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Protein
Submitted name:

V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b

Gene

KRAS

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandGTP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_bImported
Gene namesi
Name:KRASImported
ORF Names:hCG_14731Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Proteomic databases

PRIDEiA0A024RAV5.

Expressioni

Gene expression databases

BgeeiENSG00000133703.
ExpressionAtlasiA0A024RAV5. baseline and differential.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2MSCNMR-B1-185[»]
2MSDNMR-B1-185[»]
2MSENMR-B1-185[»]
ProteinModelPortaliA0A024RAV5.
SMRiA0A024RAV5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

OMAiQSWAVNM.

Family and domain databases

InterProiView protein in InterPro
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR001806. Small_GTPase.
IPR020849. Small_GTPase_Ras.
PANTHERiPTHR24070. PTHR24070. 1 hit.
PfamiView protein in Pfam
PF00071. Ras. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00231. small_GTP. 1 hit.
PROSITEiView protein in PROSITE
PS51421. RAS. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A024RAV5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTEYKLVVVG AGGVGKSALT IQLIQNHFVD EYDPTIEDSY RKQVVIDGET
60 70 80 90 100
CLLDILDTAG QEEYSAMRDQ YMRTGEGFLC VFAINNTKSF EDIHHYREQI
110 120 130 140 150
KRVKDSEDVP MVLVGNKCDL PSRTVDTKQA QDLARSYGIP FIETSAKTRQ
160 170 180
GVDDAFYTLV REIRKHKEKM SKDGKKKKKK SKTKCVIM
Length:188
Mass (Da):21,425
Last modified:July 9, 2014 - v1
Checksum:iB1B6D189BB259861
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471094 Genomic DNA. Translation: EAW96513.1.
RefSeqiNP_004976.2. NM_004985.4.
XP_011518955.1. XM_011520653.2.
UniGeneiHs.505033.

Genome annotation databases

GeneIDi3845.

Similar proteinsi

Entry informationi

Entry nameiA0A024RAV5_HUMAN
AccessioniPrimary (citable) accession number: A0A024RAV5
Entry historyiIntegrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: August 30, 2017
This is version 28 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources