – 220MH2InterPro annotationAdd BLAST164

Phylogenomic databases

eggNOGiKOG3701. Eukaryota.
ENOG410XQKU. LUCA.
GeneTreeiENSGT00760000119091.

Family and domain databases

Gene3Di2.60.200.10. 1 hit.
InterProiView protein in InterPro
IPR013790. Dwarfin.
IPR017855. SMAD_dom-like.
IPR001132. SMAD_dom_Dwarfin-type.
IPR008984. SMAD_FHA_domain.
PANTHERiPTHR13703. PTHR13703. 1 hit.
PfamiView protein in Pfam
PF03166. MH2. 1 hit.
SMARTiView protein in SMART
SM00524. DWB. 1 hit.
SUPFAMiSSF49879. SSF49879. 1 hit.
PROSITEiView protein in PROSITE
PS51076. MH2. 1 hit.

Sequencei

Sequence statusi: Fragment.

A0A087WUF3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
XWTGSRTAPY TPNLPHHQNG HLQHHPPMPP HPGHYWPVHN ELAFQPPISN
60 70 80 90 100
HPAPEYWCSI AYFEMDVQVG ETFKVPSSCP IVTVDGYVDP SGGDRFCLGQ
110 120 130 140 150
LSNVHRTEAI ERARLHIGKG VQLECKGEGD VWVRCLSDHA VFVQSYYLDR
160 170 180 190 200
EAGRAPGDAV HKIYPSAYIK VFDLRQCHRQ MQQQAATAQA AAAAQAAAVA
210 220
GNIPGPGSVG GIAPAIKLNS
Length:220
Mass (Da):23,994
Last modified:October 29, 2014 - v1
Checksum:iECF55457F9292528
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC091551 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000611848; ENSP00000478613; ENSG00000141646.
UCSCiuc060pfl.1. human.

Similar proteinsi

Entry informationi

Entry nameiA0A087WUF3_HUMAN
AccessioniPrimary (citable) accession number: A0A087WUF3
Entry historyiIntegrated into UniProtKB/TrEMBL: October 29, 2014
Last sequence update: October 29, 2014
Last modified: September 27, 2017
This is version 15 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported