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Protein
Submitted name:

BCL2-interacting killer (Apoptosis-inducing), isoform CRA_a

Gene

BIK

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
BCL2-interacting killer (Apoptosis-inducing), isoform CRA_aImported
Gene namesi
Name:BIKImported
ORF Names:hCG_1734392Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000100290.2.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei136 – 159HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiA0A024R4X6.
PRIDEiA0A024R4X6.

Expressioni

Gene expression databases

BgeeiENSG00000100290.
ExpressionAtlasiA0A024R4X6. baseline and differential.

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliA0A024R4X6.
SMRiA0A024R4X6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410JHX0. Eukaryota.
ENOG41116I0. LUCA.
KOiK18452.
OMAiIYDQTED.
OrthoDBiEOG091G0VGV.
PhylomeDBiA0A024R4X6.

Family and domain databases

InterProiView protein in InterPro
IPR024579. Bcl2-int_killer.
IPR020728. Bcl2_BH3_motif_CS.
PANTHERiPTHR15018. PTHR15018. 1 hit.
PfamiView protein in Pfam
PF12201. bcl-2I13. 1 hit.
ProDomiView protein in ProDom or Entries sharing at least one domain
PD032623. PD032623. 1 hit.
PROSITEiView protein in PROSITE
PS01259. BH3. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A024R4X6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEVRPLSRD ILMETLLYEQ LLEPPTMEVL GMTDSEEDLD PMEDFDSLEC
60 70 80 90 100
MEGSDALALR LACIGDEMDV SLRAPRLAQL SEVAMHSLGL AFIYDQTEDI
110 120 130 140 150
RDVLRSFMDG FTTLKENIMR FWRSPNPGSW VSCEQVLLAL LLLLALLLPL
160
LSGGLHLLLK
Length:160
Mass (Da):18,016
Last modified:July 9, 2014 - v1
Checksum:i89034F4443F5A136
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471138 Genomic DNA. Translation: EAW73284.1.
RefSeqiNP_001188.1. NM_001197.4.
UniGeneiHs.475055.

Genome annotation databases

GeneIDi638.
KEGGihsa:638.

Similar proteinsi

Entry informationi

Entry nameiA0A024R4X6_HUMAN
AccessioniPrimary (citable) accession number: A0A024R4X6
Entry historyiIntegrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: September 27, 2017
This is version 21 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.