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Protein

Chromosomal replication initiator protein DnaA

Gene

dnaA

Organism
Candidatus Accumulibacter sp. BA-91
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.UniRule annotationSAAS annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi169 – 176ATPUniRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingUniRule annotationSAAS annotation
Biological processDNA replicationUniRule annotationSAAS annotation
LigandATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Chromosomal replication initiator protein DnaAUniRule annotationSAAS annotation
Gene namesi
Name:dnaAUniRule annotationImported
ORF Names:AW09_004473Imported
OrganismiCandidatus Accumulibacter sp. BA-91Imported
Taxonomic identifieri1454002 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaCandidatus Accumulibacter
Proteomesi
  • UP000020077 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini161 – 292AAAInterPro annotationAdd BLAST132
Domaini372 – 441Bac_DnaA_CInterPro annotationAdd BLAST70

Sequence similaritiesi

Belongs to the DnaA family.UniRule annotationSAAS annotation

Family and domain databases

CDDicd06571. Bac_DnaA_C. 1 hit.
Gene3Di1.10.1750.10. 1 hit.
HAMAPiMF_00377. DnaA_bact. 1 hit.
InterProiView protein in InterPro
IPR003593. AAA+_ATPase.
IPR001957. Chromosome_initiator_DnaA.
IPR020591. Chromosome_initiator_DnaA-like.
IPR018312. Chromosome_initiator_DnaA_CS.
IPR013317. DnaA.
IPR013159. DnaA_C.
IPR024633. DnaA_N_dom.
IPR027417. P-loop_NTPase.
IPR010921. Trp_repressor/repl_initiator.
PANTHERiPTHR30050:SF2. PTHR30050:SF2. 1 hit.
PfamiView protein in Pfam
PF00308. Bac_DnaA. 1 hit.
PF08299. Bac_DnaA_C. 1 hit.
PF11638. DnaA_N. 1 hit.
PRINTSiPR00051. DNAA.
SMARTiView protein in SMART
SM00382. AAA. 1 hit.
SM00760. Bac_DnaA_C. 1 hit.
SUPFAMiSSF48295. SSF48295. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00362. DnaA. 1 hit.
PROSITEiView protein in PROSITE
PS01008. DNAA. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A084Y6U3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSFWSSCLS QFEQELPPQQ FNTWIRPLRL EGDDDIARGL RLLAPNGFIL
60 70 80 90 100
KWVKERYLAR IEALASEYYS TPVNITLNLG ERTAVTGNDS SGPTGKTPPA
110 120 130 140 150
GTAAAVTTTS RKTSPVEKDR SGYEKTRLIA TFTFDNLVVG KANDLARAAA
160 170 180 190 200
RQVSISPGEA TYNPLFIYGG AGLGKTHLIH AIGNRIVELD PEKVVRYVHA
210 220 230 240 250
EDYYSDVVRA YQQKSFDVFK RYYRSLDVLL LDDVHFFNGK NRTQEEFFYV
260 270 280 290 300
FNALSEARKQ IVISSDTYPK NISGLEDRLI TRFDWGLTVQ IEPPETEMRV
310 320 330 340 350
AILKKKAEAE GVVLDDEVAF YVAKHLRSNV RELEGALKKV LAYSAFHGQG
360 370 380 390 400
ITLDLAKEAL KDVIGSVNRQ ITVDSIQKTV AEYFKLKVAD LFSKKRTRVI
410 420 430 440 450
VRPRQIAMWL AKNLTSQSYP SIGDAFGGRD HTTVLHAVRT IDDLRTKDNE
460
LNHDVHVLLQ VLKG
Length:464
Mass (Da):52,178
Last modified:October 29, 2014 - v1
Checksum:i5D48BA964D40582A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JDVG02000703 Genomic DNA. Translation: KFB70437.1.

Similar proteinsi

Entry informationi

Entry nameiA0A084Y6U3_9PROT
AccessioniPrimary (citable) accession number: A0A084Y6U3
Entry historyiIntegrated into UniProtKB/TrEMBL: October 29, 2014
Last sequence update: October 29, 2014
Last modified: October 25, 2017
This is version 23 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported