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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Pseudomonas aeruginosa
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetaseUniRule annotation, Ligase
Biological processProtein biosynthesisUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotationImported
ORF Names:AO964_24455Imported, AOY09_00551Imported, CAZ03_01365Imported, CDC04_23580Imported, PAMH19_2807Imported
OrganismiPseudomonas aeruginosaImported
Taxonomic identifieri287 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000043988 Componenti: Unassembled WGS sequence
  • UP000196885 Componenti: Unassembled WGS sequence
  • UP000194726 Componenti: Unassembled WGS sequence
  • UP000054840 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Monomer.UniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 91Arg_tRNA_synt_NInterPro annotationAdd BLAST89
Domaini471 – 587DALR_1InterPro annotationAdd BLAST117

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi127 – 137"HIGH" regionUniRule annotationAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C75. Bacteria.
COG0018. LUCA.

Family and domain databases

CDDicd00671. ArgRS_core. 1 hit.
Gene3Di3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth. 1 hit.
InterProiView protein in InterPro
IPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR036695. Arg-tRNA-synth_N_sf.
IPR035684. ArgRS_core.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_Ia_anticodon-bd.
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiView protein in Pfam
PF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
PRINTSiPR01038. TRNASYNTHARG.
SMARTiView protein in SMART
SM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiView protein in PROSITE
PS00178. AA_TRNA_LIGASE_I. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A080VJY5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKDTIRQLIQ QALDQLTADG TLPAGLTPDI QVENTKDRSH GDFASNIAMM
60 70 80 90 100
LAKPAGMKPR DLAARLVEAI PAHEQLAKVE IAGPGFLNFF QDHVWLAASL
110 120 130 140 150
DRALADERLG VRKAGPAQRV VIDLSSPNLA KEMHVGHLRS TIIGDAVARV
160 170 180 190 200
LEFLGDTVIR QNHVGDWGTQ FGMLLAYLEE QPVDAEAELH DLEVFYRAAK
210 220 230 240 250
KRFDESPEFA DRARELVVKL QAGDPDCLRL WTRFNEISLS HCQKVYDRLG
260 270 280 290 300
VKLSMADVMG ESAYNDDLAQ VVADLTAKGL LTEDNGALCV FLEEFKNAEG
310 320 330 340 350
NPLPVIVQKA GGGYLYATTD LAAMRYRHNV LHADRVLYFV DQRQALHFQQ
360 370 380 390 400
VFEVARRAGF VPAGMELEHM GFGTMNGADG RPFKTRDGGT VKLIDLLEEA
410 420 430 440 450
ESRAYALVKE RNEQRAERGE EPFDEVQLRE IGRVVGIDSV KYADLSKHRT
460 470 480 490 500
SDYSFNFELM LSFEGNTAPY LLYACTRVAS VFRKLGQGRE QLGGKIVLEQ
510 520 530 540 550
PQELALAAQL AQFGDLINNV ALKGVPHLLC AYLYELAGLF SSFYEHCPIL
560 570 580
TAEDPAQKDS RLRLAALTGR TLEQGLELLG LKTLERM
Length:587
Mass (Da):65,199
Last modified:October 29, 2014 - v1
Checksum:iA31AF6885B56D5FC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP012901 Genomic DNA. Translation: ALV75642.1.
CDAZ01000009 Genomic DNA. Translation: CEI13188.1.
LLOD01000066 Genomic DNA. Translation: KSH06723.1.
NFFO01000001 Genomic DNA. Translation: OTH87827.1.
NIPD01000102 Genomic DNA. Translation: OWJ12240.1.
RefSeqiWP_003110892.1. NZ_NRFH01000002.1.

Genome annotation databases

EnsemblBacteriaiCEI13188; CEI13188; PAMH19_2807.
KSH06723; KSH06723; AO964_24455.
PATRICifig|287.1481.peg.533.

Similar proteinsi

Entry informationi

Entry nameiA0A080VJY5_PSEAI
AccessioniPrimary (citable) accession number: A0A080VJY5
Entry historyiIntegrated into UniProtKB/TrEMBL: October 29, 2014
Last sequence update: October 29, 2014
Last modified: November 22, 2017
This is version 30 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported