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Protein
Submitted name:

Mitogen-activated protein kinase kinase 6, isoform CRA_a

Gene

MAP2K6

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionKinase, Serine/threonine-protein kinaseUniRule annotation, Transferase
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Mitogen-activated protein kinase kinase 6, isoform CRA_aImported
Gene namesi
Name:MAP2K6Imported
ORF Names:hCG_28772Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000108984.13.

Expressioni

Gene expression databases

BgeeiENSG00000108984.

Structurei

3D structure databases

SMRiA0A024R8K3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 258Protein kinaseInterPro annotationAdd BLAST258

Sequence similaritiesi

Belongs to the protein kinase superfamily.UniRule annotation

Phylogenomic databases

eggNOGiKOG0984. Eukaryota.
ENOG410XT3F. LUCA.

Family and domain databases

InterProiView protein in InterPro
IPR011009. Kinase-like_dom_sf.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
PfamiView protein in Pfam
PF00069. Pkinase. 1 hit.
SMARTiView protein in SMART
SM00220. S_TKc. 1 hit.
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiView protein in PROSITE
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A024R8K3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MELGRGAYGV VEKMRHVPSG QIMAVKRIRA TVNSQEQKRL LMDLDISMRT
60 70 80 90 100
VDCPFTVTFY GALFREGDVW ICMELMDTSL DKFYKQVIDK GQTIPEDILG
110 120 130 140 150
KIAVSIVKAL EHLHSKLSVI HRDVKPSNVL INALGQVKMC DFGISGYLVD
160 170 180 190 200
SVAKTIDAGC KPYMAPERIN PELNQKGYSV KSDIWSLGIT MIELAILRFP
210 220 230 240 250
YDSWGTPFQQ LKQVVEEPSP QLPADKFSAE FVDFTSQCLK KNSKERPTYP
260 270
ELMQHPFFTL HESKGTDVAS FVKLILGD
Length:278
Mass (Da):31,339
Last modified:July 9, 2014 - v1
Checksum:i1EE7FC1B26B11AE4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471099 Genomic DNA. Translation: EAW89084.1.
CH471099 Genomic DNA. Translation: EAW89086.1.
RefSeqiNP_001317379.1. NM_001330450.1.
XP_005257573.1. XM_005257516.2.
XP_006722038.1. XM_006721975.3.
XP_011523329.1. XM_011525027.2.
UniGeneiHs.463978.
Hs.49329.

Genome annotation databases

GeneIDi5608.

Similar proteinsi

Entry informationi

Entry nameiA0A024R8K3_HUMAN
AccessioniPrimary (citable) accession number: A0A024R8K3
Entry historyiIntegrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: November 22, 2017
This is version 34 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.