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Protein
Submitted name:

Uncharacterized protein

Gene

T265_10293

Organism
Opisthorchis viverrini
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.SAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandGTP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
ORF Names:T265_10293Imported
OrganismiOpisthorchis viverriniImported
Taxonomic identifieri6198 [NCBI]
Taxonomic lineageiEukaryotaMetazoaPlatyhelminthesTrematodaDigeneaOpisthorchiidaOpisthorchiataOpisthorchiidaeOpisthorchis
Proteomesi
  • UP000054324 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, CytoskeletonSAAS annotation, MicrotubuleSAAS annotation

Interactioni

Subunit structurei

Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.SAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini177 – 374TubulinInterPro annotationAdd BLAST198
Domaini376 – 521Tubulin_CInterPro annotationAdd BLAST146

Sequence similaritiesi

Belongs to the tubulin family.SAAS annotation

Phylogenomic databases

KOiK07374

Family and domain databases

Gene3Di1.10.287.600, 1 hit
3.30.1330.20, 1 hit
3.40.50.1440, 1 hit
InterProiView protein in InterPro
IPR002452 Alpha_tubulin
IPR008280 Tub_FtsZ_C
IPR000217 Tubulin
IPR018316 Tubulin/FtsZ_2-layer-sand-dom
IPR037103 Tubulin/FtsZ_C_sf
IPR036525 Tubulin/FtsZ_GTPase_sf
IPR023123 Tubulin_C
IPR017975 Tubulin_CS
IPR003008 Tubulin_FtsZ_GTPase
PANTHERiPTHR11588 PTHR11588, 1 hit
PfamiView protein in Pfam
PF00091 Tubulin, 1 hit
PF03953 Tubulin_C, 1 hit
PRINTSiPR01162 ALPHATUBULIN
PR01161 TUBULIN
SMARTiView protein in SMART
SM00864 Tubulin, 1 hit
SM00865 Tubulin_C, 1 hit
SUPFAMiSSF52490 SSF52490, 1 hit
SSF55307 SSF55307, 1 hit
PROSITEiView protein in PROSITE
PS00227 TUBULIN, 1 hit

Sequencei

Sequence statusi: Complete.

A0A074Z712-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSVIVVDGFY NQVTTRNYNS DTLSLSCIMI DLNVSLPLSS GANEKDSVYL
60 70 80 90 100
CACALVALPR GLWCCRRAGL RQTPASGLSS NGERFYERNI TINSKRGAHW
110 120 130 140 150
LTMGDAMVVV SWFAAGSASY HFVADYNWGV PSASPSDMDL HIGQAGLQLG
160 170 180 190 200
NACWELFCLE HGVRPDGRPK TKSHEDLGVF FHEAHKGKFV PRAVYVDLEP
210 220 230 240 250
TVGDEVRNGT YRQLFHPEQI ITGKEDAANN YARGYYTVGR EMCDLVLDRI
260 270 280 290 300
RKSADLCDSL QGFFFYNALG GGTGSGLTAL LIERLVIDYA KKAKLQFLIY
310 320 330 340 350
PSPLVSSAVV EPYNSLMTTH TTLEHTDCSF LVDNEAIYYM CQANLELMKP
360 370 380 390 400
GFPNLNRLIG QVVSSITASM RFPGSLNVNL QEFQTNLVPY PRIHFPLSSY
410 420 430 440 450
APLLPASQQF NREISAPRLL VRCFRPQSLM VTCNPRHGKY MACCVLFRGN
460 470 480 490 500
VSGQEVQDAI RHVKKQRTIK FVDWCPTGFK IGVNTQPPTT VPGGDLAKVN
510 520 530 540 550
RSVCMISNST AIAEAWTRLN HKFGLMYAKR SFVHWYVGEG MEENEFTETK
560 570
ENLTALEKDY EEVGMETNLN
Length:570
Mass (Da):63,619
Last modified:October 1, 2014 - v1
Checksum:i9F6CAB3B500AA7BB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KL596972 Genomic DNA Translation: KER21362.1
RefSeqiXP_009174883.1, XM_009176619.1

Genome annotation databases

GeneIDi20324461
KEGGiovi:T265_10293

Similar proteinsi

Entry informationi

Entry nameiA0A074Z712_9TREM
AccessioniPrimary (citable) accession number: A0A074Z712
Entry historyiIntegrated into UniProtKB/TrEMBL: October 1, 2014
Last sequence update: October 1, 2014
Last modified: February 28, 2018
This is version 25 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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