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Protein
Submitted name:

HCG40889, isoform CRA_b

Gene

hCG_40889

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Names & Taxonomyi

Protein namesi
Submitted name:
HCG40889, isoform CRA_bImported
Gene namesi
ORF Names:hCG_40889Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 18Sequence analysisAdd BLAST18
ChainiPRO_501001076119 – 1231Sequence analysisAdd BLAST1213

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi114 ↔ 141PROSITE-ProRule annotation
Disulfide bondi178 ↔ 205PROSITE-ProRule annotation
Disulfide bondi630 ↔ 673PROSITE-ProRule annotation
Disulfide bondi989 ↔ 1032PROSITE-ProRule annotation
Disulfide bondi1048 ↔ 1091PROSITE-ProRule annotation
Disulfide bondi1109 ↔ 1152PROSITE-ProRule annotation
Disulfide bondi1201 ↔ 1228PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000356399.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini19 – 82Sushi (CCP/SCR)InterPro annotationAdd BLAST64
Domaini83 – 143Sushi (CCP/SCR)InterPro annotationAdd BLAST61
Domaini144 – 207Sushi (CCP/SCR)InterPro annotationAdd BLAST64
Domaini208 – 264Sushi (CCP/SCR)InterPro annotationAdd BLAST57
Domaini265 – 322Sushi (CCP/SCR)InterPro annotationAdd BLAST58
Domaini387 – 444Sushi (CCP/SCR)InterPro annotationAdd BLAST58
Domaini446 – 507Sushi (CCP/SCR)InterPro annotationAdd BLAST62
Domaini515 – 566Sushi (CCP/SCR)InterPro annotationAdd BLAST52
Domaini567 – 625Sushi (CCP/SCR)InterPro annotationAdd BLAST59
Domaini628 – 686Sushi (CCP/SCR)InterPro annotationAdd BLAST59
Domaini689 – 746Sushi (CCP/SCR)InterPro annotationAdd BLAST58
Domaini751 – 805Sushi (CCP/SCR)InterPro annotationAdd BLAST55
Domaini809 – 866Sushi (CCP/SCR)InterPro annotationAdd BLAST58
Domaini868 – 928Sushi (CCP/SCR)InterPro annotationAdd BLAST61
Domaini929 – 986Sushi (CCP/SCR)InterPro annotationAdd BLAST58
Domaini987 – 1045Sushi (CCP/SCR)InterPro annotationAdd BLAST59
Domaini1046 – 1104Sushi (CCP/SCR)InterPro annotationAdd BLAST59
Domaini1107 – 1165Sushi (CCP/SCR)InterPro annotationAdd BLAST59
Domaini1194 – 1230Sushi (CCP/SCR)InterPro annotationAdd BLAST37

Keywords - Domaini

SignalSequence analysis, SushiPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG410IVQ9. Eukaryota.
ENOG410YBAR. LUCA.
KOiK04004.
OMAiRINFREC.
OrthoDBiEOG091G00V4.

Family and domain databases

CDDicd00033. CCP. 16 hits.
InterProiView protein in InterPro
IPR000436. Sushi_SCR_CCP_dom.
PfamiView protein in Pfam
PF00084. Sushi. 19 hits.
SMARTiView protein in SMART
SM00032. CCP. 20 hits.
SUPFAMiSSF57535. SSF57535. 18 hits.
PROSITEiView protein in PROSITE
PS50923. SUSHI. 19 hits.

Sequencei

Sequence statusi: Complete.

A0A024R962-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRLLAKIICL MLWAICVAED CNELPPRRNT EILTGSWSDQ TYPEGTQAIY
60 70 80 90 100
KCRPGYRSLG NVIMVCRKGE WVALNPLRKC QKRPCGHPGD TPFGTFTLTG
110 120 130 140 150
GNVFEYGVKA VYTCNEGYQL LGEINYRECD TDGWTNDIPI CEVVKCLPVT
160 170 180 190 200
APENGKIVSS AMEPDREYHF GQAVRFVCNS GYKIEGDEEM HCSDDGFWSK
210 220 230 240 250
EKPKCVEISC KSPDVINGSP ISQKIIYKEN ERFQYKCNMG YEYSERGDAV
260 270 280 290 300
CTESGWRPLP SCEEKSCDNP YIPNGDYSPL RIKHRTGDEI TYQCRNGFYP
310 320 330 340 350
ATRGNTAKCT STGWIPAPRC TLKPCDYPDI KHGGLYHENM RRPYFPVAVG
360 370 380 390 400
KYYSYYCDEH FETPSGSYWD HIHCTQDGWS PAVPCLRKCY FPYLENGYNQ
410 420 430 440 450
NHGRKFVQGK SIDVACHPGY ALPKAQTTVT CMENGWSPTP RCIRVKTCSK
460 470 480 490 500
SSIDIENGFI SESQYTYALK EKAKYQCKLG YVTADGETSG SITCGKDGWS
510 520 530 540 550
AQPTCIKSCD IPVFMNARTK NDFTWFKLND TLDYECHDGY ESNTGSTTGS
560 570 580 590 600
IVCGYNGWSD LPICYERECE LPKIDVHLVP DRKKDQYKVG EVLKFSCKPG
610 620 630 640 650
FTIVGPNSVQ CYHFGLSPDL PICKEQVQSC GPPPELLNGN VKEKTKEEYG
660 670 680 690 700
HSEVVEYYCN PRFLMKGPNK IQCVDGEWTT LPVCIVEEST CGDIPELEHG
710 720 730 740 750
WAQLSSPPYY YGDSVEFNCS ESFTMIGHRS ITCIHGVWTQ LPQCVAIDKL
760 770 780 790 800
KKCKSSNLII LEEHLKNKKE FDHNSNIRYR CRGKEGWIHT VCINGRWDPE
810 820 830 840 850
VNCSMAQIQL CPPPPQIPNS HNMTTTLNYR DGEKVSVLCQ ENYLIQEGEE
860 870 880 890 900
ITCKDGRWQS IPLCVEKIPC SQPPQIEHGT INSSRSSQES YAHGTKLSYT
910 920 930 940 950
CEGGFRISEE NETTCYMGKW SSPPQCEGLP CKSPPEISHG VVAHMSDSYQ
960 970 980 990 1000
YGEEVTYKCF EGFGIDGPAI AKCLGEKWSH PPSCIKTDCL SLPSFENAIP
1010 1020 1030 1040 1050
MGEKKDVYKA GEQVTYTCAT YYKMDGASNV TCINSRWTGR PTCRDTSCVN
1060 1070 1080 1090 1100
PPTVQNAYIV SRQMSKYPSG ERVRYQCRSP YEMFGDEEVM CLNGNWTEPP
1110 1120 1130 1140 1150
QCKDSTGKCG PPPPIDNGDI TSFPLSVYAP ASSVEYQCQN LYQLEGNKRI
1160 1170 1180 1190 1200
TCRNGQWSEP PKCLHPCVIS REIMENYNIA LRWTAKQKLY SRTGESVEFV
1210 1220 1230
CKRGYRLSSR SHTLRTTCWD GKLEYPTCAK R
Length:1,231
Mass (Da):139,070
Last modified:July 9, 2014 - v1
Checksum:i2046A9212747B881
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471067 Genomic DNA. Translation: EAW91260.1.
CH471067 Genomic DNA. Translation: EAW91261.1.
RefSeqiNP_000177.2. NM_000186.3.
UniGeneiHs.363396.

Genome annotation databases

GeneIDi3075.
KEGGihsa:3075.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471067 Genomic DNA. Translation: EAW91260.1.
CH471067 Genomic DNA. Translation: EAW91261.1.
RefSeqiNP_000177.2. NM_000186.3.
UniGeneiHs.363396.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000356399.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi3075.
KEGGihsa:3075.

Organism-specific databases

CTDi3075.

Phylogenomic databases

eggNOGiENOG410IVQ9. Eukaryota.
ENOG410YBAR. LUCA.
KOiK04004.
OMAiRINFREC.
OrthoDBiEOG091G00V4.

Miscellaneous databases

GenomeRNAii3075.

Family and domain databases

CDDicd00033. CCP. 16 hits.
InterProiView protein in InterPro
IPR000436. Sushi_SCR_CCP_dom.
PfamiView protein in Pfam
PF00084. Sushi. 19 hits.
SMARTiView protein in SMART
SM00032. CCP. 20 hits.
SUPFAMiSSF57535. SSF57535. 18 hits.
PROSITEiView protein in PROSITE
PS50923. SUSHI. 19 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiA0A024R962_HUMAN
AccessioniPrimary (citable) accession number: A0A024R962
Entry historyiIntegrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: May 10, 2017
This is version 25 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.