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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Palaeococcus pacificus DY20341
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetaseUniRule annotationImported, Ligase
Biological processProtein biosynthesisUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
ORF Names:PAP_07045Imported
OrganismiPalaeococcus pacificus DY20341Imported
Taxonomic identifieri1343739 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePalaeococcus
Proteomesi
  • UP000027981 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini8 – 96Arg_tRNA_synt_NInterPro annotationAdd BLAST89
Domaini524 – 646DALR_1InterPro annotationAdd BLAST123

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili227 – 254Sequence analysisAdd BLAST28

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi134 – 144"HIGH" regionUniRule annotationAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

KOiK01887.
OrthoDBiPOG093Z013U.

Family and domain databases

CDDicd00671. ArgRS_core. 1 hit.
Gene3Di1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth. 1 hit.
InterProiView protein in InterPro
IPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR035684. ArgRS_core.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_Ia_anticodon-bd.
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiView protein in Pfam
PF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 2 hits.
PRINTSiPR01038. TRNASYNTHARG.
SMARTiView protein in SMART
SM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiView protein in PROSITE
PS00178. AA_TRNA_LIGASE_I. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A075LUI4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAYEDVKNEV KLILSEELKK MAEEKGVELK VEVLFDETPS MELGDFATTV
60 70 80 90 100
AFQLAKVFRK APRMIAQEIV EHIGDKLPDY IAKVEIAGAG YINFFLDYEK
110 120 130 140 150
FGKSAVEEIL EKGDSFGKSE IGKGKKVIVE HTSVNPTKPL HMGHARNSIL
160 170 180 190 200
GDTMARVMRA LGYNVEVQNY IDDLGIQFAQ VFWGYLNLKD EFEKLREELK
210 220 230 240 250
AKGVKENAID HVLGLLYVEV HKKMQENPEV EKKIRELMKK LEEGDNEIAE
260 270 280 290 300
KGRKLAEECV KAQMETTYRL NIAYDLLSWE SDIVRSGIFE EAYAMIEKNE
310 320 330 340 350
HFEWAKEGKY KGAFIMKLSH LFPDMENPDK VLIRSDGTAT YTGKDIAYHM
360 370 380 390 400
WKFGLVSADM LYKVWDKVPF EGKEHETWTT SKDGEKSDKF GKADVVINVI
410 420 430 440 450
GAEQKYPQKV VAYALKLLGY ENAYENFHHL AYEHVVRPEG SFSGRKGTWV
460 470 480 490 500
GFTVDEVLDE AFKRARALVE EKNPSLSDGE KDKIAEAVGI GAVRYNMIKY
510 520 530 540 550
SPEKVIVFRW DDALNFEGES APYVQYAHAR CASILRKAQS EGLTINVKDL
560 570 580 590 600
FEKADFSKLD AKEKELIKIL SKFPEIVKTV GMDIKPHLLA WYANEVAMTF
610 620 630 640
NKFYMALTVL KAEEGIREER LLLVLATKQV LKNVLSLMGI EAPEVM
Length:646
Mass (Da):73,597
Last modified:October 29, 2014 - v1
Checksum:i44C6936DB9E2410F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP006019 Genomic DNA. Translation: AIF69801.1.
RefSeqiWP_048165320.1. NZ_CP006019.1.

Genome annotation databases

EnsemblBacteriaiAIF69801; AIF69801; PAP_07045.
GeneIDi24842522.
KEGGippac:PAP_07045.

Similar proteinsi

Entry informationi

Entry nameiA0A075LUI4_9EURY
AccessioniPrimary (citable) accession number: A0A075LUI4
Entry historyiIntegrated into UniProtKB/TrEMBL: October 29, 2014
Last sequence update: October 29, 2014
Last modified: September 27, 2017
This is version 20 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported