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Protein
Submitted name:

TAR DNA binding protein, isoform CRA_b

Gene

TARDBP

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRNA-bindingPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
TAR DNA binding protein, isoform CRA_bImported
Gene namesi
Name:TARDBPImported
ORF Names:hCG_2005583Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000120948.15

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PRIDEiA0A024R4E2

Expressioni

Gene expression databases

BgeeiENSG00000120948
ExpressionAtlasiA0A024R4E2 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliA0A024R4E2
SMRiA0A024R4E2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini104 – 200RRMInterPro annotationAdd BLAST97
Domaini191 – 262RRMInterPro annotationAdd BLAST72

Phylogenomic databases

eggNOGiENOG410IFJS Eukaryota
ENOG410ZYQJ LUCA
OMAiFCEIKRK
OrthoDBiEOG091G0BJZ
PhylomeDBiA0A024R4E2

Family and domain databases

Gene3Di3.30.70.330, 2 hits
InterProiView protein in InterPro
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR035979 RBD_domain_sf
IPR000504 RRM_dom
PfamiView protein in Pfam
PF00076 RRM_1, 2 hits
SMARTiView protein in SMART
SM00360 RRM, 2 hits
SUPFAMiSSF54928 SSF54928, 2 hits
PROSITEiView protein in PROSITE
PS50102 RRM, 2 hits

Sequencei

Sequence statusi: Complete.

A0A024R4E2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEYIRVTED ENDEPIEIPS EDDGTVLLST VTAQFPGACG LRYRNPVSQC
60 70 80 90 100
MRGVRLVEGI LHAPDAGWGN LVYVVNYPKD NKRKMDETDA SSAVKVKRAV
110 120 130 140 150
QKTSDLIVLG LPWKTTEQDL KEYFSTFGEV LMVQVKKDLK TGHSKGFGFV
160 170 180 190 200
RFTEYETQVK VMSQRHMIDG RWCDCKLPNS KQSQDEPLRS RKVFVGRCTE
210 220 230 240 250
DMTEDELREF FSQYGDVMDV FIPKPFRAFA FVTFADDQIA QSLCGEDLII
260 270 280 290 300
KGISVHISNA EPKHNSNRQL ERSGRFGGNP GGFGNQGGFG NSRGGGAGLG
310 320 330 340 350
NNQGSNMGGG MNFGAFSINP AMMAAAQAAL QSSWGMMGML ASQQNQSGPS
360 370 380 390 400
GNNQNQGNMQ REPNQAFGSG NNSYSGSNSG AAIGWGSASN AGSGSGFNGG
410
FGSSMDSKSS GWGM
Length:414
Mass (Da):44,740
Last modified:July 9, 2014 - v1
Checksum:i8E09A1206FB4EF4A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471130 Genomic DNA Translation: EAW71671.1
RefSeqiNP_031401.1, NM_007375.3
XP_016856352.1, XM_017000863.1
XP_016856353.1, XM_017000864.1
XP_016856354.1, XM_017000865.1
XP_016856355.1, XM_017000866.1
XP_016856356.1, XM_017000867.1
XP_016856357.1, XM_017000868.1
UniGeneiHs.300624

Genome annotation databases

GeneIDi23435
KEGGihsa:23435

Similar proteinsi

Entry informationi

Entry nameiA0A024R4E2_HUMAN
AccessioniPrimary (citable) accession number: A0A024R4E2
Entry historyiIntegrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: April 25, 2018
This is version 30 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health