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Protein
Submitted name:

Pleiotrophin (Heparin binding growth factor 8, neurite growth-promoting factor 1), isoform CRA_a

Gene

PTN

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Pleiotrophin (Heparin binding growth factor 8, neurite growth-promoting factor 1), isoform CRA_aImported
Gene namesi
Name:PTNImported
ORF Names:hCG_18946Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000105894.11

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 32Sequence analysisAdd BLAST32
ChainiPRO_500153362633 – 168Sequence analysisAdd BLAST136

Expressioni

Gene expression databases

BgeeiENSG00000105894
ExpressionAtlasiA0A024R778 baseline and differential

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliA0A024R778
SMRiA0A024R778
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini34 – 95PTN_MK_NInterPro annotationAdd BLAST62
Domaini96 – 158PTN_MK_CInterPro annotationAdd BLAST63

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IWNA Eukaryota
ENOG4111ZWP LUCA
KOiK16642
OMAiGEDICNS
OrthoDBiEOG091G0VCN
PhylomeDBiA0A024R778

Family and domain databases

Gene3Di2.20.60.10, 1 hit
2.30.90.10, 1 hit
InterProiView protein in InterPro
IPR000762 Midkine_heparin-bd_GF
IPR020090 PTN/MK_C_dom
IPR038130 PTN/MK_C_dom_sf
IPR020091 PTN/MK_diS_sf
IPR020089 PTN/MK_N_dom
IPR037122 PTN/MK_N_dom_sf
IPR020092 PTN_MK_heparin-bd_GF_CS
PANTHERiPTHR13850 PTHR13850, 1 hit
PfamiView protein in Pfam
PF01091 PTN_MK_C, 1 hit
PF05196 PTN_MK_N, 1 hit
PRINTSiPR00269 PTNMIDKINE
ProDomiView protein in ProDom or Entries sharing at least one domain
PD005592 PTN_MK_hepar_bd, 1 hit
SMARTiView protein in SMART
SM00193 PTN, 1 hit
SUPFAMiSSF57288 SSF57288, 2 hits
PROSITEiView protein in PROSITE
PS00619 PTN_MK_1, 1 hit
PS00620 PTN_MK_2, 1 hit

Sequencei

Sequence statusi: Complete.

A0A024R778-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQAQQYQQQR RKFAAAFLAF IFILAAVDTA EAGKKEKPEK KVKKSDCGEW
60 70 80 90 100
QWSVCVPTSG DCGLGTREGT RTGAECKQTM KTQRCKIPCN WKKQFGAECK
110 120 130 140 150
YQFQAWGECD LNTALKTRTG SLKRALHNAE CQKTVTISKP CGKLTKPKPQ
160
AESKKKKKEG KKQEKMLD
Length:168
Mass (Da):18,942
Last modified:July 9, 2014 - v1
Checksum:i0359C08B6497B579
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471070 Genomic DNA Translation: EAW83872.1
RefSeqiNP_001308315.1, NM_001321386.2
NP_002816.1, NM_002825.6
UniGeneiHs.371249

Genome annotation databases

GeneIDi5764
KEGGihsa:5764

Similar proteinsi

Entry informationi

Entry nameiA0A024R778_HUMAN
AccessioniPrimary (citable) accession number: A0A024R778
Entry historyiIntegrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: May 23, 2018
This is version 30 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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