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Protein
Submitted name:

Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide, isoform CRA_b

Gene

YWHAH

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMonooxygenaseImported, Oxidoreductase

Names & Taxonomyi

Protein namesi
Submitted name:
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide, isoform CRA_bImported
Gene namesi
Name:YWHAHImported
ORF Names:hCG_41511Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Expressioni

Gene expression databases

BgeeiENSG00000128245.
ExpressionAtlasiA0A024R1K7. baseline and differential.

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

SMRiA0A024R1K7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 24614_3_3InterPro annotationAdd BLAST243

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili72 – 95Sequence analysisAdd BLAST24

Sequence similaritiesi

Belongs to the 14-3-3 family.UniRule annotationSAAS annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0841. Eukaryota.
COG5040. LUCA.
KOiK16198.
OMAiCERYEDM.
OrthoDBiEOG091G0VKY.

Family and domain databases

Gene3Di1.20.190.20. 1 hit.
InterProiView protein in InterPro
IPR000308. 14-3-3.
IPR023409. 14-3-3_CS.
IPR023410. 14-3-3_domain.
PANTHERiPTHR18860. PTHR18860. 1 hit.
PfamiView protein in Pfam
PF00244. 14-3-3. 1 hit.
PIRSFiPIRSF000868. 14-3-3. 1 hit.
PRINTSiPR00305. 1433ZETA.
SMARTiView protein in SMART
SM00101. 14_3_3. 1 hit.
SUPFAMiSSF48445. SSF48445. 1 hit.
PROSITEiView protein in PROSITE
PS00796. 1433_1. 1 hit.
PS00797. 1433_2. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A024R1K7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGDREQLLQR ARLAEQAERY DDMASAMKAV TELNEPLSNE DRNLLSVAYK
60 70 80 90 100
NVVGARRSSW RVISSIEQKT MADGNEKKLE KVKAYREKIE KELETVCNDV
110 120 130 140 150
LSLLDKFLIK NCNDFQYESK VFYLKMKGDY YRYLAEVASG EKKNSVVEAS
160 170 180 190 200
EAAYKEAFEI SKEQMQPTHP IRLGLALNFS VFYYEIQNAP EQACLLAKQA
210 220 230 240
FDDAIAELDT LNEDSYKDST LIMQLLRDNL TLWTSDQQDE EAGEGN
Length:246
Mass (Da):28,219
Last modified:July 9, 2014 - v1
Checksum:iD70FBC100C45D6E5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471095 Genomic DNA. Translation: EAW60002.1.
CH471095 Genomic DNA. Translation: EAW60003.1.
RefSeqiNP_003396.1. NM_003405.3.
UniGeneiHs.226755.

Genome annotation databases

GeneIDi7533.
KEGGihsa:7533.

Similar proteinsi

Entry informationi

Entry nameiA0A024R1K7_HUMAN
AccessioniPrimary (citable) accession number: A0A024R1K7
Entry historyiIntegrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: August 30, 2017
This is version 30 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.