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Protein
Submitted name:

Serum/glucocorticoid regulated kinase family, member 3, isoform CRA_a

Gene

SGK3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.SAAS annotation

GO - Molecular functioni

Keywordsi

Molecular functionKinase, Serine/threonine-protein kinaseUniRule annotationSAAS annotation, Transferase
LigandATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Serum/glucocorticoid regulated kinase family, member 3, isoform CRA_aImported
Gene namesi
Name:SGK3Imported
ORF Names:hCG_18389Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000104205.12.
HostDB:ENSG00000270024.5.

PTM / Processingi

Proteomic databases

PaxDbiA0A024R807.
PRIDEiA0A024R807.

Expressioni

Gene expression databases

BgeeiENSG00000104205.
ExpressionAtlasiA0A024R807. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliA0A024R807.
SMRiA0A024R807.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini12 – 124PXInterPro annotationAdd BLAST113
Domaini162 – 419Protein kinaseInterPro annotationAdd BLAST258
Domaini420 – 496AGC-kinase C-terminalInterPro annotationAdd BLAST77

Sequence similaritiesi

Belongs to the protein kinase superfamily.UniRule annotation

Phylogenomic databases

eggNOGiKOG0598. Eukaryota.
KOG2101. Eukaryota.
ENOG410XNPH. LUCA.
KOiK13304.
OMAiFTEEMVP.
OrthoDBiEOG091G06FF.
PhylomeDBiA0A024R807.

Family and domain databases

Gene3Di3.30.1520.10. 1 hit.
InterProiView protein in InterPro
IPR000961. AGC-kinase_C.
IPR011009. Kinase-like_dom.
IPR001683. Phox.
IPR017892. Pkinase_C.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
PfamiView protein in Pfam
PF00069. Pkinase. 1 hit.
PF00433. Pkinase_C. 1 hit.
PF00787. PX. 1 hit.
SMARTiView protein in SMART
SM00312. PX. 1 hit.
SM00133. S_TK_X. 1 hit.
SM00220. S_TKc. 1 hit.
SUPFAMiSSF56112. SSF56112. 1 hit.
SSF64268. SSF64268. 1 hit.
PROSITEiView protein in PROSITE
PS51285. AGC_KINASE_CTER. 1 hit.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
PS50195. PX. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A024R807-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQRDHTMDYK ESCPSVSIPS SDEHREKKKR FTVYKVLVSV GRSEWFVFRR
60 70 80 90 100
YAEFDKLYNT LKKQFPAMAL KIPAKRIFGD NFDPDFIKQR RAGLNEFIQN
110 120 130 140 150
LVRYPELYNH PDVRAFLQMD SPKHQSDPSE DEDERSSQKL HSTSQNINLG
160 170 180 190 200
PSGNPHAKPT DFDFLKVIGK GSFGKVLLAK RKLDGKFYAV KVLQKKIVLN
210 220 230 240 250
RKEQKHIMAE RNVLLKNVKH PFLVGLHYSF QTTEKLYFVL DFVNGGELFF
260 270 280 290 300
HLQRERSFPE HRARFYAAEI ASALGYLHSI KIVYRDLKPE NILLDSVGHV
310 320 330 340 350
VLTDFGLCKE GIAISDTTTT FCGTPEYLAP EVIRKQPYDN TVDWWCLGAV
360 370 380 390 400
LYEMLYGLPP FYCRDVAEMY DNILHKPLSL RPGVSLTAWS ILEELLEKDR
410 420 430 440 450
QNRLGAKEDF LEIQNHPFFE SLSWADLVQK KIPPPFNPNV AGPDDIRNFD
460 470 480 490
TAFTEETVPY SVCVSSDYSI VNASVLEADD AFVGFSYAPP SEDLFL
Length:496
Mass (Da):57,108
Last modified:July 9, 2014 - v1
Checksum:i76A6CCEB69006CF1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471068 Genomic DNA. Translation: EAW86920.1.
RefSeqiNP_001028750.1. NM_001033578.2.
NP_001191102.1. NM_001204173.1.
NP_037389.4. NM_013257.4.
UniGeneiHs.613417.
Hs.733251.

Genome annotation databases

GeneIDi100533105.
23678.
KEGGihsa:100533105.
hsa:23678.

Similar proteinsi

Entry informationi

Entry nameiA0A024R807_HUMAN
AccessioniPrimary (citable) accession number: A0A024R807
Entry historyiIntegrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: September 27, 2017
This is version 29 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.