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Protein
Submitted name:

CDC37 cell division cycle 37 homolog (S. cerevisiae), isoform CRA_a

Gene

CDC37

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell divisionImported

Names & Taxonomyi

Protein namesi
Submitted name:
CDC37 cell division cycle 37 homolog (S. cerevisiae), isoform CRA_aImported
Gene namesi
Name:CDC37Imported
ORF Names:hCG_28478Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000222005.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 127CDC37_NInterPro annotationAdd BLAST127
Domaini120 – 282CDC37_MInterPro annotationAdd BLAST163
Domaini286 – 378CDC37_CInterPro annotationAdd BLAST93

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili40 – 108Sequence analysisAdd BLAST69

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG2260. Eukaryota.
ENOG410XTCZ. LUCA.
KOiK09554.
OrthoDBiEOG091G0HL8.

Family and domain databases

InterProiView protein in InterPro
IPR004918. Cdc37.
IPR013873. Cdc37_C.
IPR013874. Cdc37_Hsp90-bd.
IPR013855. Cdc37_N_dom.
PANTHERiPTHR12800. PTHR12800. 1 hit.
PfamiView protein in Pfam
PF08564. CDC37_C. 1 hit.
PF08565. CDC37_M. 1 hit.
PF03234. CDC37_N. 1 hit.
SMARTiView protein in SMART
SM01069. CDC37_C. 1 hit.
SM01070. CDC37_M. 1 hit.
SM01071. CDC37_N. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A024R7B7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVDYSVWDHI EVSDDEDETH PNIDTASLFR WRHQARVERM EQFQKEKEEL
60 70 80 90 100
DRGCRECKRK VAECQRKLKE LEVAEGGKAE LERLQAEAQQ LRKEERSWEQ
110 120 130 140 150
KLEEMRKKEK SMPWNVDTLS KDGFSKSMVN TKPEKTEEDS EEVREQKHKT
160 170 180 190 200
FVEKYEKQIK HFGMLRRWDD SQKYLSDNVH LVCEETANYL VIWCIDLEVE
210 220 230 240 250
EKCALMEQVA HQTIVMQFIL ELAKSLKVDP RACFRQFFTK IKTADRQYME
260 270 280 290 300
GFNDELEAFK ERVRGRAKLR IEKAMKEYEE EERKKRLGPG GLDPVEVYES
310 320 330 340 350
LPEELQKCFD VKDVQMLQDA ISKMDPTDAK YHMQRCIDSG LWVPNSKASE
360 370
AKEGEEAGPG DPLLEAVPKT GDEKDVSV
Length:378
Mass (Da):44,468
Last modified:July 9, 2014 - v1
Checksum:i55BFEFFF3C2A5442
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471106 Genomic DNA. Translation: EAW84102.1.
CH471106 Genomic DNA. Translation: EAW84103.1.
RefSeqiNP_008996.1. NM_007065.3.
UniGeneiHs.160958.

Genome annotation databases

GeneIDi11140.
KEGGihsa:11140.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471106 Genomic DNA. Translation: EAW84102.1.
CH471106 Genomic DNA. Translation: EAW84103.1.
RefSeqiNP_008996.1. NM_007065.3.
UniGeneiHs.160958.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000222005.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi11140.
KEGGihsa:11140.

Organism-specific databases

CTDi11140.

Phylogenomic databases

eggNOGiKOG2260. Eukaryota.
ENOG410XTCZ. LUCA.
KOiK09554.
OrthoDBiEOG091G0HL8.

Miscellaneous databases

GenomeRNAii11140.

Family and domain databases

InterProiView protein in InterPro
IPR004918. Cdc37.
IPR013873. Cdc37_C.
IPR013874. Cdc37_Hsp90-bd.
IPR013855. Cdc37_N_dom.
PANTHERiPTHR12800. PTHR12800. 1 hit.
PfamiView protein in Pfam
PF08564. CDC37_C. 1 hit.
PF08565. CDC37_M. 1 hit.
PF03234. CDC37_N. 1 hit.
SMARTiView protein in SMART
SM01069. CDC37_C. 1 hit.
SM01070. CDC37_M. 1 hit.
SM01071. CDC37_N. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiA0A024R7B7_HUMAN
AccessioniPrimary (citable) accession number: A0A024R7B7
Entry historyiIntegrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: February 15, 2017
This is version 24 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.