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Protein
Submitted name:

Metadherin, isoform CRA_a

Gene

MTDH

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Metadherin, isoform CRA_aImported
Gene namesi
Name:MTDHImported
ORF Names:hCG_15302Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei50 – 78HelicalSequence analysisAdd BLAST29

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000338235.

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IIV9. Eukaryota.
ENOG410YF4D. LUCA.
OMAiDWGRSWS.
OrthoDBiEOG091G0889.

Family and domain databases

InterProiIPR031402. LYRIC.
[Graphical view]
PfamiPF15686. LYRIC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A0A024R9D2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAARSWQDEL AQQAEEGSAR LREMLSVGLG FLRTELGLDL GLEPKRYPGW
60 70 80 90 100
VILVGTGALG LLLLFLLGYG WAAACAGARK KRRSPPRKRE EAAAVPAAAP
110 120 130 140 150
DDLALLKNLR SEEQKKKNRK KLSEKPKPNG RTVEVAEGEA VRTPQSVTAK
160 170 180 190 200
QPPEIDKKNE KSKKNKKKSK SDAKAVQNSS RHDGKEVDEG AWETKISHRE
210 220 230 240 250
KRQQRKRDKV LTDSGSLDST IPGIENTITV TTEQLTTASF PVGSKKNKGD
260 270 280 290 300
SHLNVQVSNF KSGKGDSTLQ VSSGLNENLT VNGGGWNEKS VKLSSQISAG
310 320 330 340 350
EEKWNSVSPA SAGKRKTEPS AWSQDTGDAN TNGKDWGRSW SDRSIFSGIG
360 370 380 390 400
STAEPVSQST TSDYQWDVSR NQPYIDDEWS GLNGLSSADP NSDWNAPAEE
410 420 430 440 450
WGNWVDEERA SLLKSQEPIP DDQKVSDDDK EKGEGALPTG KSKKKKKKKK
460 470 480 490 500
KQGEDNSTAQ DTEELEKEIR EDLPVNTSKT RPKQEKAFSL KTISTSDPAE
510 520 530 540 550
VLVKNSQPIK TLPPATSTEP SVILSKSDSD KSSSQVPPIL QETDKSKSNT
560 570 580
KQNSVPPSQT KSETSWESPK QIKKKKKARR ET
Length:582
Mass (Da):63,837
Last modified:July 9, 2014 - v1
Checksum:i2460D6218FD3A4C4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471060 Genomic DNA. Translation: EAW91760.1.
CH471060 Genomic DNA. Translation: EAW91761.1.
RefSeqiNP_848927.2. NM_178812.3.
UniGeneiHs.377155.

Genome annotation databases

GeneIDi92140.
KEGGihsa:92140.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471060 Genomic DNA. Translation: EAW91760.1.
CH471060 Genomic DNA. Translation: EAW91761.1.
RefSeqiNP_848927.2. NM_178812.3.
UniGeneiHs.377155.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000338235.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi92140.
KEGGihsa:92140.

Organism-specific databases

CTDi92140.

Phylogenomic databases

eggNOGiENOG410IIV9. Eukaryota.
ENOG410YF4D. LUCA.
OMAiDWGRSWS.
OrthoDBiEOG091G0889.

Miscellaneous databases

GenomeRNAii92140.

Family and domain databases

InterProiIPR031402. LYRIC.
[Graphical view]
PfamiPF15686. LYRIC. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiA0A024R9D2_HUMAN
AccessioniPrimary (citable) accession number: A0A024R9D2
Entry historyi
Integrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: November 2, 2016
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.