Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Probable glycine dehydrogenase (decarboxylating) subunit 1

Gene

gcvPA

Organism
Geobacillus sp. CAMR5420
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO2 is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.UniRule annotationSAAS annotation

Catalytic activityi

Glycine + [glycine-cleavage complex H protein]-N6-lipoyl-L-lysine = [glycine-cleavage complex H protein]-S-aminomethyl-N6-dihydrolipoyl-L-lysine + CO2.UniRule annotationSAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotationSAAS annotationImported

Names & Taxonomyi

Protein namesi
Recommended name:
Probable glycine dehydrogenase (decarboxylating) subunit 1UniRule annotationSAAS annotation (EC:1.4.4.2UniRule annotationSAAS annotation)
Alternative name(s):
Glycine cleavage system P-protein subunit 1UniRule annotation
Glycine decarboxylase subunit 1UniRule annotation
Glycine dehydrogenase (aminomethyl-transferring) subunit 1UniRule annotation
Gene namesi
Name:gcvPAUniRule annotation
ORF Names:DI44_12225Imported
OrganismiGeobacillus sp. CAMR5420Imported
Taxonomic identifieri1482739 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeGeobacillus
Proteomesi
  • UP000027227 Componenti: Unassembled WGS sequence

Interactioni

Subunit structurei

The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.UniRule annotationSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliA0A063YM50.
SMRiA0A063YM50.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GcvP family. N-terminal subunit subfamily.UniRule annotationSAAS annotation

Family and domain databases

CDDicd00613. GDC-P. 1 hit.
Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 2 hits.
HAMAPiMF_00712. GcvPA. 1 hit.
InterProiView protein in InterPro
IPR023010. GcvPA.
IPR020581. GDC_P.
IPR015424. PyrdxlP-dep_Trfase.
IPR015422. PyrdxlP-dep_Trfase_dom1.
IPR015421. PyrdxlP-dep_Trfase_major.
PfamiView protein in Pfam
PF02347. GDC-P. 1 hit.
PIRSFiPIRSF006815. GcvPA. 1 hit.
SUPFAMiSSF53383. SSF53383. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A063YM50-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLHRYLPMTE EDKQEMLKTI GVASIDDLFA DIPEQVRFRG ELKVKPAKSE
60 70 80 90 100
PELWKELAAL AEKNASVKQY VSFLGAGVYD HYIPAVVDHV LSRSEFYTAY
110 120 130 140 150
TPYQPEISQG ELQAIFEFQT MVCELTGMDV ANSSMYDGGT ALAEAVLLSA
160 170 180 190 200
AHTKRKKVLI STAVHPQYRE VVRTYAKGQK LEVKEIPYDG GITDLKALEA
210 220 230 240 250
EMGDDVACVV VQYPNFFGQI EPLKAIAPLA HEKKSLFVVA SNPLALGVLT
260 270 280 290 300
PPGAFGADIV VGDMQPFGIP TQFGGPHCGY FAVKAPLMRK IPGRLVGQTT
310 320 330 340 350
DEDGRRGFVL TLQAREQHIR RDKATSNICS NQALNALAAS VALSALGKRG
360 370 380 390 400
VKEMAAMNIQ KAHYAKVELE KRGLSSPFAG PFFNEFVIRL GRPVSDVNDR
410 420 430 440
LLEKGIIGGY DLGADYPELA GHMLVAVTEL RTKEEIDRFV NELGDGHA
Length:448
Mass (Da):49,099
Last modified:September 3, 2014 - v1
Checksum:i3D24D4C13A99B2FF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JHUS01000052 Genomic DNA. Translation: KDE47623.1.
RefSeqiWP_011231906.1. NZ_JHUS01000052.1.

Genome annotation databases

EnsemblBacteriaiKDE47623; KDE47623; DI44_12225.
GeneIDi32064310.
PATRICifig|235909.7.peg.2597.

Similar proteinsi

Entry informationi

Entry nameiA0A063YM50_9BACI
AccessioniPrimary (citable) accession number: A0A063YM50
Entry historyiIntegrated into UniProtKB/TrEMBL: September 3, 2014
Last sequence update: September 3, 2014
Last modified: February 28, 2018
This is version 26 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteomeImported