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Protein
Submitted name:

Cyclin-dependent kinase inhibitor 1A (P21, Cip1), isoform CRA_a

Gene

CDKN1A

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseImported, Transferase

Names & Taxonomyi

Protein namesi
Submitted name:
Cyclin-dependent kinase inhibitor 1A (P21, Cip1), isoform CRA_aImported
Gene namesi
Name:CDKN1AImported
ORF Names:hCG_15367Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000124762.13.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSG00000124762.
ExpressionAtlasiA0A024RCX5. baseline and differential.

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

SMRiA0A024RCX5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiKOG4743. Eukaryota.
ENOG410XXN5. LUCA.
KOiK06625.
OMAiFAWERVW.
OrthoDBiEOG091G19PZ.

Family and domain databases

InterProiView protein in InterPro
IPR003175. CDI.
IPR029841. CDKN1A_vertebrate.
PANTHERiPTHR10265. PTHR10265. 1 hit.
PTHR10265:SF29. PTHR10265:SF29. 1 hit.
PfamiView protein in Pfam
PF02234. CDI. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A024RCX5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEPAGDVRQ NPCGSKACRR LFGPVDSEQL SRDCDALMAG CIQEARERWN
60 70 80 90 100
FDFVTETPLE GDFAWERVRG LGLPKLYLPT GPRRGRDELG GGRRPGTSPA
110 120 130 140 150
LLQGTAEEDH VDLSLSCTLV PRSGEQAEGS PGGPGDSQGR KRRQTSMTDF
160
YHSKRRLIFS KRKP
Length:164
Mass (Da):18,119
Last modified:July 9, 2014 - v1
Checksum:i98D1E7C519ADFCA9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471081 Genomic DNA. Translation: EAX03905.1.
CH471081 Genomic DNA. Translation: EAX03907.1.
RefSeqiNP_000380.1. NM_000389.4.
NP_001207706.1. NM_001220777.1.
NP_001207707.1. NM_001220778.1.
NP_510867.1. NM_078467.2.
UniGeneiHs.370771.
Hs.732576.

Genome annotation databases

GeneIDi1026.
KEGGihsa:1026.

Similar proteinsi

Entry informationi

Entry nameiA0A024RCX5_HUMAN
AccessioniPrimary (citable) accession number: A0A024RCX5
Entry historyiIntegrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: September 27, 2017
This is version 32 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.