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Protein
Submitted name:

HMG-box transcription factor 1, isoform CRA_a

Gene

HBP1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi434 – 502HMG boxPROSITE-ProRule annotationAdd BLAST69

GO - Molecular functioni

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
HMG-box transcription factor 1, isoform CRA_aImported
Gene namesi
Name:HBP1Imported
ORF Names:hCG_17934Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotation

PTM / Processingi

Proteomic databases

PaxDbiA0A024R722.
PRIDEiA0A024R722.

Expressioni

Gene expression databases

ExpressionAtlasiA0A024R722. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000222574.

Structurei

3D structure databases

ProteinModelPortaliA0A024R722.
SMRiA0A024R722.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini203 – 345AXHInterPro annotationAdd BLAST143
Domaini434 – 502HMG box DNA-bindingInterPro annotationAdd BLAST69

Phylogenomic databases

eggNOGiENOG410IFNF. Eukaryota.
ENOG410XPPV. LUCA.
OMAiPSTAWHC.
OrthoDBiEOG091G0SF1.
PhylomeDBiA0A024R722.

Family and domain databases

Gene3Di1.10.30.10. 1 hit.
InterProiView protein in InterPro
IPR003652. Ataxin_AXH_dom.
IPR009071. HMG_box_dom.
PfamiView protein in Pfam
PF08517. AXH. 1 hit.
PF00505. HMG_box. 1 hit.
SMARTiView protein in SMART
SM00536. AXH. 1 hit.
SM00398. HMG. 1 hit.
SUPFAMiSSF102031. SSF102031. 1 hit.
SSF47095. SSF47095. 1 hit.
PROSITEiView protein in PROSITE
PS51148. AXH. 1 hit.
PS50118. HMG_BOX_2. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A024R722-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVWEVKTNQM PNAVQKLLLV MDKRASGMND SLELLQCNEN LPSSPGYNSC
60 70 80 90 100
DEHMELDDLP ELQAVQSDPT QSGMYQLSSD VSHQEYPRSS WNQNTSDIPE
110 120 130 140 150
TTYRENEVDW LTELANIATS PQSPLMQCSF YNRSSPVHII ATSKSLHSYA
160 170 180 190 200
RPPPVSSSSK SEPAFPHHHW KEETPVRHER ANSESESGIF CMSSLSDDDD
210 220 230 240 250
LGWCNSWPST VWHCFLKGTR LCFHKGSNKE WQDVEDFARA EGCDNEEDLQ
260 270 280 290 300
MGIHKGYGSD GLKLLSHEES VSFGESVLKL TFDPGTVEDG LLTVECKLDH
310 320 330 340 350
PFYVKNKGWS SFYPSLTVVQ HGIPCCEVHI GDVCLPPGHP DAINFDDSGV
360 370 380 390 400
FDTFKSYDFT PMDSSAVYVL SSMARQRRAS LSCGGPGGQD FARSGFSKNC
410 420 430 440 450
GSPGSSQLSS NSLYAKAVKN HSSGTVSATS PNKCKRPMNA FMLFAKKYRV
460 470 480 490 500
EYTQMYPGKD NRAISVILGD RWKKMKNEER RMYTLEAKAL AEEQKRLNPD
510
CWKRKRTNSG SQQH
Length:514
Mass (Da):57,645
Last modified:July 9, 2014 - v1
Checksum:i2AFADC995F73A031
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471070 Genomic DNA. Translation: EAW83394.1.
RefSeqiNP_036389.2. NM_012257.3.
XP_005250323.1. XM_005250266.2.
XP_005250324.1. XM_005250267.2.
XP_016867456.1. XM_017011967.1.
UniGeneiHs.162032.

Genome annotation databases

GeneIDi26959.
KEGGihsa:26959.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471070 Genomic DNA. Translation: EAW83394.1.
RefSeqiNP_036389.2. NM_012257.3.
XP_005250323.1. XM_005250266.2.
XP_005250324.1. XM_005250267.2.
XP_016867456.1. XM_017011967.1.
UniGeneiHs.162032.

3D structure databases

ProteinModelPortaliA0A024R722.
SMRiA0A024R722.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000222574.

Proteomic databases

PaxDbiA0A024R722.
PRIDEiA0A024R722.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi26959.
KEGGihsa:26959.

Organism-specific databases

CTDi26959.

Phylogenomic databases

eggNOGiENOG410IFNF. Eukaryota.
ENOG410XPPV. LUCA.
OMAiPSTAWHC.
OrthoDBiEOG091G0SF1.
PhylomeDBiA0A024R722.

Miscellaneous databases

GenomeRNAii26959.

Gene expression databases

ExpressionAtlasiA0A024R722. baseline and differential.

Family and domain databases

Gene3Di1.10.30.10. 1 hit.
InterProiView protein in InterPro
IPR003652. Ataxin_AXH_dom.
IPR009071. HMG_box_dom.
PfamiView protein in Pfam
PF08517. AXH. 1 hit.
PF00505. HMG_box. 1 hit.
SMARTiView protein in SMART
SM00536. AXH. 1 hit.
SM00398. HMG. 1 hit.
SUPFAMiSSF102031. SSF102031. 1 hit.
SSF47095. SSF47095. 1 hit.
PROSITEiView protein in PROSITE
PS51148. AXH. 1 hit.
PS50118. HMG_BOX_2. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiA0A024R722_HUMAN
AccessioniPrimary (citable) accession number: A0A024R722
Entry historyiIntegrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: February 15, 2017
This is version 19 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.