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Protein
Submitted name:

Cyclin-dependent kinase inhibitor 1A (P21, Cip1), isoform CRA_a

Gene

CDKN1A

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

KinaseImported, Transferase

Names & Taxonomyi

Protein namesi
Submitted name:
Cyclin-dependent kinase inhibitor 1A (P21, Cip1), isoform CRA_aImported
Gene namesi
Name:CDKN1AImported
ORF Names:hCG_15367Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000244741.

Family & Domainsi

Phylogenomic databases

eggNOGiKOG4743. Eukaryota.
ENOG410XXN5. LUCA.
KOiK06625.
OMAiFAWERVW.
OrthoDBiEOG091G19PZ.
PhylomeDBiA0A024RCX5.

Family and domain databases

InterProiIPR003175. CDI.
IPR029841. CDKN1A_vertebrate.
[Graphical view]
PANTHERiPTHR10265. PTHR10265. 1 hit.
PTHR10265:SF16. PTHR10265:SF16. 1 hit.
PfamiPF02234. CDI. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A0A024RCX5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEPAGDVRQ NPCGSKACRR LFGPVDSEQL SRDCDALMAG CIQEARERWN
60 70 80 90 100
FDFVTETPLE GDFAWERVRG LGLPKLYLPT GPRRGRDELG GGRRPGTSPA
110 120 130 140 150
LLQGTAEEDH VDLSLSCTLV PRSGEQAEGS PGGPGDSQGR KRRQTSMTDF
160
YHSKRRLIFS KRKP
Length:164
Mass (Da):18,119
Last modified:July 9, 2014 - v1
Checksum:i98D1E7C519ADFCA9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471081 Genomic DNA. Translation: EAX03905.1.
CH471081 Genomic DNA. Translation: EAX03907.1.
RefSeqiNP_000380.1. NM_000389.4.
NP_001207706.1. NM_001220777.1.
NP_001207707.1. NM_001220778.1.
NP_510867.1. NM_078467.2.
UniGeneiHs.370771.
Hs.732576.

Genome annotation databases

GeneIDi1026.
KEGGihsa:1026.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471081 Genomic DNA. Translation: EAX03905.1.
CH471081 Genomic DNA. Translation: EAX03907.1.
RefSeqiNP_000380.1. NM_000389.4.
NP_001207706.1. NM_001220777.1.
NP_001207707.1. NM_001220778.1.
NP_510867.1. NM_078467.2.
UniGeneiHs.370771.
Hs.732576.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000244741.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi1026.
KEGGihsa:1026.

Organism-specific databases

CTDi1026.

Phylogenomic databases

eggNOGiKOG4743. Eukaryota.
ENOG410XXN5. LUCA.
KOiK06625.
OMAiFAWERVW.
OrthoDBiEOG091G19PZ.
PhylomeDBiA0A024RCX5.

Miscellaneous databases

GenomeRNAii1026.

Family and domain databases

InterProiIPR003175. CDI.
IPR029841. CDKN1A_vertebrate.
[Graphical view]
PANTHERiPTHR10265. PTHR10265. 1 hit.
PTHR10265:SF16. PTHR10265:SF16. 1 hit.
PfamiPF02234. CDI. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiA0A024RCX5_HUMAN
AccessioniPrimary (citable) accession number: A0A024RCX5
Entry historyi
Integrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: September 7, 2016
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.