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Protein
Submitted name:

Lectin, mannose-binding, 1, isoform CRA_b

Gene

LMAN1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Lectin, mannose-binding, 1, isoform CRA_bImported
Gene namesi
Name:LMAN1Imported
ORF Names:hCG_1979190Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei479 – 498HelicalSequence analysisAdd BLAST20

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 30Sequence analysisAdd BLAST30
ChainiPRO_500845345331 – 510Sequence analysisAdd BLAST480

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000251047.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini44 – 267L-type lectin-likeInterPro annotationAdd BLAST224

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili279 – 306Sequence analysisAdd BLAST28

Keywords - Domaini

Coiled coilSequence analysis, SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3838. Eukaryota.
ENOG410ZFRX. LUCA.
KOiK10080.
OMAiNMIIPAQ.
OrthoDBiEOG091G08WZ.

Family and domain databases

Gene3Di2.60.120.200. 1 hit.
InterProiIPR013320. ConA-like_dom.
IPR005052. Lectin_leg.
IPR033085. LMAN1.
[Graphical view]
PANTHERiPTHR12223:SF32. PTHR12223:SF32. 1 hit.
PfamiPF03388. Lectin_leg-like. 1 hit.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 1 hit.
PROSITEiPS51328. L_LECTIN_LIKE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A0A024R2A7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGSRQRGLR ARVRPLFCAL LLSLGRFVRG DGVGGDPAVA LPHRRFEYKY
60 70 80 90 100
SFKGPHLVQS DGTVPFWAHA GNAIPSSDQI RVAPSLKSQR GSVWTKTKAA
110 120 130 140 150
FENWEVEVTF RVTGRGRIGA DGLAIWYAEN QGLEGPVFGS ADLWNGVGIF
160 170 180 190 200
FDSFDNDGKK NNPAIVIIGN NGQIHYDHQN DGASQALASC QRDFRNKPYP
210 220 230 240 250
VRAKITYYQN TLTVMINNGF TPDKNDYEFC AKVENMIIPA QGHFGISAAT
260 270 280 290 300
GGLADDHDVL SFLTFQLTEP GKEPPTPDKE ISEKEKEKYQ EEFEHFQQEL
310 320 330 340 350
DKKKEEFQKG HPDLQGQPAE EIFESVGDRE LRQVFEGQNR IHLEIKQLNR
360 370 380 390 400
QLDMILDEQR RYVSSLTEEI SKRGAGMPGQ HGQITQQELD TVVKTQHEIL
410 420 430 440 450
RQVNEMKNSM SETVRLVSGM QHPGSAGGVY ETTQHFIDIK EHLHIVKRDI
460 470 480 490 500
DNLVQRNMPS NEKPKCPELP PFPSCLSTVH FIIFVVVQTV LFIGYIMYRS
510
QQEAAAKKFF
Length:510
Mass (Da):57,549
Last modified:July 9, 2014 - v1
Checksum:iB87EF117C0CD386C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471096 Genomic DNA. Translation: EAW63097.1.
CH471096 Genomic DNA. Translation: EAW63098.1.
RefSeqiNP_005561.1. NM_005570.3.
UniGeneiHs.465295.

Genome annotation databases

GeneIDi3998.
KEGGihsa:3998.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471096 Genomic DNA. Translation: EAW63097.1.
CH471096 Genomic DNA. Translation: EAW63098.1.
RefSeqiNP_005561.1. NM_005570.3.
UniGeneiHs.465295.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000251047.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi3998.
KEGGihsa:3998.

Organism-specific databases

CTDi3998.

Phylogenomic databases

eggNOGiKOG3838. Eukaryota.
ENOG410ZFRX. LUCA.
KOiK10080.
OMAiNMIIPAQ.
OrthoDBiEOG091G08WZ.

Miscellaneous databases

GenomeRNAii3998.

Family and domain databases

Gene3Di2.60.120.200. 1 hit.
InterProiIPR013320. ConA-like_dom.
IPR005052. Lectin_leg.
IPR033085. LMAN1.
[Graphical view]
PANTHERiPTHR12223:SF32. PTHR12223:SF32. 1 hit.
PfamiPF03388. Lectin_leg-like. 1 hit.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 1 hit.
PROSITEiPS51328. L_LECTIN_LIKE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiA0A024R2A7_HUMAN
AccessioniPrimary (citable) accession number: A0A024R2A7
Entry historyi
Integrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: November 30, 2016
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.