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Protein
Submitted name:

Bridging integrator 1, isoform CRA_d

Gene

BIN1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Bridging integrator 1, isoform CRA_dImported
Gene namesi
Name:BIN1Imported
ORF Names:hCG_40441Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000136717.14.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSG00000136717.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini29 – 245BARInterPro annotationAdd BLAST217
Domaini381 – 454SH3InterPro annotationAdd BLAST74

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili157 – 191Sequence analysisAdd BLAST35
Coiled coili222 – 242Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis, SH3 domainPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG410ITR4. Eukaryota.
ENOG410XQXT. LUCA.

Family and domain databases

CDDicd12139. SH3_Bin1. 1 hit.
Gene3Di1.20.1270.60. 1 hit.
InterProiView protein in InterPro
IPR027267. AH/BAR_dom_sf.
IPR003005. Amphiphysin.
IPR035471. Amphiphysin-2_SH3.
IPR003017. Amphiphysin_1.
IPR003023. Amphiphysin_2.
IPR004148. BAR_dom.
IPR036028. SH3-like_dom_sf.
IPR001452. SH3_domain.
PANTHERiPTHR44669. PTHR44669. 2 hits.
PfamiView protein in Pfam
PF03114. BAR. 1 hit.
PF14604. SH3_9. 1 hit.
PRINTSiPR01251. AMPHIPHYSIN.
PR01253. AMPHIPHYSIN2.
PR00452. SH3DOMAIN.
SMARTiView protein in SMART
SM00721. BAR. 1 hit.
SM00326. SH3. 1 hit.
SUPFAMiSSF103657. SSF103657. 1 hit.
SSF50044. SSF50044. 1 hit.
PROSITEiView protein in PROSITE
PS51021. BAR. 1 hit.
PS50002. SH3. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A024RAE9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEMGSKGVT AGKIASNVQK KLTRAQEKVL QKLGKADETK DEQFEQCVQN
60 70 80 90 100
FNKQLTEGTR LQKDLRTYLA SVKAMHEASK KLNECLQEVY EPDWPGRDEA
110 120 130 140 150
NKIAENNDLL WMDYHQKLVD QALLTMDTYL GQFPDIKSRI AKRGRKLVDY
160 170 180 190 200
DSARHHYESL QTAKKKDEAK IAKAEEELIK AQKVFEEMNV DLQEELPSLW
210 220 230 240 250
NSRVGFYVNT FQSIAGLEEN FHKEMSKLNQ NLNDVLVGLE KQHGSNTFTV
260 270 280 290 300
KAQPRKKSKL FSRLRRKKNS DNAPAKGNKS PSPPDGSPAA TPEIRVNHEP
310 320 330 340 350
EPAGGATPGA TLPKSPSQPA EASEVAGGTQ PAAGAQEPGE TAASEAASSS
360 370 380 390 400
LPAVVVETFP ATVNGTVEGG SGAGRLDLPP GFMFKVQAQH DYTATDTDEL
410 420 430 440 450
QLKAGDVVLV IPFQNPEEQD EGWLMGVKES DWNQHKELEK CRGVFPENFT

ERVP
Length:454
Mass (Da):50,185
Last modified:July 9, 2014 - v1
Checksum:i7E2ADD14E9D56D9E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471103 Genomic DNA. Translation: EAW95290.1.
CH471103 Genomic DNA. Translation: EAW95293.1.
RefSeqiNP_004296.1. NM_004305.3.
UniGeneiHs.193163.

Genome annotation databases

GeneIDi274.

Similar proteinsi

Entry informationi

Entry nameiA0A024RAE9_HUMAN
AccessioniPrimary (citable) accession number: A0A024RAE9
Entry historyiIntegrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: January 31, 2018
This is version 33 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.