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Protein
Submitted name:

Pleiomorphic adenoma gene 1, isoform CRA_a

Gene

PLAG1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Pleiomorphic adenoma gene 1, isoform CRA_aImported
Gene namesi
Name:PLAG1Imported
ORF Names:hCG_40751Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000181690.7.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusSAAS annotation

Expressioni

Gene expression databases

BgeeiENSG00000181690.
ExpressionAtlasiA0A024R7Z0. baseline and differential.

Structurei

3D structure databases

SMRiA0A024R7Z0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini34 – 61C2H2-typeInterPro annotationAdd BLAST28
Domaini62 – 91C2H2-typeInterPro annotationAdd BLAST30
Domaini92 – 119C2H2-typeInterPro annotationAdd BLAST28
Domaini121 – 148C2H2-typeInterPro annotationAdd BLAST28
Domaini150 – 177C2H2-typeInterPro annotationAdd BLAST28
Domaini185 – 212C2H2-typeInterPro annotationAdd BLAST28
Domaini213 – 241C2H2-typeInterPro annotationAdd BLAST29

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
KOiK19484.
OMAiIDMDAVH.
OrthoDBiEOG091G061O.

Family and domain databases

Gene3Di3.30.40.10. 1 hit.
InterProiView protein in InterPro
IPR027775. C2H2_Znf_fam_sub.
IPR027765. PLAG1.
IPR013087. Znf_C2H2_type.
IPR013083. Znf_RING/FYVE/PHD.
PANTHERiPTHR10032. PTHR10032. 1 hit.
PTHR10032:SF265. PTHR10032:SF265. 1 hit.
SMARTiView protein in SMART
SM00355. ZnF_C2H2. 7 hits.
SUPFAMiSSF57667. SSF57667. 4 hits.
PROSITEiView protein in PROSITE
PS00028. ZINC_FINGER_C2H2_1. 7 hits.
PS50157. ZINC_FINGER_C2H2_2. 7 hits.

Sequencei

Sequence statusi: Complete.

A0A024R7Z0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATVIPGDLS EVRDTQKVPS GKRKRGETKP RKNFPCQLCD KAFNSVEKLK
60 70 80 90 100
VHSYSHTGER PYKCIQQDCT KAFVSKYKLQ RHMATHSPEK THKCNYCEKM
110 120 130 140 150
FHRKDHLKNH LHTHDPNKET FKCEECGKNY NTKLGFKRHL ALHAATSGDL
160 170 180 190 200
TCKVCLQTFE STGVLLEHLK SHAGKSSGGV KEKKHQCEHC DRRFYTRKDV
210 220 230 240 250
RRHMVVHTGR KDFLCQYCAQ RFGRKDHLTR HMKKSHNQEL LKVKTEPVDF
260 270 280 290 300
LDPFTCNVSV PIKDELLPVM SLPSSELLSK PFTNTLQLNL YNTPFQSMQS
310 320 330 340 350
SGSAHQMITT LPLGMTCPID MDTVHPSHHL SFKYPFSSTS YAISIPEKEQ
360 370 380 390 400
PLKGEIESYL MELQGGVPSS SQDSQASSSS KLGLDPQIGS LDDGAGDLSL
410 420 430 440 450
SKSSISISDP LNTPALDFSQ LFNFIPLNGP PYNPLSVGSL GMSYSQEEAH
460 470 480 490 500
SSVSQLPPQT QDLQDPANTI GLGSLHSLSA AFTSSLSTST TLPRFHQAFQ
Length:500
Mass (Da):55,909
Last modified:July 9, 2014 - v1
Checksum:iCF022A132A1BFD43
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471068 Genomic DNA. Translation: EAW86774.1.
CH471068 Genomic DNA. Translation: EAW86775.1.
RefSeqiNP_001108106.1. NM_001114634.1.
NP_002646.2. NM_002655.2.
XP_016869065.1. XM_017013576.1.
UniGeneiHs.14968.

Genome annotation databases

GeneIDi5324.
KEGGihsa:5324.

Similar proteinsi

Entry informationi

Entry nameiA0A024R7Z0_HUMAN
AccessioniPrimary (citable) accession number: A0A024R7Z0
Entry historyiIntegrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: September 27, 2017
This is version 30 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.