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Protein
Submitted name:

CDC37 cell division cycle 37 homolog (S. cerevisiae), isoform CRA_a

Gene

CDC37

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell divisionImported

Names & Taxonomyi

Protein namesi
Submitted name:
CDC37 cell division cycle 37 homolog (S. cerevisiae), isoform CRA_aImported
Gene namesi
Name:CDC37Imported
ORF Names:hCG_28478Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000105401.6

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PRIDEiA0A024R7B7

Expressioni

Gene expression databases

BgeeiENSG00000105401
ExpressionAtlasiA0A024R7B7 baseline and differential

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

SMRiA0A024R7B7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 127CDC37_NInterPro annotationAdd BLAST127
Domaini120 – 282CDC37_MInterPro annotationAdd BLAST163
Domaini286 – 378CDC37_CInterPro annotationAdd BLAST93

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili40 – 108Sequence analysisAdd BLAST69
Coiled coili264 – 284Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG2260 Eukaryota
ENOG410XTCZ LUCA
KOiK09554
OrthoDBiEOG091G0HL8

Family and domain databases

Gene3Di1.20.58.610, 1 hit
InterProiView protein in InterPro
IPR004918 Cdc37
IPR013873 Cdc37_C
IPR013874 Cdc37_Hsp90-bd
IPR038189 Cdc37_Hsp90-bd_sf
IPR013855 Cdc37_N_dom
PANTHERiPTHR12800 PTHR12800, 1 hit
PfamiView protein in Pfam
PF08564 CDC37_C, 1 hit
PF08565 CDC37_M, 1 hit
PF03234 CDC37_N, 1 hit
SMARTiView protein in SMART
SM01069 CDC37_C, 1 hit
SM01070 CDC37_M, 1 hit
SM01071 CDC37_N, 1 hit

Sequencei

Sequence statusi: Complete.

A0A024R7B7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVDYSVWDHI EVSDDEDETH PNIDTASLFR WRHQARVERM EQFQKEKEEL
60 70 80 90 100
DRGCRECKRK VAECQRKLKE LEVAEGGKAE LERLQAEAQQ LRKEERSWEQ
110 120 130 140 150
KLEEMRKKEK SMPWNVDTLS KDGFSKSMVN TKPEKTEEDS EEVREQKHKT
160 170 180 190 200
FVEKYEKQIK HFGMLRRWDD SQKYLSDNVH LVCEETANYL VIWCIDLEVE
210 220 230 240 250
EKCALMEQVA HQTIVMQFIL ELAKSLKVDP RACFRQFFTK IKTADRQYME
260 270 280 290 300
GFNDELEAFK ERVRGRAKLR IEKAMKEYEE EERKKRLGPG GLDPVEVYES
310 320 330 340 350
LPEELQKCFD VKDVQMLQDA ISKMDPTDAK YHMQRCIDSG LWVPNSKASE
360 370
AKEGEEAGPG DPLLEAVPKT GDEKDVSV
Length:378
Mass (Da):44,468
Last modified:July 9, 2014 - v1
Checksum:i55BFEFFF3C2A5442
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471106 Genomic DNA Translation: EAW84102.1
CH471106 Genomic DNA Translation: EAW84103.1
RefSeqiNP_008996.1, NM_007065.3
UniGeneiHs.160958

Genome annotation databases

GeneIDi11140
KEGGihsa:11140

Similar proteinsi

Entry informationi

Entry nameiA0A024R7B7_HUMAN
AccessioniPrimary (citable) accession number: A0A024R7B7
Entry historyiIntegrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: May 23, 2018
This is version 37 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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