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Protein
Submitted name:

Glutamate-gated chloride channel b2

Gene
N/A
Organism
Anopheles gambiae (African malaria mosquito)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionIon channelSAAS annotation
Biological processIon transport, Transport

Names & Taxonomyi

Protein namesi
Submitted name:
Glutamate-gated chloride channel b2Imported
OrganismiAnopheles gambiae (African malaria mosquito)Imported
Taxonomic identifieri7165 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraNematoceraCulicoideaCulicidaeAnophelinaeAnopheles

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei6 – 25HelicalSequence analysisAdd BLAST20
Transmembranei244 – 268HelicalSequence analysisAdd BLAST25
Transmembranei309 – 332HelicalSequence analysisAdd BLAST24
Transmembranei437 – 456HelicalSequence analysisAdd BLAST20

Keywords - Cellular componenti

Cell membraneSAAS annotation, Membrane

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini34 – 243Neur_chan_LBDInterPro annotationAdd BLAST210
Domaini251 – 350Neur_chan_membInterPro annotationAdd BLAST100

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili334 – 354Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the ligand-gated ion channel (TC 1.A.9) family. [View classification]SAAS annotation

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Family and domain databases

Gene3Di2.70.170.10. 1 hit.
InterProiView protein in InterPro
IPR006028. GABAA/Glycine_rcpt.
IPR006202. Neur_chan_lig-bd.
IPR036734. Neur_chan_lig-bd_sf.
IPR006201. Neur_channel.
IPR036719. Neuro-gated_channel_TM_sf.
IPR006029. Neurotrans-gated_channel_TM.
PANTHERiPTHR18945. PTHR18945. 1 hit.
PfamiView protein in Pfam
PF02931. Neur_chan_LBD. 1 hit.
PF02932. Neur_chan_memb. 1 hit.
PRINTSiPR00253. GABAARECEPTR.
PR00252. NRIONCHANNEL.
SUPFAMiSSF63712. SSF63712. 1 hit.
SSF90112. SSF90112. 1 hit.
TIGRFAMsiTIGR00860. LIC. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A075BY48-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASGHFFWAI FYFACLCSAS LANNAKVNFR EKEKKILDQI LGAGKYDARI
60 70 80 90 100
RPSGTNGTDG PAIVRINLFV RSIMTISDIK MEYSVQLTFR EQWLDERLKF
110 120 130 140 150
DDIGGRLKYL TLTEANRVWM PDLFFSNEKE GHFHNIIMPN VYIRIFPYGS
160 170 180 190 200
VLYSIRVSPT LACPTNLKLY PLDRQVCSLR MASYGWTTAD LVFLWKEGDP
210 220 230 240 250
VQVVKNLHLP RFTLEKFLTD YCNSKTNTGE YSCLKVDLLF KREFSYYLIQ
260 270 280 290 300
IYIPCCMLVI VSWVSFWLDQ GAVPARVSLG VTTLLTMATQ TSGINASLPP
310 320 330 340 350
VSYTKAIDVW TGVCLTFVFG ALLEFALVNY ASRSDMHREN MKKKRREMEQ
360 370 380 390 400
ASLDAASDLL DTDSNATFAM KPLVRHPGDP LALEKLRQCE VHMQAPKRPN
410 420 430 440 450
CCRSWLSKFP TSPFKKVPCL GRGQCSRSKR IDVISRITFP LVFALFNLVY
460
WSTYLFREEE ED
Length:462
Mass (Da):52,975
Last modified:October 29, 2014 - v1
Checksum:i5A4539866E94C49D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KC902520 mRNA. Translation: AGS43091.1.

Similar proteinsi

Entry informationi

Entry nameiA0A075BY48_ANOGA
AccessioniPrimary (citable) accession number: A0A075BY48
Entry historyiIntegrated into UniProtKB/TrEMBL: October 29, 2014
Last sequence update: October 29, 2014
Last modified: February 28, 2018
This is version 18 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)