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Protein

Cytochrome c oxidase subunit 1

Gene

COI

Organism
Artemia franciscana (Brine shrimp) (Artemia sanfranciscana)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.UniRule annotation

Catalytic activityi

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.UniRule annotation

Pathwayi: oxidative phosphorylation

This protein is involved in the pathway oxidative phosphorylation, which is part of Energy metabolism.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway oxidative phosphorylation and in Energy metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotation
Biological processElectron transport, Respiratory chainUniRule annotation, Transport
LigandCopperUniRule annotation, HemeUniRule annotation, Iron, Metal-binding

Enzyme and pathway databases

UniPathwayiUPA00705.

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c oxidase subunit 1UniRule annotation (EC:1.9.3.1UniRule annotation)
Gene namesi
Name:COIImported
Encoded oniMitochondrionImported
OrganismiArtemia franciscana (Brine shrimp) (Artemia sanfranciscana)Imported
Taxonomic identifieri6661 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaCrustaceaBranchiopodaAnostracaArtemiidaeArtemia

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei33 – 54HelicalSequence analysisAdd BLAST22
Transmembranei117 – 142HelicalSequence analysisAdd BLAST26
Transmembranei154 – 181HelicalSequence analysisAdd BLAST28

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membraneUniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 187COX1InterPro annotationAdd BLAST187

Sequence similaritiesi

Belongs to the heme-copper respiratory oxidase family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Family and domain databases

Gene3Di1.20.210.10. 1 hit.
InterProiView protein in InterPro
IPR023616. Cyt_c_oxase-like_su1_dom.
IPR036927. Cyt_c_oxase-like_su1_sf.
IPR000883. Cyt_C_Oxase_1.
PANTHERiPTHR10422. PTHR10422. 1 hit.
PfamiView protein in Pfam
PF00115. COX1. 1 hit.
PRINTSiPR01165. CYCOXIDASEI.
SUPFAMiSSF81442. SSF81442. 1 hit.
PROSITEiView protein in PROSITE
PS50855. COX1. 1 hit.

Sequencei

Sequence statusi: Fragment.

A0A075D7P7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
GTSLSMLIRA ELGQPGSLIG DEQVYNVIVT AHAFIMIFFM VMPILIGGFG
60 70 80 90 100
NWLVPIMLGA PDMAFPRLNN LSFWMLPPSL TLLLASSMVE SGAGTGWTVY
110 120 130 140 150
PPLSSAIAHA GPSVDLAIFS LHLAGVSSIL GAVNFITTII NMRPQSMSID
160 170 180
RMPLFVWAVG ITAVLLLLSL PVLAGAITML LTDRNLN
Length:187
Mass (Da):19,909
Last modified:October 29, 2014 - v1
Checksum:i2886E6482425E91D
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei187Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KF691154 Genomic DNA. Translation: AHH82089.1.
KF691155 Genomic DNA. Translation: AHH82090.1.
KF691156 Genomic DNA. Translation: AHH82091.1.
KF691160 Genomic DNA. Translation: AHH82095.1.
KF691161 Genomic DNA. Translation: AHH82096.1.
KF691163 Genomic DNA. Translation: AHH82098.1.
KF691164 Genomic DNA. Translation: AHH82099.1.
KF691165 Genomic DNA. Translation: AHH82100.1.
KF691173 Genomic DNA. Translation: AHH82108.1.
KF691174 Genomic DNA. Translation: AHH82109.1.
KF691175 Genomic DNA. Translation: AHH82110.1.
KF691176 Genomic DNA. Translation: AHH82111.1.
KF691177 Genomic DNA. Translation: AHH82112.1.
KF691178 Genomic DNA. Translation: AHH82113.1.
KF691179 Genomic DNA. Translation: AHH82114.1.
KF691180 Genomic DNA. Translation: AHH82115.1.
KF691181 Genomic DNA. Translation: AHH82116.1.
KF691182 Genomic DNA. Translation: AHH82117.1.
KF691184 Genomic DNA. Translation: AHH82119.1.
KF691185 Genomic DNA. Translation: AHH82120.1.
KF691186 Genomic DNA. Translation: AHH82121.1.
KF691190 Genomic DNA. Translation: AHH82125.1.
KF691191 Genomic DNA. Translation: AHH82126.1.
KF691192 Genomic DNA. Translation: AHH82127.1.
KF691193 Genomic DNA. Translation: AHH82128.1.
KF691195 Genomic DNA. Translation: AHH82130.1.
KF691196 Genomic DNA. Translation: AHH82131.1.
KF691197 Genomic DNA. Translation: AHH82132.1.
KF691198 Genomic DNA. Translation: AHH82133.1.
KF691205 Genomic DNA. Translation: AHH82140.1.
KF691206 Genomic DNA. Translation: AHH82141.1.
KF691207 Genomic DNA. Translation: AHH82142.1.
KF691219 Genomic DNA. Translation: AHH82154.1.
KF691220 Genomic DNA. Translation: AHH82155.1.
KF691221 Genomic DNA. Translation: AHH82156.1.
KF691222 Genomic DNA. Translation: AHH82157.1.
KF691223 Genomic DNA. Translation: AHH82158.1.
KF691227 Genomic DNA. Translation: AHH82162.1.
KF691228 Genomic DNA. Translation: AHH82163.1.
KF691229 Genomic DNA. Translation: AHH82164.1.
KF691230 Genomic DNA. Translation: AHH82165.1.
KF691231 Genomic DNA. Translation: AHH82166.1.
KF691232 Genomic DNA. Translation: AHH82167.1.
KF691237 Genomic DNA. Translation: AHH82172.1.
KF691239 Genomic DNA. Translation: AHH82174.1.
KF691240 Genomic DNA. Translation: AHH82175.1.
KF691241 Genomic DNA. Translation: AHH82176.1.
KF691242 Genomic DNA. Translation: AHH82177.1.
KF691243 Genomic DNA. Translation: AHH82178.1.
KF691244 Genomic DNA. Translation: AHH82179.1.
KF691250 Genomic DNA. Translation: AHH82185.1.
KF691251 Genomic DNA. Translation: AHH82186.1.
KF691252 Genomic DNA. Translation: AHH82187.1.
KF691253 Genomic DNA. Translation: AHH82188.1.
KF691254 Genomic DNA. Translation: AHH82189.1.
KF691255 Genomic DNA. Translation: AHH82190.1.
KF691256 Genomic DNA. Translation: AHH82191.1.
KF691258 Genomic DNA. Translation: AHH82193.1.
KF691259 Genomic DNA. Translation: AHH82194.1.
KF691260 Genomic DNA. Translation: AHH82195.1.
KF691261 Genomic DNA. Translation: AHH82196.1.
KF691262 Genomic DNA. Translation: AHH82197.1.
KF691263 Genomic DNA. Translation: AHH82198.1.
KF691264 Genomic DNA. Translation: AHH82199.1.
KF691266 Genomic DNA. Translation: AHH82201.1.
KF691267 Genomic DNA. Translation: AHH82202.1.
KF691278 Genomic DNA. Translation: AHH82213.1.
KF691279 Genomic DNA. Translation: AHH82214.1.
KF691280 Genomic DNA. Translation: AHH82215.1.
KF691281 Genomic DNA. Translation: AHH82216.1.
KF691282 Genomic DNA. Translation: AHH82217.1.
KF691283 Genomic DNA. Translation: AHH82218.1.
KF691284 Genomic DNA. Translation: AHH82219.1.
KF691285 Genomic DNA. Translation: AHH82220.1.
KF691286 Genomic DNA. Translation: AHH82221.1.
KF691291 Genomic DNA. Translation: AHH82226.1.
KF691292 Genomic DNA. Translation: AHH82227.1.
KF691293 Genomic DNA. Translation: AHH82228.1.
KF691294 Genomic DNA. Translation: AHH82229.1.
KF691295 Genomic DNA. Translation: AHH82230.1.
KF691296 Genomic DNA. Translation: AHH82231.1.
KF691297 Genomic DNA. Translation: AHH82232.1.
KF691303 Genomic DNA. Translation: AHH82238.1.
KF691304 Genomic DNA. Translation: AHH82239.1.
KF691305 Genomic DNA. Translation: AHH82240.1.
KF691306 Genomic DNA. Translation: AHH82241.1.
KF691307 Genomic DNA. Translation: AHH82242.1.
KF691308 Genomic DNA. Translation: AHH82243.1.
KF691309 Genomic DNA. Translation: AHH82244.1.
KF691310 Genomic DNA. Translation: AHH82245.1.
KF691311 Genomic DNA. Translation: AHH82246.1.
KF691312 Genomic DNA. Translation: AHH82247.1.
KF691313 Genomic DNA. Translation: AHH82248.1.
KF691314 Genomic DNA. Translation: AHH82249.1.
KF691315 Genomic DNA. Translation: AHH82250.1.
KF691324 Genomic DNA. Translation: AHH82259.1.
KF691325 Genomic DNA. Translation: AHH82260.1.
KF691326 Genomic DNA. Translation: AHH82261.1.
KF691327 Genomic DNA. Translation: AHH82262.1.
KF691328 Genomic DNA. Translation: AHH82263.1.
KF691329 Genomic DNA. Translation: AHH82264.1.
KF691330 Genomic DNA. Translation: AHH82265.1.
KF691331 Genomic DNA. Translation: AHH82266.1.
KF691332 Genomic DNA. Translation: AHH82267.1.
KF691347 Genomic DNA. Translation: AHH82282.1.
KF691349 Genomic DNA. Translation: AHH82284.1.
KF691351 Genomic DNA. Translation: AHH82286.1.
KF691352 Genomic DNA. Translation: AHH82287.1.
KF691353 Genomic DNA. Translation: AHH82288.1.
KF691354 Genomic DNA. Translation: AHH82289.1.
KF691355 Genomic DNA. Translation: AHH82290.1.
KF691356 Genomic DNA. Translation: AHH82291.1.
KF691362 Genomic DNA. Translation: AHH82297.1.
KF691363 Genomic DNA. Translation: AHH82298.1.
KF691364 Genomic DNA. Translation: AHH82299.1.
KF691365 Genomic DNA. Translation: AHH82300.1.
KF691366 Genomic DNA. Translation: AHH82301.1.
KF691376 Genomic DNA. Translation: AHH82311.1.
KF691377 Genomic DNA. Translation: AHH82312.1.
KF691378 Genomic DNA. Translation: AHH82313.1.
KF691379 Genomic DNA. Translation: AHH82314.1.
KF691380 Genomic DNA. Translation: AHH82315.1.
KF691381 Genomic DNA. Translation: AHH82316.1.
KF691382 Genomic DNA. Translation: AHH82317.1.
KF691383 Genomic DNA. Translation: AHH82318.1.
KF691439 Genomic DNA. Translation: AHH82374.1.
KF691440 Genomic DNA. Translation: AHH82375.1.
KF691441 Genomic DNA. Translation: AHH82376.1.
KF691446 Genomic DNA. Translation: AHH82381.1.
KF691503 Genomic DNA. Translation: AHH82438.1.
KF691504 Genomic DNA. Translation: AHH82439.1.
KF691505 Genomic DNA. Translation: AHH82440.1.
KF691506 Genomic DNA. Translation: AHH82441.1.
KF691507 Genomic DNA. Translation: AHH82442.1.
KF691508 Genomic DNA. Translation: AHH82443.1.
KF691556 Genomic DNA. Translation: AHH82491.1.
KF691557 Genomic DNA. Translation: AHH82492.1.
KF691558 Genomic DNA. Translation: AHH82493.1.
KF691559 Genomic DNA. Translation: AHH82494.1.
KF691560 Genomic DNA. Translation: AHH82495.1.
KF691561 Genomic DNA. Translation: AHH82496.1.
KF691562 Genomic DNA. Translation: AHH82497.1.
KF691563 Genomic DNA. Translation: AHH82498.1.
KF691564 Genomic DNA. Translation: AHH82499.1.
KF691565 Genomic DNA. Translation: AHH82500.1.
KF691566 Genomic DNA. Translation: AHH82501.1.
KF691567 Genomic DNA. Translation: AHH82502.1.
KF691568 Genomic DNA. Translation: AHH82503.1.

Similar proteinsi

Entry informationi

Entry nameiA0A075D7P7_ARTSF
AccessioniPrimary (citable) accession number: A0A075D7P7
Entry historyiIntegrated into UniProtKB/TrEMBL: October 29, 2014
Last sequence update: October 29, 2014
Last modified: October 25, 2017
This is version 13 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)