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Protein
Submitted name:

Chromosome 14 open reading frame 172, isoform CRA_b

Gene

C14orf172

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei135 – 1351S-adenosyl-L-methionineUniRule annotation
Binding sitei163 – 1631S-adenosyl-L-methionineUniRule annotation
Binding sitei181 – 1811S-adenosyl-L-methionineUniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

S-adenosyl-L-methionineUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Chromosome 14 open reading frame 172, isoform CRA_bImported
Gene namesi
Name:C14orf172Imported
ORF Names:hCG_25505Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000374399.

Family & Domainsi

Phylogenomic databases

eggNOGiKOG2915. Eukaryota.
COG2519. LUCA.
KOiK07442.
OMAiTTQMSRL.
OrthoDBiEOG091G0BHV.
PhylomeDBiA0A024R6Q2.

Family and domain databases

Gene3Di3.40.50.150. 2 hits.
InterProiIPR029063. SAM-dependent_MTases.
IPR014816. tRNA_MeTrfase_Gcd14.
[Graphical view]
PfamiPF08704. GCD14. 1 hit.
[Graphical view]
PIRSFiPIRSF017269. GCD14. 1 hit.
SUPFAMiSSF53335. SSF53335. 1 hit.
PROSITEiPS51620. SAM_TRM61. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A0A024R6Q2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSFVAYEELI KEGDTAILSL GHGAMVAVRV QRGAQTQTRH GVLRHSVDLI
60 70 80 90 100
GRPFGSKVTC GRGGWVYVLH PTPELWTLNL PHRTQILYST DIALITMMLE
110 120 130 140 150
LRPGSVVCES GTGSGSVSHA IIRTIAPTGH LHTVEFHQQR AEKAREEFQE
160 170 180 190 200
HRVGRWVTVR TQDVCRSGFG VSHVADAVFL DIPSPWEAVG HAWDALKVEG
210 220 230 240 250
GRFCSFSPCI EQVQRTCQAL AARGFSELST LEVLPQVYNV RTVSLPPPDL
260 270 280
GTGTDGPAGS DTSPFRSGTP MKEAVGHTGY LTFATKTPG
Length:289
Mass (Da):31,382
Last modified:July 9, 2014 - v1
Checksum:i5DCD6437A0B6F54D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471061 Genomic DNA. Translation: EAW81824.1.
CH471061 Genomic DNA. Translation: EAW81825.1.
RefSeqiNP_689520.2. NM_152307.2.
UniGeneiHs.525610.

Genome annotation databases

GeneIDi115708.
KEGGihsa:115708.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471061 Genomic DNA. Translation: EAW81824.1.
CH471061 Genomic DNA. Translation: EAW81825.1.
RefSeqiNP_689520.2. NM_152307.2.
UniGeneiHs.525610.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000374399.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi115708.
KEGGihsa:115708.

Organism-specific databases

CTDi115708.

Phylogenomic databases

eggNOGiKOG2915. Eukaryota.
COG2519. LUCA.
KOiK07442.
OMAiTTQMSRL.
OrthoDBiEOG091G0BHV.
PhylomeDBiA0A024R6Q2.

Miscellaneous databases

GenomeRNAii115708.

Family and domain databases

Gene3Di3.40.50.150. 2 hits.
InterProiIPR029063. SAM-dependent_MTases.
IPR014816. tRNA_MeTrfase_Gcd14.
[Graphical view]
PfamiPF08704. GCD14. 1 hit.
[Graphical view]
PIRSFiPIRSF017269. GCD14. 1 hit.
SUPFAMiSSF53335. SSF53335. 1 hit.
PROSITEiPS51620. SAM_TRM61. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiA0A024R6Q2_HUMAN
AccessioniPrimary (citable) accession number: A0A024R6Q2
Entry historyi
Integrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: September 7, 2016
This is version 19 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.