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Protein
Submitted name:

BCR downstream signaling 1, isoform CRA_a

Gene

BRDG1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
BCR downstream signaling 1, isoform CRA_aImported
Gene namesi
Name:BRDG1Imported
ORF Names:hCG_40344Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000035720.7.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PaxDbiA0A024RD91.
PRIDEiA0A024RD91.

Expressioni

Gene expression databases

BgeeiENSG00000035720.
ExpressionAtlasiA0A024RD91. baseline and differential.

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliA0A024RD91.
SMRiA0A024RD91.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini25 – 121PHInterPro annotationAdd BLAST97
Domaini182 – 280SH2InterPro annotationAdd BLAST99

Keywords - Domaini

SH2 domainPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG410IGPX. Eukaryota.
ENOG4111PK4. LUCA.
OMAiYWTELRG.
OrthoDBiEOG091G0929.
PhylomeDBiA0A024RD91.

Family and domain databases

CDDicd10403. SH2_STAP1. 1 hit.
Gene3Di2.30.29.30. 1 hit.
3.30.505.10. 1 hit.
InterProiView protein in InterPro
IPR011993. PH_dom-like.
IPR001849. PH_domain.
IPR000980. SH2.
IPR036860. SH2_dom_sf.
IPR035877. STAP1_SH2.
PfamiView protein in Pfam
PF00169. PH. 1 hit.
PF00017. SH2. 1 hit.
SMARTiView protein in SMART
SM00233. PH. 1 hit.
SM00252. SH2. 1 hit.
SUPFAMiSSF50729. SSF50729. 1 hit.
SSF55550. SSF55550. 1 hit.
PROSITEiView protein in PROSITE
PS50003. PH_DOMAIN. 1 hit.
PS50001. SH2. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A024RD91-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMAKKPPKPA PRRIFQERLK ITALPLYFEG FLLIKRSGYR EYEHYWTELR
60 70 80 90 100
GTTLFFYTDK KSIIYVDKLD IVDLTCLTEQ NSTEKNCAKF TLVLPKEEVQ
110 120 130 140 150
LKTENTESGE EWRGFILTVT ELSVPQNVSL LPGQVIKLHE VLEREKKRRI
160 170 180 190 200
ETEQSTSVEK EKEPTEDYVD VLNPMPACFY TVSRKEATEM LQKNPSLGNM
210 220 230 240 250
ILRPGSDSRN YSITIRQEID IPRIKHYKVM SVGQNYTIEL EKPVTLPNLF
260 270 280 290
SVIDYFVKET RGNLRPFICS TDENTGQEPS MEGRSEKLKK NPHIA
Length:295
Mass (Da):34,291
Last modified:July 9, 2014 - v1
Checksum:i8C242AC5C61038E0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471057 Genomic DNA. Translation: EAX05548.1.
RefSeqiNP_001304698.1. NM_001317769.1.
NP_036240.1. NM_012108.3.
UniGeneiHs.435579.

Genome annotation databases

GeneIDi26228.
KEGGihsa:26228.

Similar proteinsi

Entry informationi

Entry nameiA0A024RD91_HUMAN
AccessioniPrimary (citable) accession number: A0A024RD91
Entry historyiIntegrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: October 25, 2017
This is version 30 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.