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Protein

Protein RecA

Gene

recA

Organism
Mycobacterium tuberculosis
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi67 – 74ATPUniRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingUniRule annotationSAAS annotation, HydrolaseImported
Biological processDNA damage, DNA recombinationUniRule annotationSAAS annotation, DNA repairUniRule annotation, SOS responseUniRule annotation
LigandATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Protein RecAUniRule annotation
Alternative name(s):
Recombinase AUniRule annotation
Gene namesi
Name:recAUniRule annotationImported
Synonyms:recA_1Imported
ORF Names:C0082_15005Imported, C0083_14995Imported, C0084_15015Imported, C0085_15005Imported, C0086_15005Imported, C0087_14990Imported, C0089_15000Imported, C0090_15000Imported, C0091_15010Imported, C0092_15000Imported, C0093_15000Imported, C0094_15000Imported, C0095_15025Imported, C0096_15005Imported, C0097_15005Imported, CRX58_05510Imported, ERS007663_00628Imported, ERS007665_01758Imported, ERS007670_02085Imported, ERS007672_01842Imported, ERS007679_03054Imported, ERS007681_02594Imported, ERS007703_03431Imported, ERS007720_02931Imported, ERS007722_03836Imported, ERS007741_02827Imported, ERS023446_04054Imported, ERS024213_00782Imported, ERS024276_00304Imported, ERS027653_01289Imported, ERS027654_01999Imported, ERS027656_00675Imported, ERS027659_00493Imported, ERS027666_00506Imported, ERS031537_01341Imported, ERS124361_02183Imported, SAMEA2682864_02041Imported, SAMEA2683035_01664Imported
OrganismiMycobacterium tuberculosisImported
Taxonomic identifieri1773 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
Proteomesi
  • UP000235532 Componenti: Chromosome
  • UP000222967 Componenti: Unassembled WGS sequence
  • UP000235605 Componenti: Chromosome
  • UP000049861 Componenti: Unassembled WGS sequence
  • UP000046932 Componenti: Unassembled WGS sequence
  • UP000041288 Componenti: Unassembled WGS sequence
  • UP000049989 Componenti: Unassembled WGS sequence
  • UP000235433 Componenti: Chromosome
  • UP000048289 Componenti: Unassembled WGS sequence
  • UP000235539 Componenti: Chromosome
  • UP000235486 Componenti: Chromosome
  • UP000049139 Componenti: Unassembled WGS sequence
  • UP000050143 Componenti: Unassembled WGS sequence
  • UP000050164 Componenti: Unassembled WGS sequence
  • UP000049498 Componenti: Unassembled WGS sequence
  • UP000047075 Componenti: Unassembled WGS sequence
  • UP000045842 Componenti: Unassembled WGS sequence
  • UP000235544 Componenti: Chromosome
  • UP000235517 Componenti: Chromosome
  • UP000043293 Componenti: Unassembled WGS sequence
  • UP000048600 Componenti: Unassembled WGS sequence
  • UP000235825 Componenti: Chromosome
  • UP000183655 Componenti: Unassembled WGS sequence
  • UP000039953 Componenti: Unassembled WGS sequence
  • UP000235664 Componenti: Chromosome
  • UP000182946 Componenti: Unassembled WGS sequence
  • UP000235436 Componenti: Chromosome
  • UP000049258 Componenti: Unassembled WGS sequence
  • UP000038802 Componenti: Unassembled WGS sequence
  • UP000235535 Componenti: Chromosome
  • UP000046213 Componenti: Unassembled WGS sequence
  • UP000049114 Componenti: Unassembled WGS sequence
  • UP000235424 Componenti: Chromosome
  • UP000235431 Componenti: Chromosome
  • UP000235832 Componenti: Chromosome
  • UP000045274 Componenti: Unassembled WGS sequence
  • UP000235600 Componenti: Chromosome
  • UP000044938 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini37 – 196RECA_2InterPro annotationAdd BLAST160
Domaini201 – 262RECA_3InterPro annotationAdd BLAST62
Domaini366 – 508DOD-type homing endonucleaseInterPro annotationAdd BLAST143
Domaini664 – 714RECA_3InterPro annotationAdd BLAST51
Domaini670 – 692INTEIN_C_TERInterPro annotationAdd BLAST23

Sequence similaritiesi

Belongs to the RecA family.UniRule annotationSAAS annotation

Family and domain databases

CDDicd00983. recA. 1 hit.
Gene3Di3.10.28.10. 1 hit.
3.30.250.10. 1 hit.
HAMAPiMF_00268. RecA. 1 hit.
InterProiView protein in InterPro
IPR003593. AAA+_ATPase.
IPR013765. DNA_recomb/repair_RecA.
IPR020584. DNA_recomb/repair_RecA_CS.
IPR003586. Hint_dom_C.
IPR003587. Hint_dom_N.
IPR036844. Hint_dom_sf.
IPR027434. Homing_endonucl.
IPR006142. INTEIN.
IPR030934. Intein_C.
IPR004042. Intein_endonuc.
IPR006141. Intein_N.
IPR004860. LAGLIDADG_2.
IPR027417. P-loop_NTPase.
IPR020588. RecA_ATP-bd.
IPR023400. RecA_C.
IPR020587. RecA_monomer-monomer_interface.
PANTHERiPTHR22942:SF1. PTHR22942:SF1. 1 hit.
PfamiView protein in Pfam
PF14528. LAGLIDADG_3. 1 hit.
PF00154. RecA. 1 hit.
PRINTSiPR00379. INTEIN.
PR00142. RECA.
SMARTiView protein in SMART
SM00382. AAA. 1 hit.
SM00305. HintC. 1 hit.
SM00306. HintN. 1 hit.
SUPFAMiSSF51294. SSF51294. 2 hits.
SSF52540. SSF52540. 1 hit.
SSF54752. SSF54752. 1 hit.
SSF55608. SSF55608. 1 hit.
TIGRFAMsiTIGR01443. intein_Cterm. 1 hit.
TIGR01445. intein_Nterm. 1 hit.
TIGR02012. tigrfam_recA. 1 hit.
PROSITEiView protein in PROSITE
PS50818. INTEIN_C_TER. 1 hit.
PS50819. INTEIN_ENDONUCLEASE. 1 hit.
PS50817. INTEIN_N_TER. 1 hit.
PS00321. RECA_1. 1 hit.
PS50162. RECA_2. 1 hit.
PS50163. RECA_3. 2 hits.

Sequencei

Sequence statusi: Complete.

A0A045GV14-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTQTPDREKA LELAVAQIEK SYGKGSVMRL GDEARQPISV IPTGSIALDV
60 70 80 90 100
ALGIGGLPRG RVIEIYGPES SGKTTVALHA VANAQAAGGV AAFIDAEHAL
110 120 130 140 150
DPDYAKKLGV DTDSLLVSQP DTGEQALEIA DMLIRSGALD IVVIDSVAAL
160 170 180 190 200
VPRAELEGEM GDSHVGLQAR LMSQALRKMT GALNNSGTTA IFINQLRDKI
210 220 230 240 250
GVMFGSPETT TGGKALKFYA SVRMDVRRVE TLKDGTNAVG NRTRVKVVKN
260 270 280 290 300
KCLAEGTRIF DPVTGTTHRI EDVVDGRKPI HVVAAAKDGT LHARPVVSWF
310 320 330 340 350
DQGTRDVIGL RIAGGAIVWA TPDHKVLTEY GWRAAGELRK GDRVAQPRRF
360 370 380 390 400
DGFGDSAPIP ADHARLLGYL IGDGRDGWVG GKTPINFINV QRALIDDVTR
410 420 430 440 450
IAATLGCAAH PQGRISLAIA HRPGERNGVA DLCQQAGIYG KLAWEKTIPN
460 470 480 490 500
WFFEPDIAAD IVGNLLFGLF ESDGWVSREQ TGALRVGYTT TSEQLAHQIH
510 520 530 540 550
WLLLRFGVGS TVRDYDPTQK RPSIVNGRRI QSKRQVFEVR ISGMDNVTAF
560 570 580 590 600
AESVPMWGPR GAALIQAIPE ATQGRRRGSQ ATYLAAEMTD AVLNYLDERG
610 620 630 640 650
VTAQEAAAMI GVASGDPRGG MKQVLGASRL RRDRVQALAD ALDDKFLHDM
660 670 680 690 700
LAEELRYSVI REVLPTRRAR TFDLEVEELH TLVAEGVVVH NCSPPFKQAE
710 720 730 740 750
FDILYGKGIS REGSLIDMGV DQGLIRKSGA WFTYEGEQLG QGKENARNFL
760 770 780 790
VENADVADEI EKKIKEKLGI GAVVTDDPSN DGVLPAPVDF
Length:790
Mass (Da):85,389
Last modified:July 9, 2014 - v1
Checksum:iAD16340D2ED5E572
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP025593 Genomic DNA. Translation: AUP52333.1.
CP025594 Genomic DNA. Translation: AUP56471.1.
CP025595 Genomic DNA. Translation: AUP60611.1.
CP025596 Genomic DNA. Translation: AUP64737.1.
CP025597 Genomic DNA. Translation: AUP68880.1.
CP025598 Genomic DNA. Translation: AUP73021.1.
CP025599 Genomic DNA. Translation: AUP84302.1.
CP025601 Genomic DNA. Translation: AUP92568.1.
CP025602 Genomic DNA. Translation: AUP96699.1.
CP025603 Genomic DNA. Translation: AUQ00829.1.
CP025604 Genomic DNA. Translation: AUQ04980.1.
CP025605 Genomic DNA. Translation: AUQ09108.1.
CP025606 Genomic DNA. Translation: AUQ13238.1.
CP025607 Genomic DNA. Translation: AUQ17374.1.
CP025608 Genomic DNA. Translation: AUQ21496.1.
CFOE01000357 Genomic DNA. Translation: CFE40660.1.
CNCN01000038 Genomic DNA. Translation: CKN73931.1.
CNDE01000130 Genomic DNA. Translation: CKO64452.1.
CNFT01000066 Genomic DNA. Translation: CKQ98158.1.
CNFV01000068 Genomic DNA. Translation: CKR14284.1.
CNFS01000235 Genomic DNA. Translation: CKR42670.1.
CNFR01000369 Genomic DNA. Translation: CKR67893.1.
CNGG01000062 Genomic DNA. Translation: CKS08769.1.
CNIS01000170 Genomic DNA. Translation: CKU82934.1.
CHDS01000037 Genomic DNA. Translation: CNG88014.1.
CQGE01000188 Genomic DNA. Translation: CNN60126.1.
CQPV01000061 Genomic DNA. Translation: CNU16153.1.
CQPL01000403 Genomic DNA. Translation: CNU82724.1.
CQPW01000313 Genomic DNA. Translation: CNU86544.1.
CHEE01000295 Genomic DNA. Translation: COV44581.1.
CSAD01000497 Genomic DNA. Translation: COW07300.1.
CSAE01000465 Genomic DNA. Translation: COW33922.1.
CSAJ01000422 Genomic DNA. Translation: COW60901.1.
CHKL01000362 Genomic DNA. Translation: COW62573.1.
CSAM01000446 Genomic DNA. Translation: COW96845.1.
PDLG01000001 Genomic DNA. Translation: PHG95607.1.
FPTZ01000009 Genomic DNA. Translation: SGH64617.1.
FPXX01000011 Genomic DNA. Translation: SGM24437.1.
RefSeqiWP_003414006.1. NZ_PDLG01000001.1.

Genome annotation databases

EnsemblBacteriaiAMC47189; AMC47189; RN05_2913.
CFE40660; CFE40660; ERS007681_02594.
CKN73931; CKN73931; ERS024276_00304.
CKO64452; CKO64452; ERS024213_00782.
CKQ98158; CKQ98158; ERS027659_00493.
CKR14284; CKR14284; ERS027656_00675.
CKR42670; CKR42670; ERS027653_01289.
CKR67893; CKR67893; ERS027654_01999.
CKS08769; CKS08769; ERS027666_00506.
CKU82934; CKU82934; ERS031537_01341.
CNG88014; CNG88014; ERS124361_02183.
CNN60126; CNN60126; ERS023446_04054.
CNU16153; CNU16153; ERS007663_00628.
CNU82724; CNU82724; ERS007670_02085.
CNU86544; CNU86544; ERS007665_01758.
CNZ22247; CNZ22247; ERS013471_03848.
COV44581; COV44581; ERS007672_01842.
COW07300; COW07300; ERS007679_03054.
COW33922; COW33922; ERS007703_03431.
COW60901; COW60901; ERS007720_02931.
COW62573; COW62573; ERS007741_02827.
COW96845; COW96845; ERS007722_03836.
PATRICifig|1773.206.peg.2251.

Similar proteinsi

Entry informationi

Entry nameiA0A045GV14_MYCTX
AccessioniPrimary (citable) accession number: A0A045GV14
Entry historyiIntegrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: March 28, 2018
This is version 43 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported